All Outputs (2)

Oxetane Synthesis via Alcohol C–H Functionalization (2023)
Journal Article
Paul, S., Filippini, D., Ficarra, F., Melnychenko, H., Janot, C., & Silvi, M. (2023). Oxetane Synthesis via Alcohol C–H Functionalization. Journal of the American Chemical Society, 145(29), 15688–15694. https://doi.org/10.1021/jacs.3c04891

Oxetanes are strained heterocycles with unique properties that have triggered significant advances in medicinal chemistry. However, their synthesis still presents significant challenges that limit the use of this class of compounds in practical appli... Read More about Oxetane Synthesis via Alcohol C–H Functionalization.

Polarity Transduction Enables the Formal Electronically Mismatched Radical Addition to Alkenes (2023)
Journal Article
Paul, S., Filippini, D., & Silvi, M. (2023). Polarity Transduction Enables the Formal Electronically Mismatched Radical Addition to Alkenes. Journal of the American Chemical Society, 145(5), 2773-2778. https://doi.org/10.1021/jacs.2c12699

The formation of carbon-carbon bonds via the intermolecular addition of alkyl radicals to alkenes is a cornerstone of organic chemistry and plays a central role in synthesis. However, unless specific electrophilic radicals are involved, polarity matc... Read More about Polarity Transduction Enables the Formal Electronically Mismatched Radical Addition to Alkenes.