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All Outputs (3)

Altered placental expression of kisspeptin and its receptor in pre-eclampsia (2012)
Journal Article
Cartwright, J. E., & Williams, P. J. (2012). Altered placental expression of kisspeptin and its receptor in pre-eclampsia. Journal of Endocrinology, 214(1), https://doi.org/10.1530/JOE-12-0091

Kisspeptin, originally identified as metastatin, important in preventing cancer metastasis, has more recently been shown to be important in pregnancy. Roles indicated for kisspeptin in pregnancy include regulating trophoblast invasion and migration d... Read More about Altered placental expression of kisspeptin and its receptor in pre-eclampsia.

The role of genetics in pre-eclampsia and potential pharmacogenomic interventions (2012)
Journal Article
Williams, P. J., & Morgan, L. (2012). The role of genetics in pre-eclampsia and potential pharmacogenomic interventions. Pharmacogenomics and Personalized Medicine, 2012:5, https://doi.org/10.2147/PGPM.S23141

The pregnancy-specific condition pre-eclampsia not only affects the health of mother and baby during pregnancy but also has long-term consequences, increasing the chances of cardiovascular disease in later life. It is accepted that pre-eclampsia has... Read More about The role of genetics in pre-eclampsia and potential pharmacogenomic interventions.

Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia (2012)
Journal Article
Williams, P. J., Mistry, H. D., & Morgan, L. (2012). Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia. Pregnancy Hypertension, 2(2), https://doi.org/10.1016/j.preghy.2011.12.001

The transport of folate across the placenta involves a number of different receptors including folate receptor-alpha (FR-?), reduced folate carrier (RFC) and proton coupled folate transporter (PCFT). In addition there are a number of ATP-dependent tr... Read More about Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia.