All Outputs (3526)

Developing a taxonomy to describe offspring outcomes in studies involving pregnant mammals’ exposure to non-tobacco nicotine: A systematic scoping review (2023)
Journal Article
Phillips, L., Thomson, R., Coleman-Haynes, T., Cooper, S., Naughton, F., McDaid, L., Emery, J., & Coleman, T. (2023). Developing a taxonomy to describe offspring outcomes in studies involving pregnant mammals’ exposure to non-tobacco nicotine: A systematic scoping review. PLoS ONE, 18(2), Article e0280805. https://doi.org/10.1371/journal.pone.0280805

Introduction Many countries recommend Nicotine Replacement Therapy (NRT) for smoking cessation in pregnancy. Preclinical studies of nicotine exposure to pregnant mammals could indicate how nicotine may adversely affect the developing fetus. As a firs... Read More about Developing a taxonomy to describe offspring outcomes in studies involving pregnant mammals’ exposure to non-tobacco nicotine: A systematic scoping review.

Self-association of the glycopeptide antibiotic teicoplanin A2 in aqueous solution studied by molecular hydrodynamics (2023)
Journal Article
Chun, T., Pattem, J., Gillis, R. B., Dinu, V. T., Yakubov, G. E., Corfield, A. P., & Harding, S. E. (2023). Self-association of the glycopeptide antibiotic teicoplanin A2 in aqueous solution studied by molecular hydrodynamics. Scientific Reports, 13(1), Article 1969. https://doi.org/10.1038/s41598-023-28740-8

The natural glycopeptide antibiotic teicoplanin is used for the treatment of serious Gram-positive related bacterial infections and can be administered intravenously, intramuscularly, topically (ocular infections), or orally. It has also been conside... Read More about Self-association of the glycopeptide antibiotic teicoplanin A2 in aqueous solution studied by molecular hydrodynamics.

Paving the way towards future-proofing our crops (2023)
Journal Article
Baekelandt, A., Saltenis, V. L., Nacry, P., Malyska, A., Cornelissen, M., Nanda, A. K., Nair, A., Rogowsky, P., Pauwels, L., Muller, B., Collén, J., Blomme, J., Pribil, M., Scharff, L. B., Davies, J., Wilhelm, R., Rolland, N., Harbinson, J., Boerjan, W., Murchie, E. H., …Parry, M. A. (2023). Paving the way towards future-proofing our crops. Food and Energy Security, 12(3), Article e441. https://doi.org/10.1002/fes3.441

To meet the increasing global demand for food, feed, fibre and other plant-derived products, a steep increase in crop productivity is a scientifically and technically challenging imperative. The CropBooster-P project, a response to the H2020 call ‘Fu... Read More about Paving the way towards future-proofing our crops.

Plasma Sphingoid Base Profiles of Patients Diagnosed with Intrinsic or Idiosyncratic Drug-induced Liver Injury (2023)
Journal Article
Gai, Z., Samodelov, S. L., Alecu, I., Hornemann, T., Grove, J. I., Aithal, G. P., Visentin, M., & Kullak-Ublick, G. A. (2023). Plasma Sphingoid Base Profiles of Patients Diagnosed with Intrinsic or Idiosyncratic Drug-induced Liver Injury. International Journal of Molecular Sciences, 24(3), Article 3013. https://doi.org/10.3390/ijms24033013

Sphingolipids are exceptionally diverse, comprising hundreds of unique species. The bulk of circulating sphingolipids are synthesized in the liver, thereby plasma sphingolipid profiles represent reliable surrogates of hepatic sphingolipid metabolism... Read More about Plasma Sphingoid Base Profiles of Patients Diagnosed with Intrinsic or Idiosyncratic Drug-induced Liver Injury.

The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials (2023)
Journal Article
Barker, T. H., Stone, J. C., Sears, K., Klugar, M., Tufanaru, C., Leonardi-Bee, J., Aromataris, E., & Munn, Z. (2023). The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials. JBI Evidence Synthesis, 21(3), 494-506. https://doi.org/10.11124/JBIES-22-00430

JBI recently began the process of updating and revising its suite of critical appraisal tools to ensure that these tools remain compatible with recent developments within risk of bias science. Following a rigorous development process led by the JBI E... Read More about The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials.

The Effects of Economic Policy Instruments of Diffuse Water Pollution from Agriculture: A Comparative Analysis of China and the UK (2023)
Journal Article
Zou, J., Chen, X., Liu, F., Wang, F., Wu, B., & Yang, N. (2023). The Effects of Economic Policy Instruments of Diffuse Water Pollution from Agriculture: A Comparative Analysis of China and the UK. Water, 15(4), Article 637. https://doi.org/10.3390/w15040637

The world is facing the challenge of increasing grain production and improving the environment, in which the treatment of diffuse water pollution from agriculture (DWP) is the important content. Traditional administrative means are still unable to so... Read More about The Effects of Economic Policy Instruments of Diffuse Water Pollution from Agriculture: A Comparative Analysis of China and the UK.

Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML (2023)
Journal Article
James, J. R., Curd, J., Ashworth, J. C., Abuhantash, M., Grundy, M., Seedhouse, C. H., Arkill, K. P., Wright, A. J., Merry, C. L. R., & Thompson, A. (2023). Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML. International Journal of Molecular Sciences, 24(4), Article 4235. https://doi.org/10.3390/ijms24044235

In vivo models of acute myeloid leukemia (AML) are low throughput, and standard liquid culture models fail to recapitulate the mechanical and biochemical properties of the extracellular matrix-rich protective bone marrow niche that contributes to dru... Read More about Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML.

Integration of Blockchain and Digital Twins in the Smart Built Environment Adopting Disruptive Technologies—A Systematic Review (2023)
Journal Article
Sadri, H., Yitmen, I., Tagliabue, L. C., Westphal, F., Tezel, A., Taheri, A., & Sibenik, G. (2023). Integration of Blockchain and Digital Twins in the Smart Built Environment Adopting Disruptive Technologies—A Systematic Review. Sustainability, 15(4), Article 3713. https://doi.org/10.3390/su15043713

The integration of blockchain and digital twins (DT) for better building-lifecycle data management has recently received much attention from researchers in the field. In this respect, the adoption of enabling technologies such as artificial intellige... Read More about Integration of Blockchain and Digital Twins in the Smart Built Environment Adopting Disruptive Technologies—A Systematic Review.

Parity violation in the scalar trispectrum: no-go theorems and yes-go examples (2023)
Journal Article
Cabass, G., Jazayeri, S., Pajer, E., & Stefanyszyn, D. (2023). Parity violation in the scalar trispectrum: no-go theorems and yes-go examples. Journal of High Energy Physics, 2023(2), Article 21. https://doi.org/10.1007/jhep02%282023%29021

We derive a set of no-go theorems and yes-go examples for the parity-odd primordial trispectrum of curvature perturbations. We work at tree-level in the decoupling limit of the Effective Field Theory of Inflation and assume scale invariance and a Bun... Read More about Parity violation in the scalar trispectrum: no-go theorems and yes-go examples.

The impact of psyllium gelation behaviour on in vitro colonic fermentation properties (2023)
Journal Article
Harris, H. C., Pereira, N., Koev, T., Khimyak, Y. Z., Yakubov, G. E., & Warren, F. J. (2023). The impact of psyllium gelation behaviour on in vitro colonic fermentation properties. Food Hydrocolloids, 139, Article 108543. https://doi.org/10.1016/j.foodhyd.2023.108543

Psyllium is a viscous, gel forming fibre with properties that have led it to be used for alleviating gastrointestinal discomfort. We have used previously identified fractions of psyllium with differing flow properties. Fraction 1 (F1) forms a non-gel... Read More about The impact of psyllium gelation behaviour on in vitro colonic fermentation properties.

eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation (2023)
Journal Article
Schmidt, T., Dabrowska, A., Waldron, J. A., Hodge, K., Koulouras, G., Gabrielsen, M., Munro, J., Tack, D. C., Harris, G., McGhee, E., Scott, D., Carlin, L., Huang, D., Le Quesne, J., Zanivan, S., Wilczynska, A., & Bushell, M. (2023). eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation. Nucleic Acids Research, 51(4), 1859-1879. https://doi.org/10.1093/nar/gkad030

Altered eIF4A1 activity promotes translation of highly structured, eIF4A1-dependent oncogene mRNAs at root of oncogenic translational programmes. It remains unclear how these mRNAs recruit and activate eIF4A1 unwinding specifically to facilitate thei... Read More about eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation.

Fission, Self-Interest and Commonsense Ethics (2023)
Journal Article
Noonan, H. (2023). Fission, Self-Interest and Commonsense Ethics. Philosophia, https://doi.org/10.1007/s11406-023-00611-6

Jacob Ross argues that the fission cases discussed in the personal identity literature cannot be accommodated without rejecting basic intuitions of everyday ethical thinking. He notes that many philosophers have responded to the challenge of fission... Read More about Fission, Self-Interest and Commonsense Ethics.

Editorial: Lianas, ecosystems, and global change (2023)
Journal Article
van der Heijden, G. M., Schnitzer, S. A., & Meunier, F. (2023). Editorial: Lianas, ecosystems, and global change. Frontiers in Forests and Global Change, 6, Article 1079620. https://doi.org/10.3389/ffgc.2023.1079620

Lianas (woody vines) are an abundant and diverse plant group in tropical ecosystems (Gentry, 1991; Dewalt et al., 2014). While they enhance forest canopy connectivity and provide food and shelter for tropical fauna (Yanoviak and Schnitzer, 2013; Schn... Read More about Editorial: Lianas, ecosystems, and global change.

Long-distance hormone transport via the phloem (2023)
Journal Article
Collis, H. L., Owen, M. R., & Band, L. R. (2023). Long-distance hormone transport via the phloem. Journal of Theoretical Biology, 562, Article 111415. https://doi.org/10.1016/j.jtbi.2023.111415

Several key plant hormones are synthesised in the shoot and are advected within the phloem to the root tip. In the root tip, these hormones regulate growth and developmental processes, and responses to environmental cues. However, we lack understandi... Read More about Long-distance hormone transport via the phloem.

Prevalence and risk factors for tobacco, khat and alcohol consumption among high school students in Ethiopia (2023)
Journal Article
Hirpa, S., Fogarty, A. W., Addissie, A., Bauld, L., Frese, T., Unverzagt, S., Kantelhardt, E. J., Getachew, S., & Deressa, W. (2023). Prevalence and risk factors for tobacco, khat and alcohol consumption among high school students in Ethiopia. BMC Public Health, 23, Article 226. https://doi.org/10.1186/s12889-023-15088-x

Background:
Tobacco, khat, alcohol and marijuana are the main risk factors for non-communicable diseases. There are limited studies on substance use in Ethiopia, especially among secondary school students. This study aims to determine the epidemiol... Read More about Prevalence and risk factors for tobacco, khat and alcohol consumption among high school students in Ethiopia.

The Role of Community Organisations in the Collective Mobilisation of Migrant Workers: The Importance of a ‘Community’-Oriented Perspective (2023)
Journal Article
Jiang, J., & Korczynski, M. (2024). The Role of Community Organisations in the Collective Mobilisation of Migrant Workers: The Importance of a ‘Community’-Oriented Perspective. Work, Employment and Society, 38(2), 339-357. https://doi.org/10.1177/09500170221138008

In examining the collective mobilisation of migrant workers, scholars have explored the emergence of community organisations as alternative forms of worker representation. However, community unionism scholars tend to adopt a union-centric perspective... Read More about The Role of Community Organisations in the Collective Mobilisation of Migrant Workers: The Importance of a ‘Community’-Oriented Perspective.

Place-Names, People, and Landscape in Medieval Staffordshire (2023)
Book Chapter
Baker, J., Carroll, J., & Kilby, S. (2023). Place-Names, People, and Landscape in Medieval Staffordshire. In I. Atherton, M. Blake, A. Sargent, & A. Tomkins (Eds.), Local Histories: Essays in Honour of Nigel Tringham (115-131). Staffordshire Record Society

Exploring Pharmacological Treatments for Chronic Idiopathic Constipation in Adults: A Look Back to the Future (2023)
Journal Article
Bassotti, G., Villanacci, V., & Corsetti, M. (2023). Exploring Pharmacological Treatments for Chronic Idiopathic Constipation in Adults: A Look Back to the Future. Journal of Clinical Medicine, 12(4), Article 1702. https://doi.org/10.3390/jcm12041702

Despite great progress in pharmaceutical research, the medical treatment of chronic idiopathic constipation is far from ideal. The aim of the present article was to review literature data, focusing on poorly studied or commercially unavailable/unappr... Read More about Exploring Pharmacological Treatments for Chronic Idiopathic Constipation in Adults: A Look Back to the Future.

Using (1+1)D quantum cellular automata for exploring collective effects in large-scale quantum neural networks (2023)
Journal Article
Gillman, E., Carollo, F., & Lesanovsky, I. (2023). Using (1+1)D quantum cellular automata for exploring collective effects in large-scale quantum neural networks. Physical Review E, 107(2), Article L022102. https://doi.org/10.1103/PhysRevE.107.L022102

Central to the field of quantum machine learning is the design of quantum perceptrons and neural network architectures. A key question in this regard is the impact of quantum effects on the way such models process information. Here, we establish a co... Read More about Using (1+1)D quantum cellular automata for exploring collective effects in large-scale quantum neural networks.

Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial. (2023)
Journal Article
Horne, A. W., Tong, S., Moakes, C. A., Middleton, L. J., Duncan, W. C., Mol, B. W., Whitaker, L. H., Jurkovic, D., Coomarasamy, A., Nunes, N., Holland, T., Clarke, F., Doust, A. M., & Daniels, J. P. (2023). Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet, 401(10377), 655-663. https://doi.org/10.1016/S0140-6736%2822%2902478-3

Background

Tubal ectopic pregnancies can cause substantial morbidity or even death. Current treatment is with methotrexate or surgery. Methotrexate treatment fails in approximately 30% of women who subsequently require rescue surgery. Gefitinib, a... Read More about Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial..