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Bidirectional effects of cannabidiol on contextual fear memory extinction (2016)
Journal Article
Song, C., Stevenson, C. W., Guimaraes, F. S., & Lee, J. L. (2016). Bidirectional effects of cannabidiol on contextual fear memory extinction. Frontiers in Pharmacology, 7(493), https://doi.org/10.3389/fphar.2016.00493

Cannabidiol (CBD) has been established to have both acute and long-lasting effects to reduce fear memory expression. The long-lasting impact might be mediated by an enhancement of memory extinction or an impairment of memory reconsolidation. Here, we... Read More about Bidirectional effects of cannabidiol on contextual fear memory extinction.

Cannabidiol regulation of learned fear: implications for treating anxiety-related disorders (2016)
Journal Article
Jurkus, R., Day, H. L., Guimaraes, F. S., Lee, J. L., Bertoglio, L. J., & Stevenson, C. W. (2016). Cannabidiol regulation of learned fear: implications for treating anxiety-related disorders. Frontiers in Pharmacology, 7(454), https://doi.org/10.3389/fphar.2016.00454

Anxiety and trauma-related disorders are psychiatric diseases with a lifetime prevalence of up to 25%. Phobias and post-traumatic stress disorder (PTSD) are characterized by abnormal and persistent memories of fear-related contexts and cues. The effe... Read More about Cannabidiol regulation of learned fear: implications for treating anxiety-related disorders.

Sex differences in discriminating between cues predicting threat and safety (2016)
Journal Article
Day, H. L., Reed, M. M., & Stevenson, C. W. (2016). Sex differences in discriminating between cues predicting threat and safety. Neurobiology of Learning and Memory, 133, 196-203. https://doi.org/10.1016/j.nlm.2016.07.014

Post-traumatic stress disorder (PTSD) is more prevalent in women than men. PTSD is characterized by overgeneralization of fear to innocuous stimuli and involves impaired inhibition of learned fear by cues that predict safety. While evidence indicates... Read More about Sex differences in discriminating between cues predicting threat and safety.

Sex differences in learned fear expression and extinction involve altered gamma oscillations in medial prefrontal cortex (2016)
Journal Article
Fenton, G., Halliday, D., Mason, R., Bredy, T. W., & Stevenson, C. W. (2016). Sex differences in learned fear expression and extinction involve altered gamma oscillations in medial prefrontal cortex. Neurobiology of Learning and Memory, 135, https://doi.org/10.1016/j.nlm.2016.06.019

Sex differences in learned fear expression and extinction involve the medial prefrontal cortex (mPFC). We recently demonstrated that enhanced learned fear expression during auditory fear extinction and its recall is linked to persistent theta activat... Read More about Sex differences in learned fear expression and extinction involve altered gamma oscillations in medial prefrontal cortex.

Non-parametric directionality analysis: extension for removal of a single common predictor and application to time series (2016)
Journal Article
Halliday, D. M., Senik, M. H., Stevenson, C. W., & Mason, R. (2016). Non-parametric directionality analysis: extension for removal of a single common predictor and application to time series. Journal of Neuroscience Methods, 268, https://doi.org/10.1016/j.jneumeth.2016.05.008

BACKGROUND: The ability to infer network structure from multivariate neuronal signals is central to computational neuroscience. Directed network analyses typically use parametric approaches based on auto-regressive (AR) models, where networks are con... Read More about Non-parametric directionality analysis: extension for removal of a single common predictor and application to time series.