All Outputs (2)

Structure of the human Ccr4-Not nuclease module using X-ray crystallography and electron paramagnetic resonance spectroscopy distance measurements (2021)
Journal Article
Zhang, Q., Pavanello, L., Potapov, A., Bartlam, M., & Winkler, G. S. (2022). Structure of the human Ccr4-Not nuclease module using X-ray crystallography and electron paramagnetic resonance spectroscopy distance measurements. Protein Science, 31(3), 758-764. https://doi.org/10.1002/pro.4262

Regulated degradation of mature, cytoplasmic mRNA is a key step in eukaryotic gene regulation. This process is typically initiated by the recruitment of deadenylase enzymes by cis-acting elements in the 3' untranslated region resulting in the shorten... Read More about Structure of the human Ccr4-Not nuclease module using X-ray crystallography and electron paramagnetic resonance spectroscopy distance measurements.

Application of DNP-enhanced solid-state NMR to studies of amyloid-? peptide interaction with lipid membranes (2021)
Journal Article
Deo, T., Cheng, Q., Paul, S., Qiang, W., & Potapov, A. (2021). Application of DNP-enhanced solid-state NMR to studies of amyloid-? peptide interaction with lipid membranes. Chemistry and Physics of Lipids, 236, Article 105071. https://doi.org/10.1016/j.chemphyslip.2021.105071

The cellular membrane disruption induced by the aggregation of Aβ peptide has been proposed as a plausible cause of neuronal cell death during Alzheimer’s disease. The molecular-level details of the Aβ interaction with cellular membranes were previou... Read More about Application of DNP-enhanced solid-state NMR to studies of amyloid-? peptide interaction with lipid membranes.