All Outputs (1571)

Uptake, safety and effectiveness of inactivated influenza vaccine in inflammatory bowel disease: a UK-wide study (2024)
Journal Article

Objective To investigate (1) the UK-wide inactivated influenza vaccine (IIV) uptake in adults with inflammatory bowel disease (IBD), (2) the association between vaccination against influenza and IBD flare and (3) the effectiveness of IIV in preventin... Read More about Uptake, safety and effectiveness of inactivated influenza vaccine in inflammatory bowel disease: a UK-wide study.

A mixed methods investigation into GP attitudes and experiences of using social prescribing in their practice (2024)
Journal Article

Aim Social prescribing (SP) enables clinicians to signpost patients to non-medical services in the community in order to support their psycho-social needs. SP has been promoted as a positive service delivery model for primary and community care; how... Read More about A mixed methods investigation into GP attitudes and experiences of using social prescribing in their practice.

Comparative cytotoxicity of Acanthamoeba castellanii-derived conditioned medium on human corneal epithelial and stromal cells (2024)
Journal Article

Soluble factors in the secretome of Acanthamoeba castellanii play crucial roles in the pathogenesis of Acanthamoeba keratitis (AK). Investigating the pathological effects of A. castellanii-derived conditioned medium (ACCM) on ocular cells can provide... Read More about Comparative cytotoxicity of Acanthamoeba castellanii-derived conditioned medium on human corneal epithelial and stromal cells.

A single-cell atlas of pig gastrulation as a resource for comparative embryology (2024)
Journal Article

Cell-fate decisions during mammalian gastrulation are poorly understood outside of rodent embryos. The embryonic disc of pig embryos mirrors humans, making them a useful proxy for studying gastrulation. Here we present a single-cell transcriptomic at... Read More about A single-cell atlas of pig gastrulation as a resource for comparative embryology.

South Georgia marine productivity over the past 15 ka and implications for glacial evolution (2024)
Journal Article

The subantarctic islands of South Georgia are located in the Southern Ocean, and they may be sensitive to future climate warming. However, due to a lack of well-dated subantarctic palaeoclimate archives, there is still uncertainty about South Georgia... Read More about South Georgia marine productivity over the past 15 ka and implications for glacial evolution.

Friction and heat partition coefficients in incremental sheet forming process (2024)
Journal Article

To understand the thermo-mechanical behaviour in incremental sheet forming (ISF), it is important to precisely determine the interfacial and thermal-relevant parameters including coefficient of friction (COF) and heat partition coefficient (HPC), and... Read More about Friction and heat partition coefficients in incremental sheet forming process.

Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire (2024)
Journal Article

Background Neuropathic-like pain, fatigue, cognitive difficulty, catastrophizing, anxiety, sleep disturbance, depression and widespread pain associate with a single factor in people with knee pain. We report the Central Aspects of Pain questionnai... Read More about Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire.

Maternity support workers’ experiences of work-place trauma and post-traumatic stress symptoms. (2024)
Journal Article

Background Maternity support workers (MSW) are now a key part of the maternity workforce. They work in environments with potential exposure to traumatic events but little is known about their rates of exposure or psychological responses. Objectiv... Read More about Maternity support workers’ experiences of work-place trauma and post-traumatic stress symptoms..

Parenting in a changing climate: the relationship between talking to children aged 5-11 about climate change, family eco-behaviours and climate change anxiety (2024)
Journal Article

Climate change has a substantial impact on human health and the increased symptoms of climate change anxiety have led to a global call for action. However, data exploring the relationship between climate change, mental health, and individuals with pa... Read More about Parenting in a changing climate: the relationship between talking to children aged 5-11 about climate change, family eco-behaviours and climate change anxiety.

Evaluation of factors predicting tinnitus outcomes following cochlear implantation: Protocol for a prospective quasi-experimental study (2024)
Journal Article

Cochlear implantation is an effective intervention to restore useful aspects of hearing function in adults with severe-to-profound hearing loss. Tinnitus, the perception of sound in the absence of an external source, is common in people with severe-t... Read More about Evaluation of factors predicting tinnitus outcomes following cochlear implantation: Protocol for a prospective quasi-experimental study.

The importance of 3D fibre architecture in cancer and implications for biomaterial model design (2024)
Journal Article

The need for improved prediction of clinical response is driving the development of cancer models with enhanced physiological relevance. A new concept of ‘precision biomaterials’ is emerging, encompassing patient-mimetic biomaterial models that seek... Read More about The importance of 3D fibre architecture in cancer and implications for biomaterial model design.

Policy Brief: Neurodiversity in the workplace (2024)
Report

Although neurodiversity is relatively common (1 in 7 people in the UK), workplaces are rarely designed with neurodiversity in mind. Neurodivergent people report additional challenges with securing and maintaining a job because the workplace environm... Read More about Policy Brief: Neurodiversity in the workplace.

MicroRNA biogenesis is broadly disrupted by inhibition of the splicing factor SF3B1 (2024)
Journal Article

In animals, microRNA (miRNA) biogenesis begins with cotranscriptional cleavage of the primary (pri-)miRNA by the Microprocessor complex. Cotranscriptional splicing has been shown to influence Microprocessor cleavage when miRNAs are hosted in introns... Read More about MicroRNA biogenesis is broadly disrupted by inhibition of the splicing factor SF3B1.

Policy Brief: Access to care for neurodiversity - ADHD and Tourette Syndrome (2024)
Report

Around 15-20% of the population is neurodivergent. Despite this, access to diagnoses and care for neurodivergent people is problematic and there is inconsistent support across the UK. Research at the University of Nottingham focuses on the impor... Read More about Policy Brief: Access to care for neurodiversity - ADHD and Tourette Syndrome.

Policy Brief: Autism and Driving (2024)
Report

More than one in 100 people in the UK are autistic. Despite the prevalence of autism within society, autistic people face barriers in their everyday lives. One example of this is with learning to drive. Research shows that autistic people are less... Read More about Policy Brief: Autism and Driving.

Valence shell electronically excited states of 1-phenylimidazole and 1-benzylimidazole (2024)
Journal Article

The valence shell electronically excited states of 1-phenylimidazole and 1-benzylimidazole have been studied by employing synchrotron radiation to measure the absolute photoabsorption cross-section of each molecule, from threshold up to an energy of... Read More about Valence shell electronically excited states of 1-phenylimidazole and 1-benzylimidazole.

Automation tools to support undertaking scoping reviews (2024)
Journal Article

Objective This paper describes several automation tools and software that can be considered during evidence synthesis projects and provides guidance for their integration in the conduct of scoping reviews. Study design and setting The guidance... Read More about Automation tools to support undertaking scoping reviews.

Uses of Linguistic Context in Speech Listening: Does Acquired Hearing Loss Lead to Reduced Engagement of Prediction? (2024)
Journal Article

Research investigating the complex interplay of cognitive mechanisms involved in speech listening for people with hearing loss has been gaining prominence. In particular, linguistic context allows the use of several cognitive mechanisms that are not... Read More about Uses of Linguistic Context in Speech Listening: Does Acquired Hearing Loss Lead to Reduced Engagement of Prediction?.

A case of renal amyloidosis associated with udder cleft dermatitis in an adult dairy cow (2024)
Journal Article

Amyloidosis is a group of disorders characterised by the injurious deposition of abnormal proteins in tissues. Most common in cattle and other animals is secondary or reactive systemic amyloidosis associated with chronic inflammation, resulting in de... Read More about A case of renal amyloidosis associated with udder cleft dermatitis in an adult dairy cow.

A Simply Accessed Approach of 2D Shaping Liquid Metal in Microwave Device Applications (2024)
Journal Article

In this letter, a simply accessed approach of 2D shaping liquid metal (LM) is presented. This approach allows a microwave device to take advantage of LM in both stretchability and removability. This approach is achieved based on the Young-Laplace the... Read More about A Simply Accessed Approach of 2D Shaping Liquid Metal in Microwave Device Applications.