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Testing explosive bubbles with time-varying volatility (2018)
Journal Article
Harvey, D. I., Leybourne, S. J., & Zu, Y. (2019). Testing explosive bubbles with time-varying volatility. Econometric Reviews, 38(10), 1131-1151. https://doi.org/10.1080/07474938.2018.1536099

This paper considers the problem of testing for an explosive bubble in financial data in the presence of time-varying volatility. We propose a weighted least squares-based variant of the Phillips, Wu and Yu (2011) test for explosive autoregressive be... Read More about Testing explosive bubbles with time-varying volatility.

Cell death pathologies: targeting death pathways and the immune system for cancer therapy (2018)
Journal Article
Pentimalli, F., Grelli, S., Di Daniele, N., Melino, G., & Amelio, I. (2019). Cell death pathologies: targeting death pathways and the immune system for cancer therapy. Genes and Immunity, 20(7), 539-554. https://doi.org/10.1038/s41435-018-0052-x

Alterations in the molecular mechanisms of cell death are a common feature of cancer. These alterations enable malignant cells to survive intrinsic death signalling leading to accumulation of genetic aberrations and helping them to cope with adverse... Read More about Cell death pathologies: targeting death pathways and the immune system for cancer therapy.

Temporal relationships between systemic lupus erythematosus and comorbidities (2018)
Journal Article
Kuo, C. F., Chou, I.-J., Rees, F., Grainge, M. J., Lanyon, P., Davenport, G., Mallen, C. D., Chung, T. T., Chen, J. S., Zhang, W., & Doherty, M. (2019). Temporal relationships between systemic lupus erythematosus and comorbidities. Rheumatology, 58(5), 840-848. https://doi.org/10.1093/rheumatology/key335

© The Author(s) 2018. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. Objective: To examine the burden of comorbidities prior to and after the diagnosis of SLE and its impact on mortality.... Read More about Temporal relationships between systemic lupus erythematosus and comorbidities.

A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare (2018)
Journal Article
Liu, L., Hao, F., Morgan, S. P., Correia, R., Norris, A., & Korposh, S. (2019). A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare. Sensing and Bio-Sensing Research, 22, Article 100254. https://doi.org/10.1016/j.sbsr.2018.100254

A reflection-mode carbon dioxide (CO2) fibre optic sensor (FOS) is developed based on the colorimetric change of pH indicator dye thymol blue. The CO2 sensing film comprises thymol blue and tetramethylammonium hydroxide in the form of an ion pair dop... Read More about A reflection-mode fibre-optic sensor for breath carbon dioxide measurement in healthcare.

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 (2018)
Journal Article
Tzelepis, K., De Braekeleer, E., Aspris, D., Barbieri, I., Vijayabaskar, M. S., Liu, W.-H., Gozdecka, M., Metzakopian, E., Toop, H. D., Dudek, M., Robson, S. C., Hermida-Prado, F., Yang, Y. H., Babaei-Jadidi, R., Garyfallos, D. A., Ponstingl, H., Dias, J. M. L., Gallipoli, P., Seiler, M., Buonamici, S., …Vassiliou, G. S. (2018). SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nature Communications, 9(1), Article 5378. https://doi.org/10.1038/s41467-018-07620-0

We recently identified the splicing kinase gene SRPK1 as a genetic vulnerability of acute myeloid leukemia (AML). Here, we show that genetic or pharmacological inhibition of SRPK1 leads to cell cycle arrest, leukemic cell differentiation and prolonge... Read More about SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.

The mathematical backgrounds of undergraduates from England (2018)
Journal Article
Hodgen, J., Adkins, M., & Tomei, A. (2020). The mathematical backgrounds of undergraduates from England. Teaching Mathematics and its Applications, 39(1), 38–60. https://doi.org/10.1093/teamat/hry017

Participation in any kind of mathematical study during upper secondary education in England is significantly lower than in other educational systems. As a result, many English students enter university at age 18 or 19 having not studied mathematics f... Read More about The mathematical backgrounds of undergraduates from England.

Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1 (2018)
Journal Article
Sanchez, J., e Huma, Z., Lane, J., Liu, X., Bridgford, J. L., Payne, R. J., Canals, M., & Stone, M. J. (2018). Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1. Journal of Biological Chemistry, 294(10), 3464-3475. https://doi.org/10.1074/jbc.ra118.006535

© 2019 Sanchez et al. Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc. Interactions between secreted immune proteins called chemokines and their cognate G protein– coupled receptors regulate the t... Read More about Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1.

Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma (2018)
Journal Article
Burchill, S. A., Ziegler, D. S., Etchevers, H. C., Norris, M. D., Cheng, P. N., McConville, C. M., Berry, A. M., Gamble, L. D., Fultang, L., Gamble, L. D., Gneo, L., Berry, A. M., Egan, S. A., De Bie, F., Yogev, O., Eden, G. L., Booth, S., Brownhill, S., Vardon, A., McConville, C. M., …Mussai, F. (2019). Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma. Cancer Research, 79(3), 611-624. https://doi.org/10.1158/0008-5472.CAN-18-2139

© 2018 American Association for Cancer Research. Neuroblastoma is the most common childhood solid tumor, yet the prognosis for high-risk disease remains poor. We demonstrate here that arginase 2 (ARG2) drives neuroblastoma cell proliferation via regu... Read More about Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma.

Interventions for treating wrist fractures in children (Review) (2018)
Journal Article
H.G. Handoll, H., Elliott, J., Iheozor‐Ejiofor, Z., Hunter, J., & Karantana, A. (2018). Interventions for treating wrist fractures in children (Review). Cochrane Database of Systematic Reviews, 2018(12), 1-239. https://doi.org/10.1002/14651858.CD012470.pub2

© 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background: Wrist fractures, involving the distal radius, are the most common fractures in children. Most are buckle fractures, which are stable fractures, unlike greenstick an... Read More about Interventions for treating wrist fractures in children (Review).

In-situ XPS analysis of the atomic layer deposition of aluminium oxide on titanium dioxide (2018)
Journal Article
Temperton, R., Gibson, A., & O'Shea, J. (2018). In-situ XPS analysis of the atomic layer deposition of aluminium oxide on titanium dioxide. Physical Chemistry Chemical Physics, 21(3), 1393-1398. https://doi.org/10.1039/c8cp06912c

Ultra-thin aluminium oxide was grown on a rutile titanium dioxide surface by atomic layer deposition using trimethylaluminium and water precursors. This process, carried out using realistic temperatures and pressures (1 mbar, 450 K), was monitored in... Read More about In-situ XPS analysis of the atomic layer deposition of aluminium oxide on titanium dioxide.

Bovine neonatal monocytes display phenotypic differences compared with adults after challenge with the infectious abortifacient agent Neospora caninum (2018)
Journal Article
Sharma, P., Hartley, C. S., Haque, M., Coffey, T. J., Egan, S. A., & Flynn, R. J. (2018). Bovine neonatal monocytes display phenotypic differences compared with adults after challenge with the infectious abortifacient agent Neospora caninum. Frontiers in Immunology, 9, Article 3011. https://doi.org/10.3389/fimmu.2018.03011

The neonatal period represents a window of susceptibility for ruminants given the abundance of infectious challenges in their environment. Maternal transfer of immunity does not occur in utero but post-parturition, however this does not compensate fo... Read More about Bovine neonatal monocytes display phenotypic differences compared with adults after challenge with the infectious abortifacient agent Neospora caninum.

Closure of the Bering Strait caused Mid-Pleistocene Transition cooling (2018)
Journal Article
Kender, S., Ravelo, A. C., Worne, S., Swann, G. E. A., Leng, M. J., Asahi, H., Becker, J., Detlef, H., Aiello, I. W., Andreasen, D., & Hall, I. R. (2018). Closure of the Bering Strait caused Mid-Pleistocene Transition cooling. Nature Communications, 9(1), Article 5386. https://doi.org/10.1038/s41467-018-07828-0

The Mid-Pleistocene Transition (MPT) is characterised by cooling and lengthening glacial cycles from 600–1200 ka, thought to be driven by reductions in glacial CO2 in particular from ~900 ka onwards. Reduced high latitude upwelling, a process that re... Read More about Closure of the Bering Strait caused Mid-Pleistocene Transition cooling.

Portfolio sales and signaling (2018)
Journal Article
Bougheas, S., & Worrall, T. (2019). Portfolio sales and signaling. Journal of Banking and Finance, 99, 182-191. https://doi.org/10.1016/j.jbankfin.2018.12.008

This paper extends the DeMarzo and Duffie (1999) signaling model from single sales to portfolio sales. It shows that the extended model can account for retention of low quality assets and help explain why retained assets may be of varying quality.

The effects of aging on hepatic microsomal scaling factor and hepatocellularity number in the horse (2018)
Journal Article
Shibany, K. A., Tötemeyer, S., Pratt, S. L., & Paine, S. W. (2018). The effects of aging on hepatic microsomal scaling factor and hepatocellularity number in the horse. Xenobiotica, 48(12), 1237-1244. https://doi.org/10.1080/00498254.2017.1413263

Scaling factor values for the in vitro-in vivo extrapolation of hepatic metabolic clearance for xenobiotics have not yet been determined in horses. Scaling factors were determined by comparing the total protein and or CYP P450 content in microsomes a... Read More about The effects of aging on hepatic microsomal scaling factor and hepatocellularity number in the horse.

Decision-making experiences of patients with end-stage kidney disease (ESKD) regarding treatment in Ghana: a qualitative study (2018)
Journal Article
Boateng, E. A., East, L., & Evans, C. (2018). Decision-making experiences of patients with end-stage kidney disease (ESKD) regarding treatment in Ghana: a qualitative study. BMC Nephrology, 19, Article 371. https://doi.org/10.1186/s12882-018-1175-z

Background: This is the first qualitative study to explore patient decision-making regarding end-stage kidney disease (ESKD) treatment in sub-Saharan Africa. The study addresses an important gap in the literature concerning choice and decision-making... Read More about Decision-making experiences of patients with end-stage kidney disease (ESKD) regarding treatment in Ghana: a qualitative study.

Understanding the effect of indoor air pollution on pneumonia in children under five in low and middle income countries: a systematic review of evidence (2018)
Journal Article
Adaji, E. E., Ekezie, W., Clifford, M., & Phalkey, R. (2019). Understanding the effect of indoor air pollution on pneumonia in children under five in low and middle income countries: a systematic review of evidence. Environmental Science and Pollution Research, 26(4), 3208–3225. https://doi.org/10.1007/s11356-018-3769-1

Background

Exposure to indoor air pollution increases the risk of pneumonia in children, accounting for about a million deaths globally. This study investigates the individual effect of solid fuel, carbon monoxide
(CO), black carbon (BC) and PM2.... Read More about Understanding the effect of indoor air pollution on pneumonia in children under five in low and middle income countries: a systematic review of evidence.

Diatom evidence of 20th century ecosystem change in Lake Baikal, Siberia (2018)
Journal Article
Roberts, S., Swann, G., McGowan, S., Panizzo, V., Vologina, E., Sturm, M., & Mackay, A. (2018). Diatom evidence of 20th century ecosystem change in Lake Baikal, Siberia. PLoS ONE, 13(12), Article e020876. https://doi.org/10.1371/journal.pone.0208765

Lake Baikal has been experiencing limnological changes from recent atmospheric warming since the 1950s, with rising lake water temperatures, reduced ice cover duration and reduced lake surface-water mixing due to stronger thermal stratification. This... Read More about Diatom evidence of 20th century ecosystem change in Lake Baikal, Siberia.

Beauty is in the eye of the beholder: the appraisal of facial attractiveness and its relation to conscious awareness (2018)
Journal Article
Tsikandilakis, M., Bali, P., & Chapman, P. (2019). Beauty is in the eye of the beholder: the appraisal of facial attractiveness and its relation to conscious awareness. Perception, 48(1), 72-92. https://doi.org/10.1177/0301006618813035

Previous research suggests that facial attractiveness relies on features such as symmetry, averageness and above-average sexual dimorphic characteristics. Due to the evolutionary and sociobiological value of these characteristics, it has been suggest... Read More about Beauty is in the eye of the beholder: the appraisal of facial attractiveness and its relation to conscious awareness.