All Outputs (11)

Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease (2021)
Journal Article
Shariff, S., Moran, G., Grimes, C., & Cooney, R. M. (2021). Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease. Nutrients, 13(12), Article 4389. https://doi.org/10.3390/nu13124389

Despite the increasing array of medications available for the treatment of Crohn’s disease and a focus on mucosal healing, approximately 35% of patients with Crohn’s disease undergo bowel surgery at some stage. The importance of nutritional optimisat... Read More about Current Use of EEN in Pre-Operative Optimisation in Crohn’s Disease.

Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study (2021)
Journal Article
Alyami, A., Hoad, C. L., Tench, C., Bannur, U., Clarke, C., Latief, K., …Moran, G. W. (2021). Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study. Diagnostics, 11(11), Article 2135. https://doi.org/10.3390/diagnostics11112135

Perianal Crohn’s Disease (pCD) is a common manifestation of Crohn’s Disease. Absence of reliable disease measures makes disease monitoring unreliable. Qualitative MRI has been increasingly used for diagnosing and monitoring pCD and has shown potentia... Read More about Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study.

Diagnostic Accuracy of Non-Invasive Imaging for Detection of Colonic Inflammation in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis (2021)
Journal Article
Alshammari, M. T., Stevenson, R., Abdul-Aema, B., Zou, G., Jairath, V., Radford, S., …Moran, G. W. (2021). Diagnostic Accuracy of Non-Invasive Imaging for Detection of Colonic Inflammation in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. Diagnostics, 11(10), Article 1926. https://doi.org/10.3390/diagnostics11101926

Endoscopy is the gold standard for objective assessment of colonic disease activity in inflammatory bowel disease (IBD). Non-invasive colonic imaging using bowel ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) may have... Read More about Diagnostic Accuracy of Non-Invasive Imaging for Detection of Colonic Inflammation in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

Review article: The aetiology of fatigue in inflammatory bowel disease and potential therapeutic management strategies (2021)
Journal Article
McGing, J. J., Radford, S. J., Francis, S. T., Serres, S., Greenhaff, P. L., & Moran, G. W. (2021). Review article: The aetiology of fatigue in inflammatory bowel disease and potential therapeutic management strategies. Alimentary Pharmacology and Therapeutics, 54(4), 368-387. https://doi.org/10.1111/apt.16465

Background: Fatigue is the inability to achieve or maintain an expected work output resulting from central or peripheral mechanisms. The prevalence of inflammatory bowel disease (IBD) fatigue can reach 86% in active disease, persisting in 50%-52% of... Read More about Review article: The aetiology of fatigue in inflammatory bowel disease and potential therapeutic management strategies.

Clinical Utility of small bowel ultrasound assessment of Crohn’s Disease in Adults: A systematic scoping review (2021)
Journal Article
Radford, S. J., Clarke, C. G., Shinkins, B., Leighton, P., Taylor, S. A., & Moran, G. W. (2022). Clinical Utility of small bowel ultrasound assessment of Crohn’s Disease in Adults: A systematic scoping review. Frontline Gastroenterology, 13(4), 280-286. https://doi.org/10.1136/flgastro-2021-101897

Background: Ultrasound is an alternative to Magnetic Resonance Enterography, and has the potential to significantly reduce waiting times, expedite clinical decision making and improve patient experience. Point of care ultrasound is an advantage of th... Read More about Clinical Utility of small bowel ultrasound assessment of Crohn’s Disease in Adults: A systematic scoping review.

Test–retest assessment of non-contrast MRI sequences to characterise and quantify the small bowel wall in healthy participants (2021)
Journal Article
Alyami, A. S., Williams, H. G., Argyriou, K., Gunn, D., Wilkinson-Smith, V., White, J. R., …Hoad, C. L. (2021). Test–retest assessment of non-contrast MRI sequences to characterise and quantify the small bowel wall in healthy participants. Magnetic Resonance Materials in Physics, Biology and Medicine, 34, 791-804. https://doi.org/10.1007/s10334-021-00931-2

Objective: Quantitative Magnetic Resonance Imaging sequences have been investigated as objective imaging biomarkers of fibrosis and inflammation in Crohn’s disease. Aim: To determine the repeatability and inter- and intra-observer agreement of these... Read More about Test–retest assessment of non-contrast MRI sequences to characterise and quantify the small bowel wall in healthy participants.

Letter: risk of severe COVID-19 outcomes associated with inflammatory bowel disease medications - reassuring insights from the United Kingdom PREPARE-IBD multicentre cohort study (2021)
Journal Article
Lamb, C. A., Sebastian, S., Kent, A. J., Segal, J. P., Gonzalez, H. A., Brookes, M. J., …Kennedy, N. A. (2021). Letter: risk of severe COVID-19 outcomes associated with inflammatory bowel disease medications - reassuring insights from the United Kingdom PREPARE-IBD multicentre cohort study. Alimentary Pharmacology and Therapeutics, 53(11), 1236-1240. https://doi.org/10.1111/apt.16349

Inflammatory bowel disease clinical service recovery during the COVID-19 pandemic (2021)
Journal Article
Din, S., Gaya, D., Kammermeier, J., Lamb, C. A., Macdonald, J., Moran, G., …Arnott, I. D. (2022). Inflammatory bowel disease clinical service recovery during the COVID-19 pandemic. Frontline Gastroenterology, 13(1), 77-81. https://doi.org/10.1136/flgastro-2021-101805

The Gut–Brain Axis and Its Role in Controlling Eating Behavior in Intestinal Inflammation (2021)
Journal Article
Moran, G. W., & Thapaliya, G. (2021). The Gut–Brain Axis and Its Role in Controlling Eating Behavior in Intestinal Inflammation. Nutrients, 13(3), Article 981. https://doi.org/10.3390/nu13030981

Malnutrition represents a major problem in the clinical management of the inflammatory bowel disease (IBD). Presently, our understanding of the cross-link between eating behavior and intestinal inflammation is still in its infancy. Crohn’s disease... Read More about The Gut–Brain Axis and Its Role in Controlling Eating Behavior in Intestinal Inflammation.

Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study (2021)
Journal Article
Sebastian, S., Walker, G. J., Kennedy, N. A., Conley, T. E., Patel, K. V., Subramanian, S., …Zafar, M. (2021). Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study. Lancet Gastroenterology and Hepatology, 6(4), 271-281. https://doi.org/10.1016/s2468-1253%2821%2900016-9

Background There is a paucity of evidence to support safe and effective management of patients with acute severe ulcerative colitis during the COVID-19 pandemic. We sought to identify alterations to established conventional evidence-based management... Read More about Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study.

SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement (2021)
Journal Article
Alexander, J. L., Moran, G., Gaya, D. R., Raine, T., Hart, A., Kennedy, N. A., …Powell, N. (2021). SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement. Lancet Gastroenterology and Hepatology, 6(3), 218-224. https://doi.org/10.1016/S2468-1253%2821%2900024-8

SARS-CoV2 has caused a global health crisis and mass vaccination programmes provide the best opportunity for controlling transmission and protecting populations. Despite the impressive clinical trial results of the BNT162b2 (Pfizer/BioNTech), ChAdOx1... Read More about SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement.