All Outputs (3)

Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain (2019)
Journal Article
Knight, M. J., Damion, R. A., McGarry, B. L., Bosnell, R., Jokivarsi, K. T., Gröhn, O. H., …Kauppinen, R. A. (2019). Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain. Biomedical Spectroscopy and Imaging, 8(1-2), 11-28. https://doi.org/10.3233/bsi-190185

BACKGROUND AND OBJECTIVE: In hyperacute ischaemic stroke, T2 of cerebral water increases with time. Quantifying this change may be informative of the extent of tissue damage and onset time. Our objective was to develop a user-unbiased method to measu... Read More about Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain.

Quantifying T2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients (2019)
Journal Article
Damion, R. A., Knight, M. J., McGarry, B. L., Bosnell, R., Jezzard, P., Harston, G. W., …Kauppinen, R. A. (2019). Quantifying T2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients. Physics in Medicine and Biology, 64(9), Article 095016. https://doi.org/10.1088/1361-6560/ab1442

The apparent diffusion coefficient (ADC) of cerebral water, as measured by diffusion MRI, rapidly decreases in ischaemia, highlighting a lesion in acute stroke patients. The MRI T2 relaxation time changes in ischaemic brain such that T2 in ADC lesion... Read More about Quantifying T2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients.

Observation of angular dependence of T1 in the human white matter at 3T (2019)
Journal Article
Knight, M., Damion, R., & Kauppinen, R. (2019). Observation of angular dependence of T1 in the human white matter at 3T. Biomedical Spectroscopy and Imaging, 7(3-4), 125-133. https://doi.org/10.3233/bsi-180183

Background and Objective: Multiple factors including chemical composition and microstructure influence relaxivity of tissue water in vivo. We have quantified T1 in the human white mater (WM) together with diffusion tensor imaging to study a possible... Read More about Observation of angular dependence of T1 in the human white matter at 3T.