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Reinforcing fibres (2023)
Book Chapter
Parsons, A. (2023). Reinforcing fibres. In L. Harper, & M. Clifford (Eds.), Design and Manufacture of Structural Composites (19-34). Elsevier. https://doi.org/10.1016/B978-0-12-819160-6.00008-1

This chapter provides information on the type of reinforcing fibres commonly used in polymer composites. Inorganic and organic fibres are described along with general information on their manufacture, applications, and representative properties. Suit... Read More about Reinforcing fibres.

Performance and application of Si/ Ti3C2Tx (MXene) composites in lithium ion battery (2023)
Journal Article
Jiang, T., Xiong, Q., Yang, H., & Chen, G. Z. (2023). Performance and application of Si/ Ti3C2Tx (MXene) composites in lithium ion battery. JPhys Energy, 5(1), Article 014020. https://doi.org/10.1088/2515-7655/acb6b4

The excellent theoretical specific charge (lithium) storage capacity and rich abundance of silicon (Si), and the good mechanical and electrical properties of titanium based MXene (Ti3C2Tx) nanosheets promise high performance composites (Si/Ti3C2Tx) f... Read More about Performance and application of Si/ Ti3C2Tx (MXene) composites in lithium ion battery.

A primer to directed evolution: current methodologies and future directions (2023)
Journal Article
Sellés Vidal, L., Isalan, M., Heap, J. T., & Ledesma-Amaro, R. (2023). A primer to directed evolution: current methodologies and future directions. RSC Chemical Biology, 2023(4), 271-291. https://doi.org/10.1039/d2cb00231k

Directed evolution is one of the most powerful tools for protein engineering and functions by harnessing natural evolution, but on a shorter timescale. It enables the rapid selection of variants of biomolecules with properties that make them more sui... Read More about A primer to directed evolution: current methodologies and future directions.

Higher-spin self-dual Yang-Mills and gravity from the twistor space (2023)
Journal Article
Herfray, Y., Krasnov, K., & Skvortsov, E. (2023). Higher-spin self-dual Yang-Mills and gravity from the twistor space. Journal of High Energy Physics, 2023, Article 158. https://doi.org/10.1007/jhep01%282023%29158

We lift the recently proposed theories of higher-spin self-dual Yang-Mills (SDYM) and gravity (SDGR) to the twistor space. We find that the most natural room for their twistor formulation is not in the projective, but in the full twistor space, which... Read More about Higher-spin self-dual Yang-Mills and gravity from the twistor space.

Hippocampal resection in temporal lobe epilepsy: Do we need to resect the tail? (2023)
Journal Article
Dasgupta, D., Finn, R., Chari, A., Giampiccolo, D., de Tisi, J., O’Keeffe, A. G., …Duncan, J. S. (2023). Hippocampal resection in temporal lobe epilepsy: Do we need to resect the tail?. Epilepsy Research, 190, Article 107086. https://doi.org/10.1016/j.eplepsyres.2023.107086

Introduction: Anteromesial temporal lobe resection is the most common surgical technique used to treat drug-resistant mesial temporal lobe epilepsy, particularly when secondary to hippocampal sclerosis. Structural and functional imaging data suggest... Read More about Hippocampal resection in temporal lobe epilepsy: Do we need to resect the tail?.

Rationale and Design of a randomized double-blind 2 × 2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute mild ischemic stroke or high-risk TIA with intracranial or extracranial atherosclerosis (INSPIRES) (2023)
Journal Article
Gao, Y., Pan, Y., Han, S., Chen, W., Jing, J., Wang, C., …Wang, Y. (2023). Rationale and Design of a randomized double-blind 2 × 2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute mild ischemic stroke or high-risk TIA with intracranial or extracranial atherosclerosis (INSPIRES). Stroke and Vascular Neurology, 8(3), Article e002084. https://doi.org/10.1136/svn-2022-002084

Background: It remains unclear if intensive antiplatelet and statin treatments begun within 24–72 hours of cerebral ischaemic events from intracranial or extracranial atherosclerosis is effective or safe.
Methods: The Intensive Statin and Antiplatel... Read More about Rationale and Design of a randomized double-blind 2 × 2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute mild ischemic stroke or high-risk TIA with intracranial or extracranial atherosclerosis (INSPIRES).

Real-Time Monitoring of Bubbles and Crashes (2023)
Journal Article
Whitehouse, E. J., Harvey, D. I., & Leybourne, S. J. (2023). Real-Time Monitoring of Bubbles and Crashes. Oxford Bulletin of Economics and Statistics, 85(3), 482-513. https://doi.org/10.1111/obes.12540

Given the financial and economic damage that can be caused by the collapse of an asset price bubble, it is of critical importance to rapidly detect the onset of a crash once a bubble has been identified. We develop a real-time monitoring procedure fo... Read More about Real-Time Monitoring of Bubbles and Crashes.

Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack (2023)
Journal Article
Krishnan, K., Nguyen, T. N., Appleton, J. P., Law, Z. K., Caulfied, M., Cabrera, C. P., …Bath, P. M. (2023). Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack. Stroke: Vascular and Interventional Neurology, 3(3), Article e000576. https://doi.org/10.1161/svin.122.000576

Acute ischemic stroke is a leading cause of death and major disability worldwide. Approximately 50% of ischemic strokes are caused by atherothrombotic occlusion of the cerebral arteries, and antiplatelets are the mainstay of secondary stroke preventa... Read More about Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack.

OptoRheo: Simultaneous in situ micro-mechanical sensing and 3D imaging of live cell cultures (2023)
Preprint / Working Paper
Mendonca, T., Lis-Slimak, K., Matheson, A. B., Smith, M. G., Anane-Adjei, A. B., Cavanagh, R., …Wright, A. J. OptoRheo: Simultaneous in situ micro-mechanical sensing and 3D imaging of live cell cultures

Biomechanical cues from the extracellular matrix (ECM) are essential for directing many cellular processes, from normal development and repair, to disease progression. To better understand cell-matrix interactions, we have developed a new instrument... Read More about OptoRheo: Simultaneous in situ micro-mechanical sensing and 3D imaging of live cell cultures.

Working at Home: Architects during the pandemic in China (2023)
Book Chapter
Xu, Y., Borsi, K., & Hale, J. (2023). Working at Home: Architects during the pandemic in China. In P. Sparke, E. Ioannidou, P. Kirkham, S. Knott, & J. Scholze (Eds.), Interiors in the Era of Covid-19: Interior Design between the Public and Private Realms (101-111). Bloomsbury Publishing

Thrombectomy-Capable Stroke Centre—A Key to Acute Stroke Care System Improvement? Retrospective Analysis of Safety and Efficacy of Endovascular Treatment in Cardiac Cathlab (2023)
Journal Article
Pawłowski, K., Dziadkiewicz, A., Podlasek, A., Klaudel, J., Mączkowiak, A., & Szołkiewicz, M. (2023). Thrombectomy-Capable Stroke Centre—A Key to Acute Stroke Care System Improvement? Retrospective Analysis of Safety and Efficacy of Endovascular Treatment in Cardiac Cathlab. International Journal of Environmental Research and Public Health, 20(3), Article 2232. https://doi.org/10.3390/ijerph20032232

The optimal structure of the acute ischaemic stroke treatment network is unknown and eagerly sought. To make it most effective, different treatment and transportation strategies have been developed and investigated worldwide. Since only a fraction of... Read More about Thrombectomy-Capable Stroke Centre—A Key to Acute Stroke Care System Improvement? Retrospective Analysis of Safety and Efficacy of Endovascular Treatment in Cardiac Cathlab.

Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites (2023)
Journal Article
Fry, A., White, B., Nagarwalla, D., Shelton, J., & Jack, R. H. (2023). Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites. BMJ Open, 13(1), Article e062079. https://doi.org/10.1136/bmjopen-2022-062079

Objectives: Cancer stage at diagnosis is a determinant of treatment options and survival. Previous research has shown differences in barriers to presentation with cancer between ethnic groups. The completeness and quality of cancer stage and ethnicit... Read More about Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites.

Inhibition of Intimal Thickening By PRH (Proline-Rich Homeodomain) in Mice (2023)
Journal Article
Reolizo, L. M., Williams, H., Wadey, K., Frankow, A., Li, Z., Gaston, K., …George, S. J. (2023). Inhibition of Intimal Thickening By PRH (Proline-Rich Homeodomain) in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 43(3), 456-473. https://doi.org/10.1161/ATVBAHA.122.318367

Background: Late vein graft failure is caused by intimal thickening resulting from endothelial cell (EC) damage and inflammation which promotes vascular smooth muscle cell (VSMC) dedifferentiation, migration, and proliferation. Nonphosphorylatable PR... Read More about Inhibition of Intimal Thickening By PRH (Proline-Rich Homeodomain) in Mice.

Clinical academics' experiences during the COVID-19 pandemic: a qualitative study of challenges and opportunities when working at the clinical frontline (2023)
Journal Article
Trusson, D., Rowley, E., & Bramley, L. (2023). Clinical academics' experiences during the COVID-19 pandemic: a qualitative study of challenges and opportunities when working at the clinical frontline. BMJ Leader, 7(4), 266-272. https://doi.org/10.1136/leader-2020-000414

Objectives: This study explored the experiences of clinical academics during the COVID-19 pandemic. The aim was to identify challenges and benefits associated with returning to, or increasing hours at, the clinical frontline. Design: Qualitative data... Read More about Clinical academics' experiences during the COVID-19 pandemic: a qualitative study of challenges and opportunities when working at the clinical frontline.

Loss of muscle mass in the immediate post-operative period is associated with inadequate dietary protein and energy intake (2023)
Journal Article
Hardy, E. J., Deane, C. S., Lund, J. N., & Phillips, B. E. (2023). Loss of muscle mass in the immediate post-operative period is associated with inadequate dietary protein and energy intake. European Journal of Clinical Nutrition, 77, 503-505. https://doi.org/10.1038/s41430-023-01264-0

Despite the implementation of ‘Enhanced Recovery After Surgery’ (ERAS) protocols, major abdominal surgery is still associated with significant and detrimental losses of muscle mass and function in the post-operative period. Although ERAS protocols ad... Read More about Loss of muscle mass in the immediate post-operative period is associated with inadequate dietary protein and energy intake.

How to Conduct International Geriatric Rehabilitation Research? (2023)
Journal Article
Haaksma, M. L., Gordon, A. L., van Dam van Isselt, E. F., Schols, J. M., Everink, I. H., Cameron, I. D., …Achterberg, W. P. (2023). How to Conduct International Geriatric Rehabilitation Research?. Journal of Clinical Medicine, 12(3), Article 951. https://doi.org/10.3390/jcm12030951

With an ageing global population and an increasing focus on aging in place, the number of people in need of geriatric rehabilitation (GR) is rapidly increasing. As current GR practice is very heterogenous, cross-country comparisons could allow us to... Read More about How to Conduct International Geriatric Rehabilitation Research?.

Inferring the basis of binaural detection with a modified autoencoder (2023)
Journal Article
Smith, S., Sollini, J., & Akeroyd, M. A. (2023). Inferring the basis of binaural detection with a modified autoencoder. Frontiers in Neuroscience, 17, Article 1000079. https://doi.org/10.3389/fnins.2023.1000079

The binaural system utilizes interaural timing cues to improve the detection of auditory signals presented in noise. In humans, the binaural mechanisms underlying this phenomenon cannot be directly measured and hence remain contentious. As an alterna... Read More about Inferring the basis of binaural detection with a modified autoencoder.

C-terminal citrullinated peptide alters antigen-specific APC:T cell interactions leading to breach of immune tolerance (2023)
Journal Article
Malcolm, J., Nyirenda, M. H., Brown, J. L., Adrados-Planell, A., Campbell, L., Butcher, J. P., …Culshaw, S. (2023). C-terminal citrullinated peptide alters antigen-specific APC:T cell interactions leading to breach of immune tolerance. Journal of Autoimmunity, 135, Article 102994. https://doi.org/10.1016/j.jaut.2023.102994

In rheumatoid arthritis, the emergence of anti-citrullinated autoimmunity is associated with HLA-antigen-T cell receptor complexes. The precise mechanisms underpinning this breach of tolerance are not well understood. Porphyromonas gingivalis express... Read More about C-terminal citrullinated peptide alters antigen-specific APC:T cell interactions leading to breach of immune tolerance.