Pharmacological analysis and structure determination of 7-methylcyanopindolol–bound b1-adrenergic receptor
(2015)
Journal Article
Sato, T., Baker, J. G., Warne, T., Brown, G. A., Leslie, A., Congreve, M., & Tate, C. G. (2015). Pharmacological analysis and structure determination of 7-methylcyanopindolol–bound b1-adrenergic receptor. Molecular Pharmacology, 88(6), https://doi.org/10.1124/mol.115.101030
Comparisons between structures of the b1-adrenergic receptor (AR) bound to either agonists, partial agonists, or weak partial agonists led to the proposal that rotamer changes of Ser5.46, coupled to a contraction of the binding pocket, are sufficient... Read More about Pharmacological analysis and structure determination of 7-methylcyanopindolol–bound b1-adrenergic receptor.