All Outputs (2)

Evidence for selection in a prokaryote pangenome (2020)
Working Paper
Whelan, F. J., Hall, R. J., & McInerney, J. O. Evidence for selection in a prokaryote pangenome

A pangenome is the complete set of genes (core and accessory) present in a phylogenetic clade. We hypothesize that a pangenome’s accessory gene content is structured and maintained by selection. To test this hypothesis, we interrogated the genomes of... Read More about Evidence for selection in a prokaryote pangenome.

Coinfinder: Detecting significant associations and dissociations in pangenomes (2020)
Journal Article
Whelan, F. J., Rusilowicz, M., & McInerney, J. O. (2020). Coinfinder: Detecting significant associations and dissociations in pangenomes. Microbial Genomics, 6(3), https://doi.org/10.1099/mgen.0.000338

© 2020 The Authors. The accessory genes of prokaryote and eukaryote pangenomes accumulate by horizontal gene transfer, differential gene loss, and the effects of selection and drift. We have developed Coinfinder, a software program that assesses whet... Read More about Coinfinder: Detecting significant associations and dissociations in pangenomes.