Outputs (11)

Role of drugs used for chronic disease management on susceptibility and severity of COVID-19: A large case-control study (2020)
Journal Article
Yan, H., Valdes, A. M., Vijay, A., Wang, S., Liang, L., Yang, S., …Aithal, G. P. (2020). Role of drugs used for chronic disease management on susceptibility and severity of COVID-19: A large case-control study. Clinical Pharmacology and Therapeutics, 108(6), 1185-1194. https://doi.org/10.1002/cpt.2047

The study aimed to investigate whether specific medications used in the treatment chronic diseases affected either the development and/ or severity of COVID-19 in a cohort of 610 COVID-19 cases and 48,667 population-based controls from Zheijang, Chin... Read More about Role of drugs used for chronic disease management on susceptibility and severity of COVID-19: A large case-control study.

The East Midlands Knee Pain Multiple Randomised Controlled Trial Cohort Study: Cohort Establishment and Feasibility study protocol (2020)
Journal Article
Hall, M. C., Fuller, A., Nomikos, P. A., Millar, B., Ogollah, R., Valdes, A., …Abhishek, A. (2020). The East Midlands Knee Pain Multiple Randomised Controlled Trial Cohort Study: Cohort Establishment and Feasibility study protocol. BMJ Open, 10(9), Article e037760

Introduction: Knee pain and osteoarthritis (OA) are a common cause of disability. The UK National Institute of Health and Care Excellence (NICE) OA guidelines recommend education, exercise and weight-loss advice (if overweight) as core interventions... Read More about The East Midlands Knee Pain Multiple Randomised Controlled Trial Cohort Study: Cohort Establishment and Feasibility study protocol.

East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol (2020)
Journal Article
Hall, M., Fuller, A., Nomikos, P. A., Millar, B., Ogollah, R., Valdes, A., …Abhishek, A. (2020). East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol. BMJ Open, 10(9), https://doi.org/10.1136/bmjopen-2020-037760

© 2020 BMJ Open Introduction Knee pain due to osteoarthritis (OA) is a common cause of disability. The UK National Institute for Health and Care Excellence OA guidelines recommend education, exercise and weight loss advice (if overweight) as core int... Read More about East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol.

Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes (2020)
Journal Article
Menni, C., Zhu, J., Le Roy, C. I., Mompeo, O., Young, K., Rebholz, C. M., …Valdes, A. M. (2020). Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes. Gut Microbes, 11(6), 1632-1642. https://doi.org/10.1080/19490976.2020.1778261

Type 2 diabetes (T2D) is associated with reduced gut microbiome diversity, although the cause is unclear. Metabolites generated by gut microbes also appear to be causative factors in T2D. We therefore searched for serum metabolites predictive of gut... Read More about Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes.

Human postprandial responses to food and potential for precision nutrition (2020)
Journal Article
Berry, S. E., Valdes, A. M., Drew, D. A., Asnicar, F., Mazidi, M., Wolf, J., …Spector, T. D. (2020). Human postprandial responses to food and potential for precision nutrition. Nature Medicine, https://doi.org/10.1038/s41591-020-0934-0

Real-time tracking of self-reported symptoms to predict potential COVID-19 (2020)
Journal Article
Menni, C., Valdes, A. M., Freidin, M. B., Sudre, C. H., Nguyen, L. H., Drew, D. A., …Spector, T. D. (2020). Real-time tracking of self-reported symptoms to predict potential COVID-19. Nature Medicine, 26, 1037-1040. https://doi.org/10.1038/s41591-020-0916-2

A total of 2,618,862 participants reported their potential symptoms of COVID-19 on a smartphone-based app. Among the 18,401 who had undergone a SARS-CoV-2 test, the proportion of participants who reported loss of smell and taste was higher in those w... Read More about Real-time tracking of self-reported symptoms to predict potential COVID-19.

Mediators of the predictive relationship between a self-report measure of central mechanisms and future knee pain outcomes in the knee pain in the community (KPIC) cohort (2020)
Conference Proceeding
Matthews, R., Akin-Akinyosoye, K., Frowd, N., Swaithes, L., Stocks, J., Sarmanova, A., …Walsh, D. A. (2020). Mediators of the predictive relationship between a self-report measure of central mechanisms and future knee pain outcomes in the knee pain in the community (KPIC) cohort.

Pain distant from the index site and sensitization in people with knee pain and low back pain (2020)
Conference Proceeding
Akin-Akinyosoye, K., Georgopoulos, V., Frowd, N., Swaithes, L., Stocks, J., Fernandes, G. S., …Walsh, D. (2020). Pain distant from the index site and sensitization in people with knee pain and low back pain.

Investigating musculoskeletal health and wellbeing; A cohort study protocol (2020)
Journal Article
Millar, B., McWilliams, D. F., Abhishek, A., Akin-Akinyosoye, K., Auer, D. P., Chapman, V., …Walsh, D. A. (2020). Investigating musculoskeletal health and wellbeing; A cohort study protocol. BMC Musculoskeletal Disorders, 21(1), Article 182. https://doi.org/10.1186/s12891-020-03195-4

© 2020 The Author(s). Background: In an ageing population, pain, frailty and disability frequently coexist across a wide range of musculoskeletal diagnoses, but their associations remain incompletely understood. The Investigating Musculoskeletal Heal... Read More about Investigating musculoskeletal health and wellbeing; A cohort study protocol.

Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI (2020)
Journal Article
Iwabuchi, S. J., Xing, Y., Cottam, W. J., Drabek, M. M., Tadjibaev, A., Fernandes, G. S., …Auer, D. P. (2020). Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI. PAIN, 161(6), 1255-1263. https://doi.org/10.1097/j.pain.0000000000001829

Chronic musculoskeletal pain is a common problem globally. Current evidence suggests that maladapted central pain pathways are associated with pain chronicity, for example, in postoperative pain after knee replacement. Other factors such as low mood,... Read More about Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI.

The Evaluation and Use of a Food Frequency Questionnaire Among the Population in Trivandrum, South Kerala, India (2020)
Journal Article
Vijay, A., Mohan, L., Taylor, M. A., Grove, J. I., Valdes, A. M., Aithal, G. P., & Shenoy, K. T. (2020). The Evaluation and Use of a Food Frequency Questionnaire Among the Population in Trivandrum, South Kerala, India. Nutrients, 12(2), https://doi.org/10.3390/nu12020383

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dietary record tools such as food frequency questionnaire (FFQ) and food diaries (FD) are the most commonly used choices for assessing dietary intakes in most large-scale epidemiological studi... Read More about The Evaluation and Use of a Food Frequency Questionnaire Among the Population in Trivandrum, South Kerala, India.