Outputs (68)

When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial) (2024)
Journal Article
Brown, S., Ploeger, C., Guo, B., Petersen, J. J., Beckenstrom, A. C., Browning, M., …Morriss, R. (2024). When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial). Comprehensive Psychiatry, 132, Article 152467. https://doi.org/10.1016/j.comppsych.2024.152467

Background A RCT of a novel intervention to detect antidepressant medication response (the PReDicT Test) took place in five European countries, accompanied by a nested study of its acceptability and implementation presented here. The RCT results i... Read More about When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial).

The impact of the COVID-19 pandemic on children and adolescent mental health inpatient service use in England: An interrupted time-series analysis of national patient records (2024)
Journal Article
Tsiachristas, A., Holland, J., Guo, B., Chitsabesan, P., Sayal, K., & Pari, A. A. A. (2024). The impact of the COVID-19 pandemic on children and adolescent mental health inpatient service use in England: An interrupted time-series analysis of national patient records. BJPsych Open, 10(2), Article e69. https://doi.org/10.1192/bjo.2024.9

Background: During the initial phases of the COVID 19 pandemic children and young people (CYP) faced significant restrictions. The virus and mitigation approaches significantly impacted how health services could function, and be safely delivered.... Read More about The impact of the COVID-19 pandemic on children and adolescent mental health inpatient service use in England: An interrupted time-series analysis of national patient records.

Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences (2024)
Journal Article
Patel, P., Brown, S., Guo, B., Holmes, E. A., Iyadurai, L., Kingslake, J., …Morriss, R. (2024). Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences. JMIR Formative Research, 8(1), Article e47458. https://doi.org/10.2196/47458

Background: Many intensive care unit (ICU) staff experience intrusive memories following work-related traumatic events, which can lead to long-term mental health outcomes and impact work functioning. There is a need for interventions that target intr... Read More about Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences.

'Far Away from Home': adolescent inpatient admissions far from home, out of area or to adult wards: a national surveillance study. (2023)
Journal Article
Holland, J., Roe, J., Guo, B., Dasilva-Ellimah, M., Burn, A., Dubicka, B., …Sayal, K. (2023). 'Far Away from Home': adolescent inpatient admissions far from home, out of area or to adult wards: a national surveillance study. BMJ Mental Health, 26(1), Article e300843. https://doi.org/10.1136/bmjment-2023-300843

Background The increasing prevalence and acuity of mental disorders among children and adolescents have placed pressure on services, including inpatient care, and resulted in young people being admitted at-distance or to adult wards. Little empirical... Read More about 'Far Away from Home': adolescent inpatient admissions far from home, out of area or to adult wards: a national surveillance study..

Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months (2023)
Journal Article
Nixon, N., Guo, B., Kaylor-Hughes, C., Simpson, S., Garland, A., Dalgleish, T., & Morriss, R. (2024). Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months. Journal of Affective Disorders, 345, 70-77. https://doi.org/10.1016/j.jad.2023.10.105

Background: Despite the known health costs of persistent depression, there is no established service framework for the treatment of this disorder and a lack of long-term outcome data to inform commissioning. To address this gap, we report the long-te... Read More about Specialist treatment for persistent depression in secondary care: Sustained effects from a multicentre UK study at 24 and 36 months.

Clinical Perspectives on Using Remote Measurement Technology in Assessing Epilepsy, Multiple Sclerosis, and Depression: Delphi Study (2023)
Journal Article
Andrews, J. A., Craven, M. P., Guo, B., Weyer, J., Lees, S., Zormpas, S. I., …RADAR-CNS Consortium. (2023). Clinical Perspectives on Using Remote Measurement Technology in Assessing Epilepsy, Multiple Sclerosis, and Depression: Delphi Study. JMIR Neurotechnology, 2, Article e41439. https://doi.org/10.2196/41439

Background: Multiple sclerosis (MS), epilepsy, and depression are chronic central nervous system conditions in which remote measurement technology (RMT) may offer benefits compared with usual assessment. We previously worked with clinicians, patients... Read More about Clinical Perspectives on Using Remote Measurement Technology in Assessing Epilepsy, Multiple Sclerosis, and Depression: Delphi Study.

Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial (2023)
Journal Article
Morriss, R., Patel, S., Boutry, C., Patel, P., Guo, B., Briley, P. M., …Kai, J. (2023). Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial. Lancet Psychiatry, 10(3), 172-183. https://doi.org/10.1016/S2215-0366%2823%2900007-X

Background: Randomised sham-controlled trials of cranial electrostimulation with the Alpha-Stim Anxiety Insomnia and Depression (AID) device have reported improved anxiety and depression symptoms; however, no adequately powered sham-controlled trials... Read More about Clinical effectiveness of active Alpha-Stim AID versus sham Alpha-Stim AID in major depression in primary care in England (Alpha-Stim-D): a multicentre, parallel group, double-blind, randomised controlled trial.

A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study (2022)
Journal Article
Lee, A. R., McDermott, O., Guo, B., Roe, J., & Orrell, M. (2022). A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study. JMIR Research Protocols, 11(7), Article e33881. https://doi.org/10.2196/33881

Background: With the rapid increase in the prevalence of dementia in the United Kingdom and beyond, the emotional, social, and economic burden on individuals, families, and health care services continues to rise. Currently, interventions that enable... Read More about A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study.

Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals (2022)
Journal Article
Andrews, J. A., Craven, M. P., Lang, A. R., Guo, B., Morriss, R., Hollis, C., & RADAR-CNS Consortium. (2022). Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals. BMC Medical Informatics and Decision Making, 22(1), Article 125. https://doi.org/10.1186/s12911-022-01856-z

BACKGROUND: Epilepsy, multiple sclerosis(MS) and depression are long term, central nervous system disorders which have a significant impact on everyday life. Evaluating symptoms of these conditions is problematic and typically involves repeated visit... Read More about Making remote measurement technology work in multiple sclerosis, epilepsy and depression: survey of healthcare professionals.

A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial) (2022)
Journal Article
Patel, S., Boutry, C., Patel, P., Craven, M. P., Guo, B., Zafar, A., …Morriss, R. (2022). A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial). Trials, 23(1), Article 250. https://doi.org/10.1186/s13063-022-06192-1

Background: Major depression is the second leading cause of years lost to disability worldwide and is a leading contributor to suicide. However, first-line antidepressants are only fully effective for 33%, and only 40% of those offered psychological... Read More about A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial).

Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey (2022)
Journal Article
Roe, J., Cresswell, A., Mittal, S., Al-Uzri, M., Tanner, J., Moore, M., …Morriss, R. (2022). Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey. Journal of Mental Health, 31(5), 724-731. https://doi.org/10.1080/09638237.2021.2022614

Clinical guidelines for mental health disorders produced by the National Institute of Care Excellence (NICE) emphasise a recovery-based approach clinical care with collaborative decision-making. The aim of the study was to explore service user experi... Read More about Service user experiences of care recommendations from the 2014 NICE guideline for bipolar disorder: a survey.

Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit (2022)
Journal Article
Coleston-Shields, D. M., Challis, D., Worden, A., Broome, E., Dening, T., Guo, B., …Orrell, M. (2022). Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit. Trials, 23, Article 54. https://doi.org/10.1186/s13063-021-05995-y

Background: Improving care at home for people with dementia is a core policy goal in the dementia strategies of many European countries. A challenge to effective home support is the occurrence of crises in the care of people with dementia which arise... Read More about Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): a study protocol for a randomised controlled trial of a Resource Kit.

The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey (2021)
Journal Article
Andrews, J. A., Craven, M. P., Lang, A. R., Guo, B., Morriss, R., Hollis, C., & The RADAR-CNS Consortium. (2021). The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey. BMC Medical Informatics and Decision Making, 21, Article 282. https://doi.org/10.1186/s12911-021-01640-5

Background: A variety of smartphone apps and wearables are available both to help patients monitor their health and to support health care professionals (HCPs) in providing clinical care. As part of the RADAR-CNS consortium, we have conducted researc... Read More about The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey.

Correction: A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial (2021)
Journal Article
Morriss, R., Kaylor-Hughes, C., Rawsthorne, M., Coulson, N., Simpson, S., Guo, B., …Williams, L. (2021). Correction: A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial. Journal of Medical Internet Research, 23(7), Article e31543. https://doi.org/10.2196/31543

[This corrects the article DOI: 10.2196/23487.].

The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time (2021)
Journal Article
Guo, B., Li, L., Crawford, M. J., & Morriss, R. (2021). The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time. International Journal of Methods in Psychiatric Research, 30(3), Article e1874. https://doi.org/10.1002/mpr.1874

Objectives There is a lack of independent longitudinal evidence on the factor structure and validity of the Zanarini Rating Scale for Borderline Personality Disorder (ZAN?BPD). This study aimed to investigate the dimensionality of ZAN?BPD and its... Read More about The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time.

Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., …Groom, M. J. (2021). Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 94. https://doi.org/10.1186/s40814-021-00830-2

A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial (2021)
Journal Article
Rawsthorne, M., Tata, L., Williams, L., Morriss, R., Guo, B., Simpson, S., …Moran, P. (2021). A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial. JMIR, 23(4), Article e23487. https://doi.org/10.2196/23487

Background: Effective help for depression and anxiety reaches a small proportion of people who might benefit from it. The scale of the problem suggests the need for effective, safe web-based public health services delivered directly to the public. On... Read More about A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial.

Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., …Groom, M. J. (2021). Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 68. https://doi.org/10.1186/s40814-021-00788-1

Background Medication for attention deficit hyperactivity disorder (ADHD) should be closely monitored to ensure optimisation. There is growing interest in using computerised assessments of ADHD symptoms to support medication monitoring. The aim of t... Read More about Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial.

The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial (2021)
Journal Article
Browning, M., Bilderbeck, A. C., Dias, R., Dourish, C. T., Kingslake, J., Deckert, J., …Dawson, G. R. (2021). The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial. Neuropsychopharmacology, 46, 1307–1314. https://doi.org/10.1038/s41386-021-00981-z

Depressed patients often do not respond to the first antidepressant prescribed, resulting in sequential trials of different medications. Personalised medicine offers a means of reducing this delay, however the clinical effectiveness of personalised a... Read More about The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial.

Pilot Randomised Evaluation of Singing in Dementia (PRESIDE): protocol for a two-arm, parallel group randomised controlled feasibility study with waiting-list control (2021)
Journal Article
Dowson, B., Schneider, J., Guo, B., Bath, P. M., Mcdermott, O., Haywood, L. J., & Orrell, M. (2021). Pilot Randomised Evaluation of Singing in Dementia (PRESIDE): protocol for a two-arm, parallel group randomised controlled feasibility study with waiting-list control. Pilot and Feasibility Studies, 7, Article 15. https://doi.org/10.1186/s40814-020-00759-y

Background As the number of people living with dementia grows, so does the need to provide them with adequate psychosocial support. Many people with dementia live at home with family carers, who also require social and emotional support to cope wi... Read More about Pilot Randomised Evaluation of Singing in Dementia (PRESIDE): protocol for a two-arm, parallel group randomised controlled feasibility study with waiting-list control.

Outcomes of a public health campaign and automated randomised controlled trial of a direct to public peer support programme (Big White Wall) versus web-based information to aid self-management of depression and anxiety (The REBOOT study) (2020)
Working Paper
Morriss, R., Kaylor-Hughes, C., Rawsthorne, M., Coulson, N., Simpson, S., Guo, B., …Williams, L. Outcomes of a public health campaign and automated randomised controlled trial of a direct to public peer support programme (Big White Wall) versus web-based information to aid self-management of depression and anxiety (The REBOOT study)

Background: Effective help for depression and anxiety only reaches a small proportion of those who might benefit from it. The scale of the problem suggests a role for effective, safe public health online services delivered directly to the public. On... Read More about Outcomes of a public health campaign and automated randomised controlled trial of a direct to public peer support programme (Big White Wall) versus web-based information to aid self-management of depression and anxiety (The REBOOT study).

The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome (2020)
Journal Article
Nixon, N., Guo, B., Garland, A., Kaylor-Hughes, C., Nixon, E., & Morriss, R. (2020). The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome. PLoS ONE, 15(10), Article e0241370. https://doi.org/10.1371/journal.pone.0241370

Background: The 17-item Hamilton Depression Rating Scale (HDRS17) is used world-wide as an observer-rated measure of depression in randomised controlled trials (RCTs) despite continued uncertainty regarding its factor structure. This study investiga... Read More about The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome.

Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study (2020)
Journal Article
Aldridge, Z., Patel, S., Guo, B., Nixon, E., Bouman, W. P., Witcomb, G. L., & Arcelus, J. (2021). Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study. Andrology, 9(6), 1808-1816. https://doi.org/10.1111/andr.12884

Background Cross-sectional studies show that transgender people are more likely than cisgender people to experience depression and anxiety before Gender Affirming Hormone Treatment (GAHT). However, the effect of GAHT on mental health in transgender... Read More about Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study.

Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study (2020)
Journal Article
Aldridge, Z., Patel, S., Guo, B., Nixon, E., Pierre Bouman, W., Witcomb, G. L., & Arcelus, J. (2021). Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study. Andrology, 9(6), 1808-1816. https://doi.org/10.1111/andr.12884

Background Cross?sectional studies show that transgender people are more likely than cisgender people to experience depression and anxiety before Gender Affirming Hormone Treatment (GAHT). However, the effect of GAHT on mental health in transgende... Read More about Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study.

How do patients spend their time in stroke rehabilitation units in England? The REVIHR study (2019)
Journal Article
Chouliara, N., Fisher, R., Crosbie, B., Guo, B., Sprigg, N., & Walker, M. (2021). How do patients spend their time in stroke rehabilitation units in England? The REVIHR study. Disability and Rehabilitation, 43(16), 2312-2319. https://doi.org/10.1080/09638288.2019.1697764

Aim: To examine how patients spend their time in stroke rehabilitation units in England. Methods: We recruited 144 patients within a month after stroke from four stroke rehabilitation units and observed their activity type, interactions and locati... Read More about How do patients spend their time in stroke rehabilitation units in England? The REVIHR study.

Meeting abstracts from the 5th International Clinical Trials Methodology Conference (ICTMC 2019) : Brighton, UK. 06-09 October 2019 (2019)
Presentation / Conference
Blake, H., Knox, E., Randell, T., Leighton, P., Guo, B., Greening, J., …Glazebrook, C. Meeting abstracts from the 5th International Clinical Trials Methodology Conference (ICTMC 2019) : Brighton, UK. 06-09 October 2019. Paper presented at Trials

SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus (2019)
Conference Proceeding
Blake, H., Knox, E., Randell, T., Leighton, P., Guo, B., Greening, J., …Glazebrook, C. (2019). SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus. In 5th International Clinical Trials Methodology Conference (ICTMC 2019) Book of Abstracts

Introduction: Physical activity is important for children with type 1 diabetes mellitus (T1DM) but it is unclear whether interventions delivered online are feasible, acceptable to patients and efficacious. The aim was to assess the feasibility and ac... Read More about SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus.

The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms (2019)
Journal Article
Hall, C. L., Guo, B., Valentine, A. Z., Groom, M. J., Daley, D., Sayal, K., & Hollis, C. (2019). The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms. PLoS ONE, 14(6), Article e0218518. https://doi.org/10.1371/journal.pone.0218518

Background: The Strengths and Difficulties Questionnaire (SDQ) is widely used to assess child and adolescent mental health problems. However, the factor structure of the SDQ is subject to debate and there is limited evidence investigating measurement... Read More about The validity of the Strengths and Difficulties Questionnaire (SDQ) for children with ADHD symptoms.

The Validity of the SNAP-IV in Children Displaying ADHD Symptoms (2019)
Journal Article
Hall, C. L., Guo, B., Valentine, A. Z., Groom, M. J., Daley, D., Sayal, K., & Hollis, C. (2020). The Validity of the SNAP-IV in Children Displaying ADHD Symptoms. Assessment, 27(6), 1258-1271. https://doi.org/10.1177/1073191119842255

The Swanson, Nolan, and Pelham Rating Scale (SNAP-IV) is a widely used scale that measures the core symptoms of attention deficit hyperactivity disorder (ADHD). However, there are contradictory findings regarding factor structure. Factor structure an... Read More about The Validity of the SNAP-IV in Children Displaying ADHD Symptoms.

SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus (2019)
Journal Article
Knox, E., Glazebrook, C., Randell, T., Leighton, P., Guo, B., Greening, J., …Blake, H. (2019). SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus. BMC Public Health, 19, 1-14. https://doi.org/10.1186/s12889-019-6697-1

Background: Physical activity and self-monitoring are important for children with type 1 diabetes mellitus (T1DM) but it is unclear whether interventions delivered online are feasible, acceptable to patients and efficacious. The aim was to assess the... Read More about SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus.

Feasibility of a randomised controlled trial of remotely delivered problem-solving cognitive behaviour therapy versus usual care for young people with depression and repeat self-harm: lessons learnt (e-DASH) (2019)
Journal Article
Sayal, K., Roe, J., Ball, H., Atha, C., Kaylor-Hughes, C., Guo, B., …Morriss, R. (2019). Feasibility of a randomised controlled trial of remotely delivered problem-solving cognitive behaviour therapy versus usual care for young people with depression and repeat self-harm: lessons learnt (e-DASH). BMC Psychiatry, 19(1), Article 42. https://doi.org/10.1186/s12888-018-2005-3

Background Self-harm and depression are strong risk factors for repeat self-harm and suicide. We aimed to investigate the feasibility of a randomised controlled trial (RCT) of remotely delivered problem-solving cognitive behaviour therapy (PSCBT)... Read More about Feasibility of a randomised controlled trial of remotely delivered problem-solving cognitive behaviour therapy versus usual care for young people with depression and repeat self-harm: lessons learnt (e-DASH).

Clinical and economic outcomes of remotely delivered cognitive behaviour therapy versus treatment as usual for repeat unscheduled care users with severe health anxiety: a multi-centre randomised controlled trial (2019)
Journal Article
Morriss, R., Patel, S., Mallins, S., Guo, B., Higton, F., James, M., …Tyrer, H. (2019). Clinical and economic outcomes of remotely delivered cognitive behaviour therapy versus treatment as usual for repeat unscheduled care users with severe health anxiety: a multi-centre randomised controlled trial. BMC Medicine, 17, 1-13. https://doi.org/10.1186/s12916-019-1253-5

Background: Repeat users of unscheduled health care with severe health anxiety are challenging to engage in psychological help and incur high service costs. We investigated whether clinical and economic outcomes were improved by offering remote cogni... Read More about Clinical and economic outcomes of remotely delivered cognitive behaviour therapy versus treatment as usual for repeat unscheduled care users with severe health anxiety: a multi-centre randomised controlled trial.

Evaluating the Care Certificate (ECCert): a cross-sector solution to assuring fundamental skills in caring (2018)
Report
Thomson, L., Argyle, E., Khan, Z., Schneider, J., Arthur, A., Maben, J., …Eve, J. (2018). Evaluating the Care Certificate (ECCert): a cross-sector solution to assuring fundamental skills in caring. Nottingham: Independent research

The effectiveness of exercise-based interventions for preventing or treating postpartum depression: a systematic review and meta-analysis (2018)
Journal Article
Carter, T., Bastounis, A., Guo, B., & Jane Morrell, C. (2019). The effectiveness of exercise-based interventions for preventing or treating postpartum depression: a systematic review and meta-analysis. Archives of Women's Mental Health, 22(1), 37-53. https://doi.org/10.1007/s00737-018-0869-3

© 2018, Springer-Verlag GmbH Austria, part of Springer Nature. Postpartum depression can have detrimental effects on both a mother’s physical and mental health and on her child’s growth and emotional development. The aim of this study is to assess th... Read More about The effectiveness of exercise-based interventions for preventing or treating postpartum depression: a systematic review and meta-analysis.

The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected attention deficit hyperactivity disorder: single-blind randomised controlled trial (2018)
Journal Article
the AQUA Trial Group, Hollis, C., Hall, C. L., Guo, B., James, M., Boadu, J., …Morriss, R. (2018). The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected attention deficit hyperactivity disorder: single-blind randomised controlled trial. Journal of Child Psychology and Psychiatry, 59(12), 1298-1308. https://doi.org/10.1111/jcpp.12921

© 2018 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health. Background: Diagnosis of attention deficit hyperactivity disorder (ADHD) relies on su... Read More about The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected attention deficit hyperactivity disorder: single-blind randomised controlled trial.

Supporting kids with diabetes in physical activity (2018)
Presentation / Conference
Knox, E. C., Glazebrook, C., Leighton, P., Randell, T., Greening, J., Guo, B., & Blake, H. (2018, March). Supporting kids with diabetes in physical activity. Paper presented at III Congreso Internacional en Investigacion y Didactica de la Educacion Fisica

Protocol investigating the clinical utility of an objective measure of attention, impulsivity and activity (QbTest) for optimising medication management in children and young people with ADHD ‘QbTest Utility for Optimising Treatment in ADHD’ (QUOTA): a feasibility randomised controlled trial (2018)
Journal Article
Hall, C. L., James, M., Brown, S., Martin, J. L., Brown, N., Selby, K., …Groom, M. J. (2018). Protocol investigating the clinical utility of an objective measure of attention, impulsivity and activity (QbTest) for optimising medication management in children and young people with ADHD ‘QbTest Utility for Optimising Treatment in ADHD’ (QUOTA): a feasibility randomised controlled trial. BMJ Open, 8(2), Article e021104. https://doi.org/10.1136/bmjopen-2017-021104

Introduction: Attention-deficit hyperactivity disorder (ADHD) is characterised by symptoms of inattention, hyperactivity and impulsivity. To improve outcomes, the National Institute for Health and Care Excellence ADHD guidelines recommend regular mon... Read More about Protocol investigating the clinical utility of an objective measure of attention, impulsivity and activity (QbTest) for optimising medication management in children and young people with ADHD ‘QbTest Utility for Optimising Treatment in ADHD’ (QUOTA): a feasibility randomised controlled trial.

Long-stay in forensic-psychiatric care in the UK (2018)
Journal Article
Hare Duke, L., Furtado, V., Guo, B., & Völlm, B. A. (in press). Long-stay in forensic-psychiatric care in the UK. Social Psychiatry and Psychiatric Epidemiology, https://doi.org/10.1007/s00127-017-1473-y

Purpose: Forensic services provide care for mentally disordered offenders. In England this is provided at three levels of security – low, medium and high. Significant number of patients within these settings remain detained for protracted periods of... Read More about Long-stay in forensic-psychiatric care in the UK.

Direct to Public Peer Support and e-Therapy Program Versus Information to Aid Self-Management of Depression and Anxiety: Protocol for a Randomized Controlled Trial (Preprint) (2017)
Other
Kaylor-Hughes, C. J., Rawsthorne, M., Coulson, N. S., Simpson, S., Simons, L., Guo, B., …REBOOT Notts Lived Experience Advisory Panel. (2017). Direct to Public Peer Support and e-Therapy Program Versus Information to Aid Self-Management of Depression and Anxiety: Protocol for a Randomized Controlled Trial (Preprint)

Direct to public peer support and e-therapy program versus information to aid self-management of depression and anxiety: protocol for a randomized controlled trial (2017)
Journal Article
Kaylor-Hughes, C., Rawsthorne, M., Coulson, N. S., Simpson, S., Simons, L., Guo, B., …Morriss, R. (in press). Direct to public peer support and e-therapy program versus information to aid self-management of depression and anxiety: protocol for a randomized controlled trial. Journal of Medical Internet Research, 6(12), Article e231. https://doi.org/10.2196/resprot.8061

Regardless of geography or income, effective help for depression and anxiety only reaches a small proportion of those who might benefit from it. The scale of the problem suggests a role for effective, safe, anonymised public health driven online serv... Read More about Direct to public peer support and e-therapy program versus information to aid self-management of depression and anxiety: protocol for a randomized controlled trial.

Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: An economic evaluation alongside a clinical trial in the UK (2017)
Journal Article
Carter, T., Turner, D., Sach, T., Guo, B., & Callaghan, P. (2017). Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: An economic evaluation alongside a clinical trial in the UK. BMJ Open, 7(11), e016211. https://doi.org/10.1136/bmjopen-2017-016211

© 2017 BMJ Publishing Group. All Rights Reserved. Objectives To assess the cost-effectiveness of preferred intensity exercise programme for young people with depression compared with a treatment as usual control group. Design A ‘within trial’ cost-ef... Read More about Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: An economic evaluation alongside a clinical trial in the UK.

The effects of using the PReDicT Test to guide the antidepressant treatment of depressed patients: study protocol for a randomised controlled trial (2017)
Journal Article
Kingslake, J., Dias, R., Dawson, G. R., Simon, J., Goodwin, G. M., Harmer, C. J., …Browning, M. (2017). The effects of using the PReDicT Test to guide the antidepressant treatment of depressed patients: study protocol for a randomised controlled trial. Trials, 18(1), Article 558. https://doi.org/10.1186/s13063-017-2247-2

Background Antidepressant medication is commonly used to treat depression. However, many patients do not respond to the first medication prescribed and improvements in symptoms are generally only detectable by clinicians 4–6 weeks after the medica... Read More about The effects of using the PReDicT Test to guide the antidepressant treatment of depressed patients: study protocol for a randomised controlled trial.

Monitoring oral health of people in Early Intervention for Psychosis (EIP) teams: the extended Three Shires randomised trial (2017)
Journal Article
Adams, C. E., Wells, N. C., Clifton, A., Jones, H., Simpson, J., Tosh, G., …Aggarwal, V. R. (2018). Monitoring oral health of people in Early Intervention for Psychosis (EIP) teams: the extended Three Shires randomised trial. International Journal of Nursing Studies, 77, https://doi.org/10.1016/j.ijnurstu.2017.10.005

Background: The British Society for Disability and Oral Health guidelines made recommendations for oral health care for people with mental health problems, including providing oral health advice, support, promotion and education. The effectiveness of... Read More about Monitoring oral health of people in Early Intervention for Psychosis (EIP) teams: the extended Three Shires randomised trial.

Clinical and cost-effectiveness of adapted cognitive behaviour therapy for non-cardiac chest pain: a multicentre, randomised controlled trial (2017)
Journal Article
Tyrer, P., Tyrer, H., Morriss, R., Crawford, M., Cooper, S., Yang, M., …Barrett, B. (in press). Clinical and cost-effectiveness of adapted cognitive behaviour therapy for non-cardiac chest pain: a multicentre, randomised controlled trial. Open Heart, 4(1), Article e000582. https://doi.org/10.1136/openhrt-2016-000582

Objective: To investigate the cost-effectiveness of a modified form of cognitive behaviour therapy for recurrent non-cardiac chest pain. Methods: We tested the effectiveness and cost-effectiveness of a modified form of cognitive behaviour therapy fo... Read More about Clinical and cost-effectiveness of adapted cognitive behaviour therapy for non-cardiac chest pain: a multicentre, randomised controlled trial.

Factor structure and longitudinal measurement invariance of PHQ-9 for specialist mental health care patients with persistent major depressive disorder: Exploratory Structural Equation Modelling (2017)
Journal Article
Guo, B., Kaylor-Hughes, C., Garland, A., Nixon, N., Sweeney, T., Simpson, S., …Morriss, R. (2017). Factor structure and longitudinal measurement invariance of PHQ-9 for specialist mental health care patients with persistent major depressive disorder: Exploratory Structural Equation Modelling. Journal of Affective Disorders, 219, 1-8. https://doi.org/10.1016/j.jad.2017.05.020

Background: The Patient Health Questionnaire-9 (PHQ-9) is a widely used instrument for measuring levels of depression in patients in clinical practice and academic research; its factor structure has been investigated in various samples, with limited... Read More about Factor structure and longitudinal measurement invariance of PHQ-9 for specialist mental health care patients with persistent major depressive disorder: Exploratory Structural Equation Modelling.

Feasibility of an online intervention (STAK-D) to promote physical activity in children with type 1 diabetes: protocol for a randomised controlled trial (2016)
Journal Article
Blake, H., Quirk, H., Leighton, P., Randell, T., Greening, J., Guo, B., & Glazebrook, C. (2016). Feasibility of an online intervention (STAK-D) to promote physical activity in children with type 1 diabetes: protocol for a randomised controlled trial. Trials, 17(283), https://doi.org/10.1186/s13063-016-1719-0

Background: Regular physical activity has important health benefits for children with type 1 diabetes mellitus (T1DM), yet children and their parents face barriers to participation such as lack of self-efficacy or concerns around hypoglycaemia. Multi... Read More about Feasibility of an online intervention (STAK-D) to promote physical activity in children with type 1 diabetes: protocol for a randomised controlled trial.

Supporting Kids with diabetes In Physical activity (SKIP): protocol for a randomized feasibility trial of an online intervention to promote physical activity in children with type 1 diabetes (2016)
Presentation / Conference
Blake, H., Quirk, H., Leighton, P., Randell, T., Greening, J., Knox, E., …Glazebrook, C. (2016, December). Supporting Kids with diabetes In Physical activity (SKIP): protocol for a randomized feasibility trial of an online intervention to promote physical activity in children with type 1 diabetes. Paper presented at UK Society for Behavioural Medicine 12th Annual Scientific Meeting

Cognitive behaviour therapy for long-term frequent attenders in primary care: a feasibility case series and treatment development study (2016)
Journal Article
Malins, S., Kai, J., Atha, C., Avery, A., Guo, B., James, M., …Morriss, R. K. (2016). Cognitive behaviour therapy for long-term frequent attenders in primary care: a feasibility case series and treatment development study. British Journal of General Practice, 66(651), e729-e736. https://doi.org/10.3399/bjgp16X686569

Background: Most frequent attendance in primary care is temporary. Long-term frequent attendance may be suitable for psychological intervention to address health management and service use. Aim: To explore the feasibility and acceptability of cog... Read More about Cognitive behaviour therapy for long-term frequent attenders in primary care: a feasibility case series and treatment development study.

Efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression: a randomised controlled trial (2016)
Journal Article
Morriss, R., Garland, A., Nixon, N., Guo, B., James, M., Kaylor-Hughes, C., …Dalgleish, T. (2016). Efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression: a randomised controlled trial. Lancet Psychiatry, 3(9), 821-831. https://doi.org/10.1016/s2215-0366%2816%2930143-2

Background: Persistent moderate or severe unipolar depression is common and expensive to treat. Clinical guidelines recommend combined pharmacotherapy and psychotherapy. Such treatments can take up to 1 year to show an effect, but no trials of suitab... Read More about Efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression: a randomised controlled trial.

Effectiveness and cost-effectiveness of a brief school-based group programme for parents of children at risk of ADHD: a cluster randomised controlled trial (2016)
Journal Article
Sayal, K., Taylor, J. A., Valentine, A., Guo, B., Sampson, C. J., Sellman, E., …Daley, D. (2016). Effectiveness and cost-effectiveness of a brief school-based group programme for parents of children at risk of ADHD: a cluster randomised controlled trial. Child: Care, Health and Development, 42(4), 521-533. https://doi.org/10.1111/cch.12349

Background NICE guidelines recommend a stepped care approach for the identification and management of children with, or at risk of, Attention-Deficit / Hyperactivity Disorder (ADHD). We investigated the effectiveness, cost-effectiveness and acceptab... Read More about Effectiveness and cost-effectiveness of a brief school-based group programme for parents of children at risk of ADHD: a cluster randomised controlled trial.

Protocol investigating the clinical outcomes and cost-effectiveness of cognitive–behavioural therapy delivered remotely for unscheduled care users with health anxiety: randomised controlled trial (2016)
Journal Article
Patel, S., Malins, S., Guo, B., James, M., Kai, J., Kaylor-Hughes, C., …Morriss, R. K. (2016). Protocol investigating the clinical outcomes and cost-effectiveness of cognitive–behavioural therapy delivered remotely for unscheduled care users with health anxiety: randomised controlled trial. BJPsych Open, 2, https://doi.org/10.1192/bjpo.bp.115.002220

Background Health anxiety and medically unexplained symptoms cost the National Health Service (NHS) an estimated £3 billion per year in unnecessary costs with little evidence of patient benefit. Effective treatment is rarely taken up due to issues s... Read More about Protocol investigating the clinical outcomes and cost-effectiveness of cognitive–behavioural therapy delivered remotely for unscheduled care users with health anxiety: randomised controlled trial.

Correction: Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD-'Assessing QbTest Utility in ADHD'(AQUA): A randomised controlled trial - December 01, 2014 (2016)
Journal Article
Hall, C. L., Walker, G. M. .., Valentine, A. Z., Guo, B., Kaylor-Hughes, C., James, M., …Hollis, C. (2016). Correction: Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD-'Assessing QbTest Utility in ADHD'(AQUA): A randomised controlled trial - December 01, 2014. BMJ Open, 6(1), Article e006838corr2. https://doi.org/10.1136/bmjopen-2014-006838corr2

Individual placement and support versus individual placement and support enhanced with work-focused cognitive behaviour therapy: feasibility study for a randomised controlled trial (2016)
Journal Article
Schneider, J. M., Akhtar, A., Boycott, N., Guo, B., Latimer, E., Cao, Z., & McMurran, M. (2016). Individual placement and support versus individual placement and support enhanced with work-focused cognitive behaviour therapy: feasibility study for a randomised controlled trial. British Journal of Occupational Therapy, 79(5), https://doi.org/10.1177/0308022615619184

Introduction: Employment is a key goal for many people with long-term mental health issues. Evidence-based individual placement and support is a widely advocated approach. This study explored whether individual placement and support outcomes could be... Read More about Individual placement and support versus individual placement and support enhanced with work-focused cognitive behaviour therapy: feasibility study for a randomised controlled trial.

Innovations in practice: an objective measure of attention, impulsivity and activity reduces time to confirm attention deficit/hyperactivity disorder diagnosis in children: a completed audit cycle (2016)
Journal Article
Hall, C. L., Selby, K., Guo, B., Valentine, A. Z., Walker, G. M., & Hollis, C. (2016). Innovations in practice: an objective measure of attention, impulsivity and activity reduces time to confirm attention deficit/hyperactivity disorder diagnosis in children: a completed audit cycle. Child and Adolescent Mental Health, 21(3), 175-178. https://doi.org/10.1111/camh.12140

Background Diagnosing attention deficit/hyperactivity disorder (ADHD) in children and young people typically relies on clinical observation and subjective parent, teacher and self-reports. The subjective nature of reports combined with contradicto... Read More about Innovations in practice: an objective measure of attention, impulsivity and activity reduces time to confirm attention deficit/hyperactivity disorder diagnosis in children: a completed audit cycle.

Urine tests for Down's syndrome screening (2015)
Journal Article
Alldred, S. K., Guo, B., Takwoingi, Y., Pennant, M., Wisniewski, S., Deeks, J. J., …Alldred, S. K. (2015). Urine tests for Down's syndrome screening. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD011984

Background Down's syndrome occurs when a person has three copies of chromosome 21, or the specific area of chromosome 21 implicated in causing Down's syndrome, rather than two. It is the commonest congenital cause of mental disability and also lea... Read More about Urine tests for Down's syndrome screening.

Cognitive behaviour therapy for non-cardiac pain in the chest (COPIC): a multicentre randomized controlled trial with economic evaluation (2015)
Journal Article
Tyrer, P., Tyrer, H., Cooper, S., Barrett, B., Kings, S., Lazarevic, V., …Crawford, M. (2015). Cognitive behaviour therapy for non-cardiac pain in the chest (COPIC): a multicentre randomized controlled trial with economic evaluation. BMC Psychology, 3(41), https://doi.org/10.1186/s40359-015-0099-7

Background Most patients with chest pain have nothing wrong with their cardiac function. Psychological forms of treatment for this condition are more likely to be successful than others. Methods/design A two-arm parallel controlled randomize... Read More about Cognitive behaviour therapy for non-cardiac pain in the chest (COPIC): a multicentre randomized controlled trial with economic evaluation.

Preferred intensity exercise for adolescents receiving treatment for depression: A pragmatic randomised controlled trial (2015)
Journal Article
Carter, T., Guo, B., Turner, D., Morres, I., Khalil, E., Brighton, E., …Callaghan, P. (2015). Preferred intensity exercise for adolescents receiving treatment for depression: A pragmatic randomised controlled trial. BMC Psychiatry, 15(1), Article 247. https://doi.org/10.1186/s12888-015-0638-z

© 2015 Carter et al. Background: Exercise has been shown to be effective in treating depression, but trials testing the effect of exercise for depressed adolescents utilising mental health services are rare. The aim of this study was to determine the... Read More about Preferred intensity exercise for adolescents receiving treatment for depression: A pragmatic randomised controlled trial.

Clinical characteristics of persistent frequent attenders in primary care: case–control study (2015)
Journal Article
Patel, S., Kai, J., Atha, C., Avery, A., Guo, B., James, M., …Morriss, R. (2015). Clinical characteristics of persistent frequent attenders in primary care: case–control study. Family Practice, cmv076. https://doi.org/10.1093/fampra/cmv076

Background. Most frequent attendance in primary care is temporary, but persistent frequent attendance is expensive and may be suitable for psychological intervention. To plan appropriate intervention and service delivery, there is a need for research... Read More about Clinical characteristics of persistent frequent attenders in primary care: case–control study.

Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data (2015)
Journal Article
Takwoingi, Y., Guo, B., Riley, R. D., & Deeks, J. J. (2015). Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data. Statistical Methods in Medical Research, https://doi.org/10.1177/0962280215592269

Hierarchical models such as the bivariate and hierarchical summary receiver operating characteristic (HSROC) models are recommended for meta-analysis of test accuracy studies. These models are challenging to fit when there are few studies and/or spar... Read More about Performance of methods for meta-analysis of diagnostic test accuracy with few studies or sparse data.

Correction: Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD - 'Assessing QbTest Utility in ADHD' (AQUA): A randomised controlled trial - December 01, 2014 (2015)
Journal Article
Hall, C. L., Walker, G. M., Valentine, A. Z., Guo, B., Kaylor-Hughes, C., James, M., …Hollis, C. (2015). Correction: Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD - 'Assessing QbTest Utility in ADHD' (AQUA): A randomised controlled trial - December 01, 2014. BMJ Open, 5(5), Article e006838corr1. https://doi.org/10.1136/bmjopen-2014-006838corr1

First trimester serum tests for Down's syndrome screening (2015)
Journal Article
Alldred, S. K., Takwoingi, Y., Guo, B., Pennant, M., Deeks, J. J., Neilson, J. P., & Alfirevic, Z. (2015). First trimester serum tests for Down's syndrome screening. Cochrane Database of Systematic Reviews, 11, Article CD011975. https://doi.org/10.1002/14651858.CD011975

Background Down's syndrome occurs when a person has three, rather than two copies of chromosome 21; or the specific area of chromosome 21 implicated in causing Down's syndrome. It is the commonest congenital cause of mental disability and also lea... Read More about First trimester serum tests for Down's syndrome screening.

Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD--'Assessing QbTest Utility in ADHD'(AQUA): a randomised controlled trial (2014)
Journal Article
Hall, C. L., Walker, G. M., Valentine, A. Z., Guo, B., Kaylor-Hughes, C., James, M., …Hollis, C. (2014). Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD--'Assessing QbTest Utility in ADHD'(AQUA): a randomised controlled trial. BMJ Open, 4(12), Article e006838. https://doi.org/10.1136/bmjopen-2014-006838

Introduction: The National Institute for Health and Care Excellence (NICE) guidelines for attention deficit/hyperactivity disorder (ADHD) state that young people need to have access to the best evidence-based care to improve outcome. The current ‘gol... Read More about Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD--'Assessing QbTest Utility in ADHD'(AQUA): a randomised controlled trial.

Can stroke specific vocational rehabilitation (SSVR) be delivered and measured?: feasibility RCT and economic analysis (2014)
Journal Article
Radford, K. A., Grant, M., Sinclair, E., Terry, J., Sampson, C. J., Edwards, C., …Jenkinson, M. (2014). Can stroke specific vocational rehabilitation (SSVR) be delivered and measured?: feasibility RCT and economic analysis. Clinical Rehabilitation, 28(4), https://doi.org/10.1177/0269215513506172

Background: A quarter of UK strokes occur in working age people. Fewer than half resume work. Rehabilitation frequently fails to address work needs and evidence for post-stroke vocational rehabilitation is lacking. This pilot trial tested the feas... Read More about Can stroke specific vocational rehabilitation (SSVR) be delivered and measured?: feasibility RCT and economic analysis.

Individual participant data meta-analyses should not ignore clustering (2013)
Journal Article
Abo-Zaid, G., Guo, B., Deeks, J. J., Debray, T. P., Steyerberg, E. W., Moons, K. G., & Riley, R. D. (2013). Individual participant data meta-analyses should not ignore clustering. Journal of Clinical Epidemiology, 66(8), Article 865-873.e4. https://doi.org/10.1016/j.jclinepi.2012.12.017

Objectives Individual participant data (IPD) meta-analyses often analyze their IPD as if coming from a single study. We compare this approach with analyses that rather account for clustering of patients within studies. Study Design and Setting... Read More about Individual participant data meta-analyses should not ignore clustering.

An oral health intervention for people with serious mental illness (Three Shires Early Intervention Dental Trial): study protocol for a randomised controlled trial (2013)
Journal Article
Jones, H. F., Adams, C. E., Clifton, A., Simpson, J., Tosh, G., Liddle, P. F., …Furtado, V. (2013). An oral health intervention for people with serious mental illness (Three Shires Early Intervention Dental Trial): study protocol for a randomised controlled trial. Trials, 14, Article 158. https://doi.org/10.1186/1745-6215-14-158

Background Oral health is an important part of general physical health and is essential for self-esteem, self-confidence and overall quality of life. There is a well-established link between mental illness and poor oral health. Oral health problems... Read More about An oral health intervention for people with serious mental illness (Three Shires Early Intervention Dental Trial): study protocol for a randomised controlled trial.

Second trimester serum tests for Down's Syndrome screening (2012)
Journal Article
Alldred, S. K., Deeks, J. J., Guo, B., Neilson, J. P., & Alfirevic, Z. (2012). Second trimester serum tests for Down's Syndrome screening. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD009925

Background Down's syndrome occurs when a person has three copies of chromosome 21 - or the specific area of chromosome 21 implicated in causing Down's syndrome - rather than two. It is the commonest congenital cause of mental retardation. Noninvas... Read More about Second trimester serum tests for Down's Syndrome screening.

Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK) (2011)
Journal Article
Glazebrook, C., Batty, M. J., Mullan, N., MacDonald, I., Nathan, D., Sayal, K., …Hollis, C. (2011). Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK). BMC Public Health, 11, Article 830. https://doi.org/10.1186/1471-2458-11-830

Background Low levels of physical activity in children have been linked to an increased risk of obesity, but many children lack confidence in relation to exercise (exercise self-efficacy). Factors which can impact on confidence include a chronic hea... Read More about Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK).

Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): A Study Protocol for a Randomised Controlled Trial of a Resource Kit.
Working Paper
Coleston-Shields, D. M., Challis, D., Worden, A., Broome, E., Dening, T., Guo, B., …Orrell, M. Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): A Study Protocol for a Randomised Controlled Trial of a Resource Kit

BACKGROUND Improving care at home for people with dementia is a core policy goal in the dementia strategies of many European countries. A challenge to effective home support is the occurrence of crises in the care of people with dementia which ari... Read More about Achieving Quality and Effectiveness in Dementia Using Crisis Teams (AQUEDUCT): A Study Protocol for a Randomised Controlled Trial of a Resource Kit..