Skip to main content

Research Repository

Advanced Search

Dr STEFAN KLUZEK's Outputs (34)

Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review (2018)
Journal Article
Cairns, G., Owen, T., Kluzek, S., Thurley, N., Holden, S., Rathleff, M. S., & Dean, B. J. F. (2018). Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review. BMJ Open Sport and Exercise Medicine, 4(1), Article e000383. https://doi.org/10.1136/bmjsem-2018-000383

Objective: Evaluate effectiveness and harms of interventions for patellar tendon related pain in children and adolescents.

Design: Systematic review and meta-analysis.

Data sources: Medline via Pubmed, Embase via OVID, CINAHL via Ebsco, SportDi... Read More about Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review.

Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women (2018)
Journal Article
Sanchez-Santos, M., Judge, A., Gulati, M., Spector, T., Hart, D., Newton, J., Arden, N., & Kluzek, S. (2019). Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women. Seminars in Arthritis and Rheumatism, 48(5), 791-798. https://doi.org/10.1016/j.semarthrit.2018.07.007

Objective

It is unclear whether the association between osteoarthritis (OA) and metabolic syndrome (MetS) varies with the site of the affected joint and the presence of pain. Our aim was to describe the association between MetS and radiographic OA... Read More about Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women.

Partial mid-portion Achilles tear resulting in substantial improvement in pain and function in an amateur long-distance runner (2018)
Journal Article
Woyton, M. M., Kluzek, S., Wedatilake, T., & Davies, M. A. M. (2018). Partial mid-portion Achilles tear resulting in substantial improvement in pain and function in an amateur long-distance runner. BMJ Case Reports, 2018, Article bcr-2018-225823. https://doi.org/10.1136/bcr-2018-225823

This case presents symptom resolution for a long-distance runner with chronic Achilles tendinopathy (AT), following a partial tear of his Achilles tendon. The patient reported a sudden pain during a morning run, with preserved function. Three hours p... Read More about Partial mid-portion Achilles tear resulting in substantial improvement in pain and function in an amateur long-distance runner.

Confusion and abdominal symptoms following a rugby tackle (2017)
Journal Article
Ioannides, D., Davies, M., & Kluzek, S. (2017). Confusion and abdominal symptoms following a rugby tackle. BMJ Case Reports, 2017, Article bcr-2017-222160. https://doi.org/10.1136/bcr-2017-222160

A 19-year-old man was sent to the emergency department following a pitch-side assessment for suspected concussion, unexplained upper abdominal tenderness and vomiting, following a high-impact tackle during a rugby match. A Focussed Assessment with So... Read More about Confusion and abdominal symptoms following a rugby tackle.

A large chronic pericardial effusion in an ultramarathon runner with anti-CCP positive rheumatoid arthritis (2017)
Journal Article
McClelland, T. J., Penfold, R., Kluzek, S., & Nagra, N. S. (2017). A large chronic pericardial effusion in an ultramarathon runner with anti-CCP positive rheumatoid arthritis. BMJ Case Reports, 2017, Article bcr-2017-219350. https://doi.org/10.1136/bcr-2017-219350

Pericardial effusions arise as an extra-articular manifestation of rheumatoid arthritis (RA). Pericardial effusions are often asymptomatic, particularly in the early phase, but patients are at risk of cardiac tamponade as the effusion progresses. We... Read More about A large chronic pericardial effusion in an ultramarathon runner with anti-CCP positive rheumatoid arthritis.

Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy (2016)
Journal Article
Wallace, G., Cro, S., Doré, C., King, L., Kluzek, S., Price, A., Roemer, F., Guermazi, A., Keen, R., & Arden, N. (2017). Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy. Arthritis Care and Research, 69(9), 1340-1348. https://doi.org/10.1002/acr.23162

Objective

Painful knee osteoarthritis (KOA) has been associated with joint inflammation. There is, however, little literature correlating signs of localized inflammation with contrast‐enhanced (CE) magnetic resonance imaging (MRI) of synovium. Thi... Read More about Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy.

Response to: ‘Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women’ by Gao et al (2016)
Journal Article
Kluzek, S., Sanchez-Santos, M. T., Leyland, K. M., Judge, A., Newton, J., & Arden, N. K. (2016). Response to: ‘Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women’ by Gao et al. Annals of the Rheumatic Diseases, 75(4), Article e23. https://doi.org/10.1136/annrheumdis-2015-209029

Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women (2015)
Journal Article
Kluzek, S., Bay-Jensen, A.-C., Judge, A., Karsdal, M. A., Shorthose, M., Spector, T., Hart, D., Newton, J. L., & Arden, N. K. (2015). Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women. Biomarkers, 20(8), 557-564. https://doi.org/10.3109/1354750x.2015.1105498

Context and objective: We evaluated the predictive value of serum cartilage oligomeric matrix protein (sCOMP) levels over 20 years on the development of radiographic (RKOA) and painful knee osteoarthritis (KOA) in a longitudinal cohort of middle-aged... Read More about Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women.

Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women (2015)
Journal Article
Kluzek, S., Sanchez-Santos, M. T., Leyland, K. M., Judge, A., Spector, T. D., Hart, D., Cooper, C., Newton, J., & Arden, N. K. (2016). Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women. Annals of the Rheumatic Diseases, 75(10), 1749-1756. https://doi.org/10.1136/annrheumdis-2015-208056

To assess whether joint pain or radiographic osteoarthritis (ROA) of the knee and hand is associated with all-cause and disease-specific mortality in middle-aged women.

Methods: Four subgroups from the prospective community-based Chingford Cohort... Read More about Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women.

Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis (2015)
Journal Article
Williamson, W., Kluzek, S., Roberts, N., Richards, J., Arden, N., Leeson, P., Newton, J., & Foster, C. (2015). Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis. BMJ Open, 5(8), Article e007642. https://doi.org/10.1136/bmjopen-2015-007642

Objective: To assess effectiveness of osteoarthritis interventions to promote long-term physical activity behaviour change.

Design: A systematic review and meta-analysis. Protocol registration PROSPERO CRD4201300444 5 (http://www.crd.york.ac.uk/pr... Read More about Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis.

Is osteoarthritis a metabolic disorder? (2015)
Journal Article
Kluzek, S., Newton, J. L., & Arden, N. K. (2015). Is osteoarthritis a metabolic disorder?. British Medical Bulletin, 115(1), 111-121. https://doi.org/10.1093/bmb/ldv028

Background

Obesity is associated with an increased risk of developing osteoarthritis (OA), even in non-weight bearing joints. High levels of adipose tissue-associated inflammation may explain this association.

Sources of data and areas of debat... Read More about Is osteoarthritis a metabolic disorder?.

Adipokines as potential prognostic biomarkers in patients with acute knee injury (2015)
Journal Article
Kluzek, S., Arden, N. K., & Newton, J. (2015). Adipokines as potential prognostic biomarkers in patients with acute knee injury. Biomarkers, 20(8), 519-525. https://doi.org/10.3109/1354750x.2014.948914

This review considers adipokines as predictive biomarkers for early onset post-traumatic knee osteoarthritis (KOA). Serum concentrations of leptin and resistin can predict radiographic changes and are elevated in early KOA, with higher leptin concent... Read More about Adipokines as potential prognostic biomarkers in patients with acute knee injury.

Acute compartment syndrome of the thigh in a rugby player (2015)
Journal Article
Smith, R. D. J., Rust-March, H., & Kluzek, S. (2015). Acute compartment syndrome of the thigh in a rugby player. BMJ Case Reports, 2015, Article bcr2015210856. https://doi.org/10.1136/bcr-2015-210856

In the absence of obvious trauma, diagnosis of acute compartment syndrome (ACS) of the thigh can easily be delayed, as disproportional pain is not always present. We present a case of ACS of the anterior right thigh compartment in a healthy, semiprof... Read More about Acute compartment syndrome of the thigh in a rugby player.