All Outputs (3)

Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot (2019)
Journal Article
Jacquot, M., Rao, P. P., Yadav, S., Nomikou, K., Maan, S., Jyothi, Y. K., …Biek, R. (2019). Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot. Virus Evolution, 5(2), Article vez027. https://doi.org/10.1093/ve/vez027

For segmented viruses, rapid genomic and phenotypic changes can occur through the process of reassortment, whereby co-infecting strains exchange entire segments creating novel progeny virus genotypes. However, for many viruses with segmented genomes,... Read More about Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot.

Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR -/- mice (2019)
Journal Article
Fay, P. C., Attoui, H., Batten, C., Mohd Jaafar, F., Lomonossoff, G. P., Daly, J. M., & Mertens, P. P. (2019). Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR -/- mice. Vaccine, 2, Article 100026. https://doi.org/10.1016/j.jvacx.2019.100026

Bluetongue is a severe, economically important disease of ruminants that is widely distributed in tropical and temperate regions around the world. It is associated with major production losses, restrictions of animal movements and trade, as well as c... Read More about Bluetongue virus outer-capsid protein VP2 expressed in Nicotiana Nicotiana benthamiana raises neutralising antibodies and a protective immune response in IFNAR -/- mice.

A low-passage insect-cell isolate of bluetongue virus uses a macropinocytosis-like entry pathway to infect natural target cells derived from the bovine host (2019)
Journal Article
Stevens, L. M., Moffat, K., Cooke, L., Nomikou, K., Mertens, P. P. C., Jackson, T., & Darpel, K. E. (2019). A low-passage insect-cell isolate of bluetongue virus uses a macropinocytosis-like entry pathway to infect natural target cells derived from the bovine host. Journal of General Virology, 100(4), 568-582. https://doi.org/10.1099/jgv.0.001240

Bluetongue virus (BTV) causes an economically important disease in domestic and wildlife ruminants and is transmitted by Culicoides biting midges. In ruminants, BTV has a wide cell tropism that includes endothelial cells of vascular and lymphatic ves... Read More about A low-passage insect-cell isolate of bluetongue virus uses a macropinocytosis-like entry pathway to infect natural target cells derived from the bovine host.