Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation
(2023)
Journal Article
Goodwin, A. T., John, A. E., Joseph, C., Habgood, A., Tatler, A. L., Susztak, K., …Jenkins, R. G. (2023). Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation. Development, 150(9), https://doi.org/10.1242/dev.201046
Alveolar development and repair require tight spatiotemporal regulation of numerous signalling pathways that are influenced by chemical and mechanical stimuli. Mesenchymal cells play key roles in numerous developmental processes. Transforming growth... Read More about Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation.