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STEFAN KLUZEK's Outputs (43)

Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – Findings from the ADVANCE study (2024)
Journal Article
O'Sullivan, O., Stocks, J., Schofield, S., Bilzon, J., Boos, C. J., Bull, A. M., Fear, N. T., Watt, F. E., Bennett, A. N., Kluzek, S., & Valdes, A. M. (2024). Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – Findings from the ADVANCE study. Osteoarthritis and Cartilage, 32(12), 1636-1646. https://doi.org/10.1016/j.joca.2024.07.016

Objective: The ArmeD SerVices TrAuma RehabilitatioN OutComE (ADVANCE) study is investigating long-term combat-injury outcomes; this sub-study aims to understand the association of osteoarthritis (OA) biomarkers with knee radiographic OA (rOA), pain a... Read More about Association of serum biomarkers with radiographic knee osteoarthritis, knee pain and function in a young, male, trauma-exposed population – Findings from the ADVANCE study.

Comparing Self-Reported Running Distance and Pace With a Commercial Fitness Watch Data: Reliability Study (2024)
Journal Article
Bullock, G., Stocks, J., Feakins, B., Alizadeh, Z., Arundale, A., & Kluzek, S. (2024). Comparing Self-Reported Running Distance and Pace With a Commercial Fitness Watch Data: Reliability Study. JMIR Formative Research, 8(1), Article e39211. https://doi.org/10.2196/39211

Background There is substantial evidence exploring the reliability of running distance self-reporting and GPS wearable technology, but there are currently no studies investigating the reliability of participant self-reporting in comparison to GPS wea... Read More about Comparing Self-Reported Running Distance and Pace With a Commercial Fitness Watch Data: Reliability Study.

Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review (2023)
Journal Article
O’Sullivan, O., Ladlow, P., Steiner, K., Kuyser, D., Ali, O., Stocks, J., …Kluzek, S. (2023). Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review. Osteoarthritis and Cartilage Open, 5(3), Article 100385. https://doi.org/10.1016/j.ocarto.2023.100385

Introduction
Osteoarthritis (OA) results from various aetiologies, including joint morphology, biomechanics, inflammation, and injury. The latter is implicated in post-traumatic OA, which offers a paradigm to identify potential biomarkers enabling e... Read More about Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review.

Osteoarthritis in the UK Armed Forces: a review of its impact, treatment and future research (2023)
Journal Article
O'Sullivan, O., Behan, F. P., Coppack, R. J., Stocks, J., Kluzek, S., Valdes, A. M., & Bennett, A. N. (2024). Osteoarthritis in the UK Armed Forces: a review of its impact, treatment and future research. BMJ Military Health, 170(4), 359-364. https://doi.org/10.1136/military-2023-002390

Within the UK Armed Forces, musculoskeletal injuries account for over half of all medical downgrades and discharges. Data from other Armed Forces show that osteoarthritis (OA), more common in military personnel, is likely to contribute to this, both... Read More about Osteoarthritis in the UK Armed Forces: a review of its impact, treatment and future research.

Return to performance following severe ankle, knee, and hip injuries in National Basketball Association players (2022)
Journal Article
Bullock, G. S., Ferguson, T., Arundale, A. H., Martin, C. L., Collins, G. S., & Kluzek, S. (2022). Return to performance following severe ankle, knee, and hip injuries in National Basketball Association players. PNAS Nexus, 1(4), Article pgac176. https://doi.org/10.1093/pnasnexus/pgac176

The purpose of this study was to compare basketball performancemarkers 1 y prior to initial severe lower extremity injury, including ankle, knee, and hip injuries, to 1 and 2 y following injury during the regular National Basketball Association (NBA)... Read More about Return to performance following severe ankle, knee, and hip injuries in National Basketball Association players.

Response to Comment on: “Black Box Prediction Methods in Sports Medicine Deserve a Red Card for Reckless Practice: A Change of Tactics is Needed to Advance Athlete Care” (2022)
Journal Article
Bullock, G. S., Hughes, T., Arundale, A. H., Ward, P., Collins, G. S., & Kluzek, S. (2022). Response to Comment on: “Black Box Prediction Methods in Sports Medicine Deserve a Red Card for Reckless Practice: A Change of Tactics is Needed to Advance Athlete Care”. Sports Medicine, 52, 2799-2801. https://doi.org/10.1007/s40279-022-01737-5

Assessment of Fatigue and Recovery in Sport: Narrative Review (2022)
Journal Article
Bestwick-Stevenson, T., Toone, R., Neupert, E., Edwards, K., & Kluzek, S. (2022). Assessment of Fatigue and Recovery in Sport: Narrative Review. International Journal of Sports Medicine, 43(14), 1151-1162. https://doi.org/10.1055/a-1834-7177

Fatigue is a phenomenon associated with decreases in both physical and cognitive performances and increases in injury occurrence. Competitive athletes are required to complete demanding training programs with high workloads to elicit the physiologica... Read More about Assessment of Fatigue and Recovery in Sport: Narrative Review.

Impact of three different phases of UK Covid-19 lockdown restrictions, Covid infections and Covid vaccination status on runners training distance and pace (2022)
Presentation / Conference Contribution
Stocks, J., Bullock, G. S., Feakins, B., Gayer De Mena, L., Tahir, D., Zheng, J., Wang, S., Huang, X., Bestwick-Stevenson, T., Jumbu, N., Simpkins, D., & Kluzek, S. (2022, May). Impact of three different phases of UK Covid-19 lockdown restrictions, Covid infections and Covid vaccination status on runners training distance and pace. Poster presented at BASEM 2022 Conference, Brighton, UK

Common Joint Pain In The Running Community (2022)
Presentation / Conference Contribution
Stocks, J., Bullock, G. S., & Kluzek, S. (2022, April). Common Joint Pain In The Running Community. Poster presented at Pain in Europe XII: 12th Congress of the European Pain Federation EFIC, Dublin, Ireland

Temporal trends in incidence of time-loss injuries in four male professional North American sports over 13 seasons (2021)
Journal Article
Bullock, G. S., Murray, E., Vaughan, J., & Kluzek, S. (2021). Temporal trends in incidence of time-loss injuries in four male professional North American sports over 13 seasons. Scientific Reports, 11, Article 8278. https://doi.org/10.1038/s41598-021-87920-6

Sports-related injuries increase healthcare cost burden, and in some instances have harmful long term physical and psychological implications. There is currently a lack of comprehensive data on temporal injury trends across professional North America... Read More about Temporal trends in incidence of time-loss injuries in four male professional North American sports over 13 seasons.

Physical inactivity and health inequality during coronavirus: a novel opportunity or total lockdown? (2020)
Journal Article
Shur, N., Johns, . D., Kluzek, S., & Peirce, N. (2020). Physical inactivity and health inequality during coronavirus: a novel opportunity or total lockdown?. BMJ Open Sport and Exercise Medicine, 6(1), Article e000903. https://doi.org/10.1136/bmjsem-2020-000903

Government-restricted movement during the coronavirus pandemic in various countries around the world has led to rapid and fundamental changes in our health behaviour. As well as being at a higher risk of contracting and being hospitalised with COVID-... Read More about Physical inactivity and health inequality during coronavirus: a novel opportunity or total lockdown?.

Quantitative and Semi-Quantitative Assessment of Synovitis on MRI and the Relationship with Symptoms in Symptomatic Knee Osteoarthritis (2020)
Journal Article
Perry, T., Yang, X., van Santen, J., Arden, N., & Kluzek, S. (2021). Quantitative and Semi-Quantitative Assessment of Synovitis on MRI and the Relationship with Symptoms in Symptomatic Knee Osteoarthritis. Journal of Rheumatology, 60(4), 1763-1773. https://doi.org/10.1093/rheumatology/keaa619

Objectives: Synovitis in symptomatic knee osteoarthritis (KOA) is common and is associated with joint symptoms. Optimal synovial measurement on magnetic resonance imaging (MRI) is however, unclear. Our aims were to examine the relationship between MR... Read More about Quantitative and Semi-Quantitative Assessment of Synovitis on MRI and the Relationship with Symptoms in Symptomatic Knee Osteoarthritis.

Current management strategies in Osgood Schlatter: A cross-sectional mixed-method study (2020)
Journal Article
Lyng, K. D., Rathleff, M. S., Dean, B. J. F., Kluzek, S., & Holden, S. (2020). Current management strategies in Osgood Schlatter: A cross-sectional mixed-method study. Scandinavian Journal of Medicine and Science in Sports, 30(10), 1985-1991. https://doi.org/10.1111/sms.13751

Background: Osgood Schlatter disease (OSD) is the most common knee condition in adolescent athletes aged 9-16. Without evidence to guide clinical practice, it is unclear how OSD is managed. The aim of this study was to investigate how international h... Read More about Current management strategies in Osgood Schlatter: A cross-sectional mixed-method study.

The presentation, diagnosis and management of non-traumatic wrist pain: an evaluation of current practice in secondary care in the UK NHS (2020)
Journal Article
Dean, B. J., Carr, A., Trickett, R. W., Kluzek, S., Riley, N., Bretherton, C. P., …Cheng, C. (2020). The presentation, diagnosis and management of non-traumatic wrist pain: an evaluation of current practice in secondary care in the UK NHS. Rheumatology Advances in Practice, 4(2), Article rkaa030. https://doi.org/10.1093/rap/rkaa030

Objectives. The study aims were to assess the burden of non-traumatic wrist pain in terms of numbers of referrals to secondary care and to characterize how patients present, are diagnosed and are managed in secondary care in the UK National Health Se... Read More about The presentation, diagnosis and management of non-traumatic wrist pain: an evaluation of current practice in secondary care in the UK NHS.

The presentation, diagnosis and management of non-traumatic wrist pain: an evaluation of current practice in secondary care in the UK NHS (2020)
Journal Article
Dean, B. J., Carr, A., Trickett, R. W., Kluzek, S., Riley, N., Bretherton, C. P., …As-Sultany, M. (2020). The presentation, diagnosis and management of non-traumatic wrist pain: an evaluation of current practice in secondary care in the UK NHS. Rheumatology Advances in Practice, 4(2), Article rkaa030. https://doi.org/10.1093/rap/rkaa030

Abstract
Objectives
The study aims were to assess the burden of non-traumatic wrist pain in terms of numbers of referrals to secondary care, and to characterise how patients present, are diagnosed and are managed in secondary care in the United Kin... Read More about The presentation, diagnosis and management of non-traumatic wrist pain: an evaluation of current practice in secondary care in the UK NHS.

Pain trajectory defines knee osteoarthritis subgroups: a prospective observational study (2020)
Journal Article
Radojčić, M. R., Arden, N. K., Yang, X., Strauss, V. Y., Birrell, F., Cooper, C., …VIDEO Trial Investigators. (2020). Pain trajectory defines knee osteoarthritis subgroups: a prospective observational study. PAIN, 161(12), 2841-2851. https://doi.org/10.1097/j.pain.0000000000001975

Knee osteoarthritis (OA) is a heterogeneous disease, and identification of its subgroups/phenotypes can improve patient treatment and drug development. We aimed to identify homogeneous OA subgroups/phenotypes using pain development over time; to unde... Read More about Pain trajectory defines knee osteoarthritis subgroups: a prospective observational study.

Conservative management of fifth metacarpal head fracture in a professional cricketer: A case study and literature review (2020)
Journal Article
Pandya, T., Dale, S., Donnison, E., & Kluzek, S. (2020). Conservative management of fifth metacarpal head fracture in a professional cricketer: A case study and literature review. Clinical Case Reports, 8(9), 1682-1685. https://doi.org/10.1002/ccr3.2960

Diagnosis of fifth metacarpal head fracture with collateral ligament injuries can be difficult. We present a case of a professional cricketer with a fifth metacarpal head fracture. who played a match before pain made the injury obvious. Following im... Read More about Conservative management of fifth metacarpal head fracture in a professional cricketer: A case study and literature review.

Symptomatic stress reaction of the humerus in a professional cricketer (2019)
Journal Article
Beech, M., Nagra, N. S., Wedatilake, T., & Kluzek, S. (2019). Symptomatic stress reaction of the humerus in a professional cricketer. BMJ Case Reports, 12(9), Article e227088. https://doi.org/10.1136/bcr-2018-227088

A symptomatic bone stress reaction is an early pathological feature, which can lead to stress fractures. It typically affects bones of the lower limbs in response to unaccustomed disproportional compressive loading. Professional sportspeople are susc... Read More about Symptomatic stress reaction of the humerus in a professional cricketer.

Machine-learning for osteoarthritis research (2019)
Journal Article
Kluzek, S., & Mattei, T. (2019). Machine-learning for osteoarthritis research. Osteoarthritis and Cartilage, 27(7), 977-978. https://doi.org/10.1016/j.joca.2019.04.005

Machine learning (ML) algorithms have the ability to automatically learn and improve from experience without being specifically directed. There has been great optimism that such techniques may improve scientific biomedical research in several fields1... Read More about Machine-learning for osteoarthritis research.

Interleukin-17 is a potential contributor to the inflammatory environment in the OA joint (2019)
Presentation / Conference Contribution
Mimpen, J., Kluzek, S., Price, A., Snelling, S., Watt, F., Dakin, S., & Carr, A. (2019). Interleukin-17 is a potential contributor to the inflammatory environment in the OA joint. Osteoarthritis and Cartilage, 27(S1), S379. https://doi.org/10.1016/j.joca.2019.02.377+showArticle+Info

Purpose: Osteoarthritis (OA) has been historically viewed as a degenerative disease caused by ‘wear and tear’, with the loss of articular cartilage as the most important clinical feature. Modern imaging techniques have shown us over the last decade t... Read More about Interleukin-17 is a potential contributor to the inflammatory environment in the OA joint.

Risk of Injury in Royal Air Force Training: Does Sex Really Matter? (2018)
Journal Article
Fallowfield, J. L., Leiper, R. G., Shaw, A. M., Whittamore, D. R., Lanham-New, S. A., Allsopp, A. J., …Sanchez-Santos, M. T. (2020). Risk of Injury in Royal Air Force Training: Does Sex Really Matter?. Military Medicine, 185(1-2), 170–177. https://doi.org/10.1093/milmed/usy177

Introduction

Musculoskeletal injuries are common during military and other occupational physical training programs. Employers have a duty of care to reduce employees’ injury risk, where females tend to be at greater risk than males. However, quant... Read More about Risk of Injury in Royal Air Force Training: Does Sex Really Matter?.

Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review (2018)
Journal Article
Cairns, G., Owen, T., Kluzek, S., Thurley, N., Holden, S., Rathleff, M. S., & Dean, B. J. F. (2018). Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review. BMJ Open Sport and Exercise Medicine, 4(1), Article e000383. https://doi.org/10.1136/bmjsem-2018-000383

Objective: Evaluate effectiveness and harms of interventions for patellar tendon related pain in children and adolescents.

Design: Systematic review and meta-analysis.

Data sources: Medline via Pubmed, Embase via OVID, CINAHL via Ebsco, SportDi... Read More about Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review.

Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women (2018)
Journal Article
Sanchez-Santos, M., Judge, A., Gulati, M., Spector, T., Hart, D., Newton, J., …Kluzek, S. (2019). Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women. Seminars in Arthritis and Rheumatism, 48(5), 791-798. https://doi.org/10.1016/j.semarthrit.2018.07.007

Objective

It is unclear whether the association between osteoarthritis (OA) and metabolic syndrome (MetS) varies with the site of the affected joint and the presence of pain. Our aim was to describe the association between MetS and radiographic OA... Read More about Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women.

Partial mid-portion Achilles tear resulting in substantial improvement in pain and function in an amateur long-distance runner (2018)
Journal Article
Woyton, M. M., Kluzek, S., Wedatilake, T., & Davies, M. A. M. (2018). Partial mid-portion Achilles tear resulting in substantial improvement in pain and function in an amateur long-distance runner. BMJ Case Reports, 2018, Article bcr-2018-225823. https://doi.org/10.1136/bcr-2018-225823

This case presents symptom resolution for a long-distance runner with chronic Achilles tendinopathy (AT), following a partial tear of his Achilles tendon. The patient reported a sudden pain during a morning run, with preserved function. Three hours p... Read More about Partial mid-portion Achilles tear resulting in substantial improvement in pain and function in an amateur long-distance runner.

Confusion and abdominal symptoms following a rugby tackle (2017)
Journal Article
Ioannides, D., Davies, M., & Kluzek, S. (2017). Confusion and abdominal symptoms following a rugby tackle. BMJ Case Reports, 2017, Article bcr-2017-222160. https://doi.org/10.1136/bcr-2017-222160

A 19-year-old man was sent to the emergency department following a pitch-side assessment for suspected concussion, unexplained upper abdominal tenderness and vomiting, following a high-impact tackle during a rugby match. A Focussed Assessment with So... Read More about Confusion and abdominal symptoms following a rugby tackle.

A large chronic pericardial effusion in an ultramarathon runner with anti-CCP positive rheumatoid arthritis (2017)
Journal Article
McClelland, T. J., Penfold, R., Kluzek, S., & Nagra, N. S. (2017). A large chronic pericardial effusion in an ultramarathon runner with anti-CCP positive rheumatoid arthritis. BMJ Case Reports, 2017, Article bcr-2017-219350. https://doi.org/10.1136/bcr-2017-219350

Pericardial effusions arise as an extra-articular manifestation of rheumatoid arthritis (RA). Pericardial effusions are often asymptomatic, particularly in the early phase, but patients are at risk of cardiac tamponade as the effusion progresses. We... Read More about A large chronic pericardial effusion in an ultramarathon runner with anti-CCP positive rheumatoid arthritis.

Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy (2016)
Journal Article
Wallace, G., Cro, S., Doré, C., King, L., Kluzek, S., Price, A., …Arden, N. (2017). Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy. Arthritis Care and Research, 69(9), 1340-1348. https://doi.org/10.1002/acr.23162

Objective

Painful knee osteoarthritis (KOA) has been associated with joint inflammation. There is, however, little literature correlating signs of localized inflammation with contrast‐enhanced (CE) magnetic resonance imaging (MRI) of synovium. Thi... Read More about Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross-Sectional Substudy.

Markers of synovial inflammation in cohorts at risk of knee osteoarthritis (2016)
Thesis
Kluzek, S. (2016). Markers of synovial inflammation in cohorts at risk of knee osteoarthritis. (Thesis). University of Oxford. Retrieved from https://nottingham-repository.worktribe.com/output/4471293

Background and objectives. Knee osteoarthritis (KOA) is a leading cause of disability in the developed world. Additionally, it is possibly linked with premature mortality. Low-grade inflammation is associated with a high risk of non-traumatic KOA inc... Read More about Markers of synovial inflammation in cohorts at risk of knee osteoarthritis.

Suprapatellar synovial hypertrophy and reliability of the novel ultrasound assessment of suprapatellar recess in patients with recent knee injuries or early osteoarthritis (2016)
Presentation / Conference Contribution
Kluzek, S., Wedatilake, T., McNally, E., Price, A., Judge, A., Watt, F., …Newton, J. (2016). Suprapatellar synovial hypertrophy and reliability of the novel ultrasound assessment of suprapatellar recess in patients with recent knee injuries or early osteoarthritis. Osteoarthritis and Cartilage, 24(S1), S299-S300. https://doi.org/10.1016/j.joca.2016.01.545

Purpose: Early through to late stage knee osteoarthritis (KOA) has been linked with effusion-synovitis in the suprapatellar pouch and chronic inflammation has been particularly associated with pain. Recent studies also suggest that synovial hypertrop... Read More about Suprapatellar synovial hypertrophy and reliability of the novel ultrasound assessment of suprapatellar recess in patients with recent knee injuries or early osteoarthritis.

Response to: ‘Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women’ by Gao et al (2016)
Journal Article
Kluzek, S., Sanchez-Santos, M. T., Leyland, K. M., Judge, A., Newton, J., & Arden, N. K. (2016). Response to: ‘Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women’ by Gao et al. Annals of the Rheumatic Diseases, 75(4), Article e23. https://doi.org/10.1136/annrheumdis-2015-209029

Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women (2015)
Journal Article
Kluzek, S., Bay-Jensen, A.-C., Judge, A., Karsdal, M. A., Shorthose, M., Spector, T., …Arden, N. K. (2015). Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women. Biomarkers, 20(8), 557-564. https://doi.org/10.3109/1354750x.2015.1105498

Context and objective: We evaluated the predictive value of serum cartilage oligomeric matrix protein (sCOMP) levels over 20 years on the development of radiographic (RKOA) and painful knee osteoarthritis (KOA) in a longitudinal cohort of middle-aged... Read More about Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women.

Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women (2015)
Journal Article
Kluzek, S., Sanchez-Santos, M. T., Leyland, K. M., Judge, A., Spector, T. D., Hart, D., …Arden, N. K. (2016). Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women. Annals of the Rheumatic Diseases, 75(10), 1749-1756. https://doi.org/10.1136/annrheumdis-2015-208056

To assess whether joint pain or radiographic osteoarthritis (ROA) of the knee and hand is associated with all-cause and disease-specific mortality in middle-aged women.

Methods: Four subgroups from the prospective community-based Chingford Cohort... Read More about Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women.

Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis (2015)
Journal Article
Williamson, W., Kluzek, S., Roberts, N., Richards, J., Arden, N., Leeson, P., …Foster, C. (2015). Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis. BMJ Open, 5(8), Article e007642. https://doi.org/10.1136/bmjopen-2015-007642

Objective: To assess effectiveness of osteoarthritis interventions to promote long-term physical activity behaviour change.

Design: A systematic review and meta-analysis. Protocol registration PROSPERO CRD4201300444 5 (http://www.crd.york.ac.uk/pr... Read More about Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis.

Is osteoarthritis a metabolic disorder? (2015)
Journal Article
Kluzek, S., Newton, J. L., & Arden, N. K. (2015). Is osteoarthritis a metabolic disorder?. British Medical Bulletin, 115(1), 111-121. https://doi.org/10.1093/bmb/ldv028

Background

Obesity is associated with an increased risk of developing osteoarthritis (OA), even in non-weight bearing joints. High levels of adipose tissue-associated inflammation may explain this association.

Sources of data and areas of debat... Read More about Is osteoarthritis a metabolic disorder?.

Adipokines as potential prognostic biomarkers in patients with acute knee injury (2015)
Journal Article
Kluzek, S., Arden, N. K., & Newton, J. (2015). Adipokines as potential prognostic biomarkers in patients with acute knee injury. Biomarkers, 20(8), 519-525. https://doi.org/10.3109/1354750x.2014.948914

This review considers adipokines as predictive biomarkers for early onset post-traumatic knee osteoarthritis (KOA). Serum concentrations of leptin and resistin can predict radiographic changes and are elevated in early KOA, with higher leptin concent... Read More about Adipokines as potential prognostic biomarkers in patients with acute knee injury.

Acute compartment syndrome of the thigh in a rugby player (2015)
Journal Article
Smith, R. D. J., Rust-March, H., & Kluzek, S. (2015). Acute compartment syndrome of the thigh in a rugby player. BMJ Case Reports, 2015, Article bcr2015210856. https://doi.org/10.1136/bcr-2015-210856

In the absence of obvious trauma, diagnosis of acute compartment syndrome (ACS) of the thigh can easily be delayed, as disproportional pain is not always present. We present a case of ACS of the anterior right thigh compartment in a healthy, semiprof... Read More about Acute compartment syndrome of the thigh in a rugby player.

The relationship between the significant knee and hip pain and use of non-steroid medication in the middle-aged and elderly UK running population: large cohort study
Presentation / Conference Contribution
Kluzek, S., Bullock, G. S., Bestwick-Stevenson, T., & Stocks, J. (2022, March). The relationship between the significant knee and hip pain and use of non-steroid medication in the middle-aged and elderly UK running population: large cohort study. Presented at WCO-IOF-ESCEO Congress 2022. World Congress on Osteoporosis, Osteoarthritis and Musculosketal Diseases, Virtual

Objectives Oral anti-inflammatory non-steroidal drugs (NSAID) are used commonly in the general population. Association between knee osteoarthritis (OA) and early cardiovascular mortality is often linked with decreased physical activity. Both running... Read More about The relationship between the significant knee and hip pain and use of non-steroid medication in the middle-aged and elderly UK running population: large cohort study.

The relationship of lower extremity persistent pain and osteoarthritis on running and physical activity in recreational runners: large prospective cohort study (Running Through)
Presentation / Conference Contribution
Bullock, G. S., Stocks, J., Feakins, B., Bestwick-Stevenson, T., & Kluzek, S. (2022, April). The relationship of lower extremity persistent pain and osteoarthritis on running and physical activity in recreational runners: large prospective cohort study (Running Through). Presented at OARSI 2022 World Congress on Osteoarthritis, Berlin, Germany