All Outputs (2)

RsaL-driven negative regulation promotes heterogeneity in Pseudomonas aeruginosa quorum sensing (2023)
Journal Article
Mellini, M., Letizia, M., Caruso, L., Guiducci, A., Meneghini, C., Heeb, S., …Rampioni, G. (2023). RsaL-driven negative regulation promotes heterogeneity in Pseudomonas aeruginosa quorum sensing. mBio, 14(6), Article e02039-23. https://doi.org/10.1128/mbio.02039-23

In its canonical interpretation, quorum sensing (QS) allows single cells in a bacterial population to synchronize gene expression and hence perform specific tasks collectively once the quorum cell density is reached. However, growing evidence in diff... Read More about RsaL-driven negative regulation promotes heterogeneity in Pseudomonas aeruginosa quorum sensing.

Alkyl-quinolone-dependent quorum sensing controls prophage-mediated autolysis in Pseudomonas aeruginosa colony biofilms (2023)
Journal Article
Giallonardi, G., Letizia, M., Mellini, M., Frangipani, E., Halliday, N., Heeb, S., …Rampioni, G. (2023). Alkyl-quinolone-dependent quorum sensing controls prophage-mediated autolysis in Pseudomonas aeruginosa colony biofilms. Frontiers in Cellular and Infection Microbiology, 13, Article 1183681. https://doi.org/10.3389/fcimb.2023.1183681

Pseudomonas aeruginosa is a model quorum sensing (QS) pathogen with three interconnected QS circuits that control the production of virulence factors and antibiotic tolerant biofilms. The pqs QS system of P. aeruginosa is responsible for the biosynth... Read More about Alkyl-quinolone-dependent quorum sensing controls prophage-mediated autolysis in Pseudomonas aeruginosa colony biofilms.