Professor JANET DALY's Outputs (117)

Characterisation of three equine influenza A H3N8 viruses from Germany (2000 and 2002): Evidence for frozen evolution (2005)
Journal Article
Borchers, K., Daly, J., Stiens, G., Kreling, K., Kreling, I., & Ludwig, H. (2005). Characterisation of three equine influenza A H3N8 viruses from Germany (2000 and 2002): Evidence for frozen evolution. Veterinary Microbiology, 107(1-2), 13-21. https://doi.org/10.1016/j.vetmic.2005.01.010

Reported here are the results of antigenic and genetic characterisation of equine influenza strains causing local outbreaks reported to the Equine Diagnostic Centre in Berlin, Germany. In 2000, equine influenza virus was detected in a nasal swab from... Read More about Characterisation of three equine influenza A H3N8 viruses from Germany (2000 and 2002): Evidence for frozen evolution.

Current perspectives on control of equine influenza (2004)
Journal Article
Daly, J. M., Newton, J. R., & Mumford, J. A. (2004). Current perspectives on control of equine influenza. Veterinary Research, 35(4), 411-423. https://doi.org/10.1051/vetres%3A2004023

Influenza A viruses of the H3N8 subtype are a major cause of respiratory disease in horses. Subclinical infection with virus shedding can occur in vaccinated horses, particularly where there is a mismatch between the vaccine strains and the virus str... Read More about Current perspectives on control of equine influenza.

The effects of strain heterology on the epidemiology of equine influenza in a vaccinated population (2004)
Journal Article
Park, A., Wood, J., Daly, J., Newton, J., Glass, K., Henley, W., Mumford, J., & Grenfell, B. (2004). The effects of strain heterology on the epidemiology of equine influenza in a vaccinated population. Proceedings of the Royal Society B: Biological Sciences, 271(1548), 1547–1555. https://doi.org/10.1098/rspb.2004.2766

We assess the effects of strain heterology (strains that are immunologically similar but not identical) on equine influenza in a vaccinated population. Using data relating to individual animals, for both homologous and heterologous vaccinees, we esti... Read More about The effects of strain heterology on the epidemiology of equine influenza in a vaccinated population.

Immune responses and protective efficacy in ponies immunised with an equine influenza ISCOM vaccine containing an 'American lineage' H3N8 virus (2004)
Journal Article
Crouch, C., Daly, J., Hannant, D., Wilkins, J., & Francis, M. (2004). Immune responses and protective efficacy in ponies immunised with an equine influenza ISCOM vaccine containing an 'American lineage' H3N8 virus. Vaccine, 23(3), 418-425. https://doi.org/10.1016/j.vaccine.2004.01.074

Evidence supporting the inclusion of strains from each of the two co-circulating lineages of H3N8 equine influenza virus in vaccines (2004)
Journal Article
Daly, J. M., Yates, P. J., Newton, J. R., Park, A., Henley, W., Wood, J. L., Davis-Poynter, N., & Mumford, J. A. (2004). Evidence supporting the inclusion of strains from each of the two co-circulating lineages of H3N8 equine influenza virus in vaccines. Vaccine, 22(29-30), 4101-4109. https://doi.org/10.1016/j.vaccine.2004.02.048

Two lineages of antigenically distinct equine influenza A H3N8 subtype viruses, American and European, co-circulate. Experiments were conducted in ponies to investigate the protection induced by vaccines containing virus from one lineage against chal... Read More about Evidence supporting the inclusion of strains from each of the two co-circulating lineages of H3N8 equine influenza virus in vaccines.

Unifying the Epidemiological and Evolutionary Dynamics of Pathogens (2004)
Journal Article
Grenfell, B. T., Pybus, O. G., Gog, J. R., Wood, J. L., Daly, J. M., Mumford, J. A., & Holmes, E. C. (2004). Unifying the Epidemiological and Evolutionary Dynamics of Pathogens. Science, 303(5656), 327-332. https://doi.org/10.1126/science.1090727

A key priority for infectious disease research is to clarify how pathogen genetic variation, modulated by host immunity, transmission bottlenecks, and epidemic dynamics, determines the wide variety of pathogen phylogenies observed at scales that rang... Read More about Unifying the Epidemiological and Evolutionary Dynamics of Pathogens.

It's all in the mix: Infection transmission in populations (2003)
Journal Article
Wood, J., Newton, J., Daly, J., Park, A., & Mumford, J. (2003). It's all in the mix: Infection transmission in populations. Equine Veterinary Journal, 35(6), 526-528

Comparison of hamster and pony challenge models for evaluation of effect of antigenic drift on cross protection afforded by equine influenza vaccines (2003)
Journal Article
Daly, J., Yates, P., Browse, G., Swann, Z., Newton, J., Jessett, D., Davis-Poynter, N., & Mumford, J. (2003). Comparison of hamster and pony challenge models for evaluation of effect of antigenic drift on cross protection afforded by equine influenza vaccines. Equine Veterinary Journal, 35(5), 458-462. https://doi.org/10.2746/042516403775600433

Reasons for performing study: Vaccination and challenge studies in ponies are the most relevant experimental system for predicting whether strains included in equine influenza vaccines are relevant, but they are difficult to perform.

Objectives: I... Read More about Comparison of hamster and pony challenge models for evaluation of effect of antigenic drift on cross protection afforded by equine influenza vaccines.

Efforts to pre-empt an equine influenza epidemic (2003)
Journal Article
Mumford, J., Cardwell, J., Daly, J., & Newton, R. (2003). Efforts to pre-empt an equine influenza epidemic. Veterinary Record, 152(13), 405-406

Diagnostic methods applied to analysis of an outbreak of equine influenza in a riding school in which vaccine failure occurred (2003)
Journal Article
van Maanen, C., van Essen, G., Minke, J., Daly, J., & Yates, P. (2003). Diagnostic methods applied to analysis of an outbreak of equine influenza in a riding school in which vaccine failure occurred. Veterinary Microbiology, 93(4), 291-306. https://doi.org/10.1016/S0378-1135%2803%2900029-4

Optimising vaccination strategies in equine influenza (2003)
Journal Article
Park, A., Wood, J., Newton, J., Daly, J., Mumford, J., & Grenfell, B. (2003). Optimising vaccination strategies in equine influenza. Vaccine, 21(21-22), 2862-2870. https://doi.org/10.1016/S0264-410X%2803%2900156-7

A stochastic model of equine influenza (EI) is constructed to assess the risk of an outbreak in a Thoroughbred population at a typical flat race training yard. The model is parameterised using data from equine challenge experiments conducted by the A... Read More about Optimising vaccination strategies in equine influenza.

Plasmid DNA encoding influenza virus haemagglutinin induces Th 1 cells and protection against respiratory infection despite its limited ability to generate antibody responses (2000)
Journal Article
Johnson, P. A., Conway, M. A., Daly, J., Nicolson, C., Robertson, J., & Mills, K. H. (2000). Plasmid DNA encoding influenza virus haemagglutinin induces Th 1 cells and protection against respiratory infection despite its limited ability to generate antibody responses. Journal of General Virology, 81(7),

Direct intramuscular injection of plasmid DNA can generate immune responses against encoded antigens. However, the relative ability of DNA vaccines to induce cellular and humoral immunity after a single or booster immunization and the persistence of... Read More about Plasmid DNA encoding influenza virus haemagglutinin induces Th 1 cells and protection against respiratory infection despite its limited ability to generate antibody responses.

Vaccines against H5N1 influenza (1999)
Journal Article
Wood, J., Major, D., Daly, J., Newman, R., Dunleavy, U., Nicolson, C., Robertson, J., Schild, G., & Lee-Lin, Y. (1999). Vaccines against H5N1 influenza. Vaccine, 18(7-8), 579-580. https://doi.org/10.1016/S0264-410X%2899%2900268-6

Antigenic and genetic evolution of equine H3N8 influenza A viruses (1996)
Journal Article
Daly, J., Lai, A., Binns, M., Chambers, T., Barrandeguy, M., & Mumford, J. (1996). Antigenic and genetic evolution of equine H3N8 influenza A viruses. Journal of General Virology, 77(4), https://doi.org/10.1099/0022-1317-77-4-661

Evolution of equine influenza A H3N8 viruses was examined by antigenic and genetic analysis of a collection of isolates from around the world. It was noted that antigenic and genetic variants of equine H3N8 viruses cocirculate, and in particular that... Read More about Antigenic and genetic evolution of equine H3N8 influenza A viruses.

Genetic and antigenic analysis of the influenza virus responsible for the 1992 Hong Kong equine influenza epizootic (1994)
Journal Article
Lai, A. C., Pu Lin, Y., Powell, D. G., Shortridge, K. F., Webster, R. G., Daly, J., & Chambers, T. M. (1994). Genetic and antigenic analysis of the influenza virus responsible for the 1992 Hong Kong equine influenza epizootic. Virology, 204(2), 673-679. https://doi.org/10.1006/viro.1994.1583

An outbreak of influenza occurred among thoroughbred racehorses in Hong Kong in November-December 1992, with morbidity of 37%. All horses involved had been vaccinated against equine-1 and equine-2 influenza viruses but not against the virus responsib... Read More about Genetic and antigenic analysis of the influenza virus responsible for the 1992 Hong Kong equine influenza epizootic.

Genetic and antigenic analysis of an equine influenza H 3 isolate from the 1989 epidemic (1993)
Journal Article
Binns, M., Daly, J., Chirnside, E., Mumford, J., Wood, J., Richards, C., & Daniels, R. (1993). Genetic and antigenic analysis of an equine influenza H 3 isolate from the 1989 epidemic. Archives of Virology, 130, 33-43. https://doi.org/10.1007/BF01318994

The haemagglutinin (HA) gene from the equine influenza H3N8 isolate Suffolk/89 has been cloned by reverse transcription and polymerase chain reaction amplification. The nucleotide sequence of the HA gene was determined from two independently cloned c... Read More about Genetic and antigenic analysis of an equine influenza H 3 isolate from the 1989 epidemic.

Troubleshooting methods for the generation of novel pseudotyped viruses
Journal Article
King, B., Temperton, N., Grehan, K., Scott, S., Wright, E., Tarr, A. W., & Daly, J. M. Troubleshooting methods for the generation of novel pseudotyped viruses. Future Virology,

A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studie... Read More about Troubleshooting methods for the generation of novel pseudotyped viruses.