All Outputs (3)

Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis (2015)
Journal Article
Negm, O. H., Hamed, M. R., Dilnot, E. M., Shone, C. C., Marszalowska, I., Lynch, M., …Monaghan, T. M. (2015). Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis. Clinical and Vaccine Immunology, 22(9), 1033-1039. https://doi.org/10.1128/CVI.00190-15

Clostridium difficile is an anaerobic, Gram-positive, and spore-forming bacterium that is the leading worldwide infective cause of hospital-acquired and antibiotic-associated diarrhea. Several studies have reported associations between humoral immuni... Read More about Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis.

Pathogenesis of Clostridium difficile infection and its potential role in inflammatory bowel disease (2015)
Journal Article
Monaghan, T. M., Cockayne, A., & MAHIDA, Y. (2015). Pathogenesis of Clostridium difficile infection and its potential role in inflammatory bowel disease. Inflammatory Bowel Diseases, 21(8), doi:10.1097/MIB.0000000000000461

mild diarrhea to life-threatening colitis. Over the last 15 years, there has been a marked increase in the incidence of C. difficile infection, which predominantly affects elderly patients on antibiotics. More recently, there has been significant int... Read More about Pathogenesis of Clostridium difficile infection and its potential role in inflammatory bowel disease.

New perspectives in Clostridium difficile disease pathogenesis (2015)
Journal Article
Monaghan, T. M. (2015). New perspectives in Clostridium difficile disease pathogenesis. Infectious Disease Clinics of North America, 29(1), 1-11. doi:10.1016/j.idc.2014.11.007

Clostridium difficile is a gram-positive, endospore-forming, anaerobic, gastrointestinal pathogen that is the leading worldwide cause of hospital-acquired infective diarrhea.1 C. difficile exerts its major pathologic effects through the action of its... Read More about New perspectives in Clostridium difficile disease pathogenesis.