Differential spontaneous folding of mycolic acids from Mycobacterium tuberculosis
(2013)
Journal Article
All Outputs (1292)
A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine (2013)
Journal Article
Cdk9 is a key elongation factor for RNA transcription and functions by phosphorylating the C-terminal domain of RNA polymerase II. Here we present direct evidence that cdk9 is important for cancer cell survival and describe the characterization of th... Read More about A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine.
Infobiotics workbench: a P systems based tool for systems and synthetic biology (2013)
Book Chapter
This chapter gives an overview of an integrated software suite, the Infobiotics Workbench, which is based on a novel spatial discrete-stochastic P systems modelling framework. The Workbench incorporates three important features, simulation, model che... Read More about Infobiotics workbench: a P systems based tool for systems and synthetic biology.
This chapter will ascertain the intentions of the drafters of the European Convention on Human Rights (hereafter the ECHR or Convention) and then examine a number of factors that have resulted in the judicial expansion of the rights and freedoms ensh... Read More about Between the will of the contracting parties and the needs of today: Extending the scope of convention rights and freedoms beyond what could have been foreseen by the drafters of the echr.
A structural analysis of greening the supplier, environmental performance and competitive advantage (2013)
Journal Article
A clear research need has been identified to confirm the structural relationships between greening the supplier, enhanced environmental performance and improved competitive advantage, to provide an impetus for firms to green their suppliers. A mail s... Read More about A structural analysis of greening the supplier, environmental performance and competitive advantage.
Microwave synthesis of magnetically separable ZnFe2O4-reduced graphene oxide for wastewater treatment (2013)
Journal Article
A magnetically separable ZnFe2O4-reduced graphene oxide (rGO) nano-composite was synthesised via a microwave method. Field emission scanning electron microscopy images of the nano-composite showed a uniform dispersion of nanoparticles on the rGO shee... Read More about Microwave synthesis of magnetically separable ZnFe2O4-reduced graphene oxide for wastewater treatment.
Kinetics and mechanism of G protein-coupled receptor activation (2013)
Journal Article
The activation of a G protein-coupled receptor is generally triggered by binding of an agonist to the receptor's binding pocket, or, in the case of rhodopsin, by light-induced changes of the pre-bound retinal. This is followed by a series of a confor... Read More about Kinetics and mechanism of G protein-coupled receptor activation.
Ascorbate Efflux as a New Strategy for Iron Reduction and Transport in Plants (2013)
Journal Article
On the epidemic of financial crises (2013)
Journal Article
The paper proposes a framework for modelling financial contagion that is based on susceptible-infected-recovered transmission models from epidemic theory. This class of models addresses two important features of contagion modelling, which are a commo... Read More about On the epidemic of financial crises.
A qualitative investigation of the impact of peer to peer online support for women living with Polycystic Ovary Syndrome (2013)
Journal Article
Background: Polycystic Ovary Syndrome is a common, chronic condition which affects women living with the condition both physically and psychologically. Social support may be beneficial to sufferers in coping with chronic conditions and the Internet i... Read More about A qualitative investigation of the impact of peer to peer online support for women living with Polycystic Ovary Syndrome.
The influence of circulating anti-Müllerian hormone on ovarian responsiveness to ovulation induction with gonadotrophins in women with polycystic ovarian syndrome: a pilot study (2013)
Journal Article
Background Women with polycystic ovarian syndrome (PCOS) are known to have elevated circulating Anti-Müllerian hormone (AMH), which has been found to desensitize ovarian follicles to follicle stimulating hormone (FSH). The purpose of this study was... Read More about The influence of circulating anti-Müllerian hormone on ovarian responsiveness to ovulation induction with gonadotrophins in women with polycystic ovarian syndrome: a pilot study.
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis (2013)
Journal Article
Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we demonstrate a role for inte... Read More about IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
Multisectoral climate impact hotspots in a warming world (2013)
Journal Article
The impacts of global climate change on different aspects of humanity's diverse life-support systems are complex and often difficult to predict. To facilitate policy decisions on mitigation and adaptation strategies, it is necessary to understand, qu... Read More about Multisectoral climate impact hotspots in a warming world.
Constraints and potentials of future irrigation water availability on agricultural production under climate change (2013)
Journal Article
We compare ensembles of water supply and demand projections from 10 global hydrological models and six global gridded crop models. These are produced as part of the Inter-Sectoral Impacts Model Intercomparison Project, with coordination from the Agri... Read More about Constraints and potentials of future irrigation water availability on agricultural production under climate change.
Multimodel assessment of water scarcity under climate change (2013)
Journal Article
Water scarcity severely impairs food security and economic prosperity in many countries today. Expected future population changes will, in many countries as well as globally, increase the pressure on available water resources. On the supply side, ren... Read More about Multimodel assessment of water scarcity under climate change.
Liquid film thickness behaviour within a large diameter vertical 180° return bend (2013)
Journal Article
Experimental results of liquid film thickness distribution of an air-water mixture flowing through a vertical 180° return bend are reported. Measurements of liquid film thickness were achieved using flush mounted pin and parallel wire probes. The ben... Read More about Liquid film thickness behaviour within a large diameter vertical 180° return bend.
C=N-containing azaarenes as activating groups in enantioselective catalysis (2013)
Journal Article
Nitrogen-containing aromatic heterocycles (azaarenes) are of widespread chemical significance, and chi-ral compounds containing azaarenes feature prominently in pharmaceuticals, agrochemicals, and natural products. This Perspective highlights the use... Read More about C=N-containing azaarenes as activating groups in enantioselective catalysis.
Dirac Operators on Noncommutative Curved Spacetimes (2013)
Journal Article
We study the notion of a Dirac operator in the framework of twist-deformed noncommutative geometry. We provide a number of well-motivated candidate constructions and propose a minimal set of axioms that a noncommutative Dirac operator should satisfy.... Read More about Dirac Operators on Noncommutative Curved Spacetimes.
The role of hedonism in ethical tourism (2013)
Journal Article
This paper investigates the role of emotion in the ethical choice processes of tourists. Specifically, it explores how hedonism is experienced and the links between hedonic experiences and intentions for future ethical behaviour. It adopts an interpr... Read More about The role of hedonism in ethical tourism.
Cytokinin signalling inhibitory fields provide robustness to phyllotaxis (2013)
Journal Article
How biological systems generate reproducible patterns with high precision is a central question in science. The shoot apical meristem (SAM), a specialized tissue producing plant aerial organs, is a developmental system of choice to address this quest... Read More about Cytokinin signalling inhibitory fields provide robustness to phyllotaxis.