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LC-MS/MS Quantitative Analysis of Quorum Sensing Signal Molecules (2014)
Book Chapter
Ortori, C. A., Ortori, C., Halliday, N., Cámara, M., Williams, P., & Barrett, D. A. (2014). LC-MS/MS Quantitative Analysis of Quorum Sensing Signal Molecules. In A. Filloux, & J. Ramos (Eds.), Pseudomonas Methods and Protocols (255-270). Springer. https://doi.org/10.1007/978-1-4939-0473-0_21

© Springer Science+Business Media New York 2014. Extracts taken from spent growth media from Pseudomonas aeruginosa can be analyzed for N -acyl- L - homoserine lactones and 2-alkyl-4-(1 H)-quinolones (AQs), including the known quorum sensing signalli... Read More about LC-MS/MS Quantitative Analysis of Quorum Sensing Signal Molecules.

Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors (2014)
Journal Article
Murray, E. J., Crowley, R. C., Truman, A., Clarke, S. R., Cottam, J. A., Jadhav, G. P., …Williams, P. (2014). Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors. Journal of Medicinal Chemistry, 57(6), 2813-2819. https://doi.org/10.1021/jm500215s

A series of 3-oxo-C 12 -HSL, tetramic acid, and tetronic acid analogues were synthesized to gain insights into the structural requirements for quorum sensing inhibition in Staphylococcus aureus. Compounds active against agr were noncompetitive inhibi... Read More about Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors.