All Outputs (2)

Reliable computational quantification of liver fibrosis is compromised by inherent staining variation (2021)
Journal Article
Astbury, S., Grove, J. I., Dorward, D. A., Guha, I. N., Fallowfield, J. A., & Kendall, T. J. (2021). Reliable computational quantification of liver fibrosis is compromised by inherent staining variation. Journal of Pathology: Clinical Research, 7(5), 471-481. https://doi.org/10.1002/cjp2.227

Biopsy remains the gold standard measure for staging liver disease, both to inform prognosis and to assess the response to a given treatment. Semiquantitative scores such as the Ishak fibrosis score are used for evaluation. These scores are utilised... Read More about Reliable computational quantification of liver fibrosis is compromised by inherent staining variation.

Pain severity correlates with biopsy mediated colonic afferent activation but not psychological scores in IBS-D patients (2021)
Journal Article
Cibert-Goton, V., Lam, C., Lingaya, M., Falcone, Y., Wood, J. N., Bulmer, D. C., & Spiller, R. (2021). Pain severity correlates with biopsy mediated colonic afferent activation but not psychological scores in IBS-D patients. Clinical and Translational Gastroenterology, 12(2), Article e00313. https://doi.org/10.14309/ctg.0000000000000313

Objectives: Despite heterogeneity an increased prevalence of psychological co-morbidity and an altered pro-nociceptive gut microenvironment have repeatedly emerged as causative pathophysiology in patients with irritable bowel syndrome(IBS). Our aim w... Read More about Pain severity correlates with biopsy mediated colonic afferent activation but not psychological scores in IBS-D patients.