All Outputs (4387)

Assessing the impacts of 1.5 °C global warming–simulation protocol of the Inter-Sectoral Impact Model Intercomparison Project (ISIMIP2b) (2017)
Journal Article

In Paris, France, December 2015, the Conference of the Parties (COP) to the United Nations Framework Convention on Climate Change (UNFCCC) invited the Intergovernmental Panel on Climate Change (IPCC) to provide a "special report in 2018 on the impact... Read More about Assessing the impacts of 1.5 °C global warming–simulation protocol of the Inter-Sectoral Impact Model Intercomparison Project (ISIMIP2b).

New type I ancient compact solutions of the Yamabe flow (2017)
Journal Article

We construct new ancient compact solutions to the Yamabe flow. Our solutions are rotationally symmetric and converge, as t???, to two self-similar complete non-compact solutions to the Yamabe flow moving in opposite directions. They are type I ancien... Read More about New type I ancient compact solutions of the Yamabe flow.

Engineering substrate promiscuity in halophilic alcohol dehydrogenase (HvADH2) by in silico design (2017)
Journal Article

An alcohol dehydrogenase from the halophilic archaeon Haloferax volcanii (HvADH2) has been engineered by rational design to broaden its substrate scope towards the conversion of a range of aromatic substrates, including flurbiprofenol, that is an int... Read More about Engineering substrate promiscuity in halophilic alcohol dehydrogenase (HvADH2) by in silico design.

A molecular signature of dormancy in CD34+CD38- acute myeloid leukaemia cells (2017)
Journal Article

Dormant leukaemia initiating cells in the bone marrow niche are a crucial therapeutic target for total eradication of acute myeloid leukaemia. To study this cellular subset we created and validated an in vitro model employing the cell line TF-1a, tre... Read More about A molecular signature of dormancy in CD34+CD38- acute myeloid leukaemia cells.

Towards a coherent implementation of safe building laws and regulations in Cameroon: law, gowernance and institutional imperatives (2017)
Journal Article

Over the last decade a sustained pattern of building collapse and fire outbreaks has been observed in various West African countries such as Cameroon, Nigeria and Ghana. This has become a serious concern amongst building practitioners and to the publ... Read More about Towards a coherent implementation of safe building laws and regulations in Cameroon: law, gowernance and institutional imperatives.

Generalization and modelling of rigid polyisocyanurate foam reaction kinetics, structural units effect, and cell configuration mechanism (2017)
Journal Article

PIR/PUR ratio was derived from differential manipulation of generalized polyisocyanurate kinetic model. The structural unit effects on polymerization of isocyanurate, urethane and urea linkages were evaluated based on Mayo-Lewise tercopolymerization... Read More about Generalization and modelling of rigid polyisocyanurate foam reaction kinetics, structural units effect, and cell configuration mechanism.

A Lesser Evil? The European Agenda on Migration and the Use of Funding for Migration Control (2017)
Book Chapter

Explanatory abstractions (2017)
Journal Article

A number of philosophers have recently suggested that some abstract, plausibly non-causal and/or mathematical, explanations explain in a way that is radically different from the way causal explanation explain. Namely, while causal explanations explai... Read More about Explanatory abstractions.

Scientific Synergy Between LSST and Euclid (2017)
Working Paper

Euclid and the Large Synoptic Survey Telescope (LSST) are poised to dramatically change the astronomy landscape early in the next decade. The combination of high cadence, deep, wide-field optical photometry from LSST with high resolution, wide-field... Read More about Scientific Synergy Between LSST and Euclid.

A multi-disciplinary perspective on emergent and future innovations in peer review [version 3; peer review: 2 approved] (2017)
Journal Article

Peer review of research articles is a core part of our scholarly communication system. In spite of its importance, the status and purpose of peer review is often contested. What is its role in our modern digital research and communications infrastruc... Read More about A multi-disciplinary perspective on emergent and future innovations in peer review [version 3; peer review: 2 approved].

Analysis of Fractional-Slot Concentrated Winding PM Vernier Machines With Regular Open-Slot Stators (2017)
Journal Article

Permanent magnet (PM) vernier (PMV) machines have been extensively researched for direct-drive applications due to their inherently high torque density. This paper presents a quantitative investigation on fractional-slot concentrated winding PMV (FSC... Read More about Analysis of Fractional-Slot Concentrated Winding PM Vernier Machines With Regular Open-Slot Stators.

The challenges of training, support and assessment of healthcare support workers: a qualitative study of experiences in three English acute hospitals (2017)
Journal Article

Background Ever-growing demands on care systems have increased reliance on healthcare support workers. In the UK, their training has been variable, but organisation-wide failures in care have prompted questions about how this crucial section of the... Read More about The challenges of training, support and assessment of healthcare support workers: a qualitative study of experiences in three English acute hospitals.

Survival of corneal nerve/sheath structures in organ-cultured donor corneas (2017)
Journal Article

Purpose To study the morphology of human corneal nerves in eye bank organ‐cultured corneas and in corneal grafts post‐transplantation. Methods Thirty‐seven organ‐cultured corneas were divided into: Group‐A, anterior 300–400 μm of 20 corneas used... Read More about Survival of corneal nerve/sheath structures in organ-cultured donor corneas.

Countering Extremism in British Schools?: The Truth about the Birmingham Trojan Horse Affair (2017)
Book

In 2014 an investigation into an alleged plot to ‘Islamify’ several state schools in Birmingham began. Known as the ‘Trojan Horse’ affair, this caused a previously highly successful school to be vilified. Holmwood, an expert witness in the profess... Read More about Countering Extremism in British Schools?: The Truth about the Birmingham Trojan Horse Affair.

Development of the short version of the Scales of General Well-Being: the 14-item SGWB (2017)
Journal Article

The Scales of General Well-Being (SGWB, Longo, Coyne, & Joseph, 2017) is a 65-item tool assessing fourteen different constructs. The aim of this study was to develop a short 14-item version. One item was chosen from each of the fourteen scales follow... Read More about Development of the short version of the Scales of General Well-Being: the 14-item SGWB.

Feature-based characterisation of signature topography in laser powder bed fusion of metals (2017)
Journal Article

The use of state-of-the-art areal topography measurement instrumentation allows for a high level of detail in the acquisition of topographic information at micrometric scales. The three-dimensional geometric models of surface topography obtained from... Read More about Feature-based characterisation of signature topography in laser powder bed fusion of metals.

Draught beer hygiene: a forcing test to assess quality (2017)
Journal Article

The quality of draught beer is important to consumers but can be inconsistent, ranging from excellent through to unacceptable. The few but dated studies of draught beer quality have focused on the number of microorganisms that are present in the pro... Read More about Draught beer hygiene: a forcing test to assess quality.

Riemann solution for a class of morphodynamic shallow water dam-break problems (2017)
Journal Article

This paper investigates a family of dam-break problems over an erodible bed. The hydrodynamics are described by the shallow water equations, and the bed change by a sediment conservation equation, coupled to the hydrodynamics by a sediment transport... Read More about Riemann solution for a class of morphodynamic shallow water dam-break problems.

Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke (2017)
Journal Article

Background: Cooling may reduce infarct size and improve neurological outcomes in patients with ischaemic stroke. In phase II trials, cooling awake patients with ischaemic stroke has been shown to be feasible and safe, but the effects in functional ou... Read More about Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke.

Representation in Wales: an empirical analysis of the policy divisions between voters and candidates (2017)
Journal Article

Politics in Wales is often portrayed as being relatively consensual when compared with the rest of the United Kingdom and enjoying healthy levels of trust between voters and elites. Recent events like the decision of Welsh voters to reject the Europe... Read More about Representation in Wales: an empirical analysis of the policy divisions between voters and candidates.