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The logic of the floral transition: reverse-engineering the switch controlling the identity of lateral organs (2017)
Journal Article
Dinh, J., Farcot, E., & Hodgman, C. (in press). The logic of the floral transition: reverse-engineering the switch controlling the identity of lateral organs. PLoS Computational Biology, 13(9), doi:10.1371/journal.pcbi.1005744

Much laboratory work has been carried out to determine the gene regulatory network (GRN) that results in plant cells becoming flowers instead of leaves. However, this also involves the spatial distribution of different cell types, and poses the quest... Read More about The logic of the floral transition: reverse-engineering the switch controlling the identity of lateral organs.

Genome-wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize (2017)
Journal Article
Oka, R., Zicola, J., Weber, B., Anderson, S. N., Hodgman, C., Gent, J. I., …Stam, M. (2017). Genome-wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize. Genome Biology, 18, doi:10.1186/s13059-017-1273-4

Background While most cells in multicellular organisms carry the same genetic information, in each cell type only a subset of genes is being transcribed. Such differentiation in gene expression depends, for a large part, on the activation and repr... Read More about Genome-wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize.

A methodology for elucidating regulatory mechanisms leading to changes in lipid profiles (2017)
Journal Article
Hodgman, T. C., Casbas Pinto, F., Ravipati, S., Barrett, D. A., & Hodgman, C. (2017). A methodology for elucidating regulatory mechanisms leading to changes in lipid profiles. Metabolomics, 13(7), https://doi.org/10.1007/s11306-017-1214-y

Introduction It is difficult to elucidate the metabolic and regulatory factors causing lipidome perturbations. Objectives This work simplifies this process. Methods A method has been developed to query an online holistic lipid metabolic netwo... Read More about A methodology for elucidating regulatory mechanisms leading to changes in lipid profiles.