Engaging and developing the frontline clinical nurse to drive care excellence: evaluating the Chief Nurse Junior Excellence in Care Fellowship Initiative (2018)
Journal Article
Bramley, L., Manning, J., & Cooper, J. (2018). Engaging and developing the frontline clinical nurse to drive care excellence: evaluating the Chief Nurse Junior Excellence in Care Fellowship Initiative. International Journal of Research in Nursing, 16(12), 1977-1990. https://doi.org/10.1177/1744987118808843

Background

Global challenges in the development of a highly skilled and motivated nursing workforce, jeopardises the delivery of high quality care. Flexible and innovative workforce solutions are required to overcome these challenges.

Aims... Read More about Engaging and developing the frontline clinical nurse to drive care excellence: evaluating the Chief Nurse Junior Excellence in Care Fellowship Initiative.

Parents’ and carers’ experiences of transition and aftercare following a child’s discharge from a paediatric intensive care unit to an in-patient ward setting: A qualitative systematic review (2018)
Journal Article
Suleman, Z., Evans, C., & Manning, J. (2019). Parents’ and carers’ experiences of transition and aftercare following a child’s discharge from a paediatric intensive care unit to an in-patient ward setting: A qualitative systematic review. Intensive and Critical Care Nursing, 51, 35-44. https://doi.org/10.1016/j.iccn.2018.10.003

Objectives: To explore parents’ experiences of transition and aftercare following their child’s discharge from a pediatric intensive care unit to an inpatient ward.
Methods: A qualitative systematic review was conducted. Electronic databases CINAHL,... Read More about Parents’ and carers’ experiences of transition and aftercare following a child’s discharge from a paediatric intensive care unit to an in-patient ward setting: A qualitative systematic review.

Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists (2018)
Journal Article
Adlere, I., Sun, S., Zarca, A., Roumen, L., Gozelle, M., Viciano, C. P., …Leurs, R. (2019). Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists. European Journal of Medicinal Chemistry, 162, 631-649. https://doi.org/10.1016/j.ejmech.2018.10.060

Using the available structural information of the chemokine receptor CXCR4, we present hit finding and hit exploration studies that make use of virtual fragment screening, design, synthesis and structure-activity relationship (SAR) studies. Fragment... Read More about Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists.

Cortical correlates of speech intelligibility measured using functional near-infrared spectroscopy (fNIRS) (2018)
Journal Article
Lawrence, R. J., Wiggins, I. M., Anderson, C. A., Davies-Thompson, J., & Hartley, D. E. (2018). Cortical correlates of speech intelligibility measured using functional near-infrared spectroscopy (fNIRS). Hearing Research, 370, 53-64. https://doi.org/10.1016/j.heares.2018.09.005

Functional neuroimaging has identified that the temporal, frontal and parietal cortex support core aspects of speech processing. An objective measure of speech intelligibility based on cortical activation in these brain regions would be extremely use... Read More about Cortical correlates of speech intelligibility measured using functional near-infrared spectroscopy (fNIRS).

Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis (2018)
Journal Article
Mbanefo, E. C., Le, L., Pennington, L. F., Odegaard, J. I., Jardetzky, T. S., Alouffi, A., …Hsieh, M. H. (2018). Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis. FASEB Journal, 32(8), 4408-4419. https://doi.org/10.1096/fj.201701415r

Chemotherapy-induced hemorrhagic cystitis (CHC) can be difficult to manage. Prior work suggests that IL-4 alleviates ifosfamide-induced hemorrhagic cystitis (IHC), but systemically administered IL-4 causes significant side effects. We hypothesized th... Read More about Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis.