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Delivering Employment Services to Vulnerable Customers: A Case Study of the UK's Employment Service (2012)
Journal Article
Stafford, B., Roberts, S., & Duffy, D. (2012). Delivering Employment Services to Vulnerable Customers: A Case Study of the UK's Employment Service. Social Policy and Society, 11(4), 495-506. https://doi.org/10.1017/S1474746412000206

This article explores the impact of a more individualised public employment service on vulnerable people. It analyses a system Jobcentre Plus implemented in 2008, Accessing Jobcentre Plus Customer Services (AJCS), to improve customer services by mini... Read More about Delivering Employment Services to Vulnerable Customers: A Case Study of the UK's Employment Service.

A moment of transformative learning: creating a disorientating dilemma for a health care student using video feedback (2012)
Journal Article
James, D. M., Collins, L. C., & Samoylova, E. (2012). A moment of transformative learning: creating a disorientating dilemma for a health care student using video feedback. Journal of Transformative Education, 10(4), https://doi.org/10.1177/1541344613480562

This study describes a moment during clinical supervision when a student speech and language therapist reported that she had a moment of illumination that changed her trajectory from failing her clinical placement to passing it. The student’s self-re... Read More about A moment of transformative learning: creating a disorientating dilemma for a health care student using video feedback.

"Vulnerability hotspots": Integrating socio-economic and hydrological models to identify where cereal production may decline in the future due to climate change induced drought (2012)
Journal Article
Fraser, E. D., Simelton, E., Termansen, M., Gosling, S. N., & South, A. (2013). "Vulnerability hotspots": Integrating socio-economic and hydrological models to identify where cereal production may decline in the future due to climate change induced drought. Agricultural and Forest Meteorology, 170, 195-205. https://doi.org/10.1016/j.agrformet.2012.04.008

The purpose of this paper is to identify which of the world's cereal producing regions are likely to become vulnerable to climate change over the 21st century by identifying those regions that will be (1) exposed to climatic stress and (2) have a lim... Read More about "Vulnerability hotspots": Integrating socio-economic and hydrological models to identify where cereal production may decline in the future due to climate change induced drought.

A three-dimensional model of residential energy consumer archetypes for local energy policy design in the UK (2012)
Journal Article
Zhang, T., Siebers, P., & Aickelin, U. (2012). A three-dimensional model of residential energy consumer archetypes for local energy policy design in the UK. Energy Policy, 47, 102-110. https://doi.org/10.1016/j.enpol.2012.04.027

This paper reviews major studies in three traditional lines of research in residential energy consumption in the UK, i.e. economic/infrastructure, behaviour, and load profiling. Based on the review the paper proposes a three-dimensional model for arc... Read More about A three-dimensional model of residential energy consumer archetypes for local energy policy design in the UK.

Sustained translational repression by eIF2α-P mediates prion neurodegeneration (2012)
Journal Article
Moreno, J. A., Radford, H., Peretti, D., Steinert, J. R., Verity, N., Martin, M. G., …Mallucci, G. R. (2012). Sustained translational repression by eIF2α-P mediates prion neurodegeneration. Nature, 485(7399), 507-511. https://doi.org/10.1038/nature11058

The mechanisms leading to neuronal death in neurodegenerative disease are poorly understood. Many of these disorders, including Alzheimer's, Parkinson's and prion diseases, are associated with the accumulation of misfolded disease-specific proteins.... Read More about Sustained translational repression by eIF2α-P mediates prion neurodegeneration.

Genome-wide association study to identify genetic determinants of severe asthma (2012)
Journal Article
Wan, Y., Shrine, N., Soler Artigas, M., Wain, L., Blakey, J., Moffatt, M., …Hall, I. P. (2012). Genome-wide association study to identify genetic determinants of severe asthma. Thorax, 67(9), https://doi.org/10.1136/thoraxjnl-2011-201262

Background The genetic basis for developing asthma has been extensively studied. However, association studies to date have mostly focused on mild to moderate disease and genetic risk factors for severe asthma remain unclear. Objective To identify co... Read More about Genome-wide association study to identify genetic determinants of severe asthma.

Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study (2012)
Journal Article
McWilliams, D. F., Zhang, W., Mansell, J. S., Kiely, P. D., Young, A., & Walsh, D. A. (2012). Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study. Arthritis Care and Research, 64(10), https://doi.org/10.1002/acr.21723

Objective: To investigate possible predictors for lack of pain improvement after 1 year of treatment for early rheumatoid arthritis (RA). Methods: The Early Rheumatoid Arthritis Network (ERAN) database was used for analysis of baseline and 1-year... Read More about Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study.

Interface dynamics in planar neural field models (2012)
Journal Article
Coombes, S., Schmidt, H., & Bojak, I. (2012). Interface dynamics in planar neural field models. Journal of Mathematical Neuroscience, 2(1), 1-46. https://doi.org/10.1186/2190-8567-2-9

Neural field models describe the coarse-grained activity of populations of interacting neurons. Because of the laminar structure of real cortical tissue they are often studied in two spatial dimensions, where they are well known to generate rich patt... Read More about Interface dynamics in planar neural field models.

An interpretative phenomenological analysis of the patient experience of awake craniotomy: brain tumour diagnosis to discharge (2012)
Journal Article
Fletcher, K. J., das Nair, R., Macniven, J. A., Basu, S., & Byrne, P. (2012). An interpretative phenomenological analysis of the patient experience of awake craniotomy: brain tumour diagnosis to discharge. British Journal of Health Psychology, 17(4), https://doi.org/10.1111/j.2044-8287.2012.02079.x

Objectives. Previous research exploring the patient experience of awake craniotomy (AC) has yielded contrasting accounts. The current study aimed to explore the lived experience of having undergone an AC in the United Kingdom. Design. This was a q... Read More about An interpretative phenomenological analysis of the patient experience of awake craniotomy: brain tumour diagnosis to discharge.

Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death (2012)
Journal Article
Rogers, H. A., Kilday, J., Mayne, C., Ward, J., Adamowicz-Brice, M., Schwalbe, E. C., …Grundy, R. G. (2012). Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death. Acta Neuropathologica, 123(5), https://doi.org/10.1007/s00401-011-0904-1

Epigenetic alterations, including methylation, have been shown to be an important mechanism of gene silencing in cancer. Ependymoma has been well characterized at the DNA copy number and mRNA expression levels. However little is known about DNA methy... Read More about Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.

On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry (2012)
Journal Article
Pang, V., Counillon, L., Lagadic-Gossmann, D., Poet, M., Lacroix, J., Sergent, O., …Rauch, C. (2012). On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry. Cell Biochemistry and Biophysics, 63(1), https://doi.org/10.1007/s12013-012-9340-7

The sodium-proton exchanger 1 (NHE-1) is a membrane transporter that exchanges Na+ for H+ ion across the membrane of eukaryotic cells. It is cooperatively activated by intracellular protons, and this allosteric regulation is modulated by the biophysi... Read More about On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry.

Opposing effects of 5,7-DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli (2012)
Journal Article
Nelson, A. J., Thur, K. E., Marsden, C. A., & Cassaday, H. J. (2012). Opposing effects of 5,7-DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli. International Journal of Neuropsychopharmacology, 15(4), https://doi.org/10.1017/S1461145711000599

There is good evidence that forebrain serotonergic systems modulate cognitive flexibility. Latent inhibition (LI) is a cross-species phenomenon which manifests as poor conditioning to a stimulus that has previously been experienced without consequenc... Read More about Opposing effects of 5,7-DHT lesions to the core and shell of the nucleus accumbens on the processing of irrelevant stimuli.

Marked variation in newborn resuscitation practice: a national survey in the UK (2012)
Journal Article
Mann, C., Ward, C., Grubb, M., Hayes-Gill, B., Crowe, J., Marlow, N., & Sharkey, D. (2012). Marked variation in newborn resuscitation practice: a national survey in the UK. Resuscitation, 83(5), https://doi.org/10.1016/j.resuscitation.2012.01.002

Abstract Background Although international newborn resuscitation guidance has been in force for some time, there are no UK data on current newborn resuscitation practices. Objective Establish delivery room (DR) resuscitation practices in the UK... Read More about Marked variation in newborn resuscitation practice: a national survey in the UK.

Risk, wealth and agrarian change in India: household-level hazards vs. late-modern global risks at different points along the risk transition (2012)
Journal Article
Jewitt, S., & Baker, K. (2012). Risk, wealth and agrarian change in India: household-level hazards vs. late-modern global risks at different points along the risk transition. Global Environmental Change, 22(2), https://doi.org/10.1016/j.gloenvcha.2011.11.010

The global poor often prioritise immediate hazards of food insecurity over temporally more distant risks like global warming. Yet the influence of socio-economic factors, temporal and spatial distance on risk perception remains under-researched. Data... Read More about Risk, wealth and agrarian change in India: household-level hazards vs. late-modern global risks at different points along the risk transition.

Reconstituting typeset Marriage Registers using simple software tools (2012)
Journal Article
Brailsford, D. F. (2012). Reconstituting typeset Marriage Registers using simple software tools. Computer Science - Research and Development, 27(2), https://doi.org/10.1007/s00450-010-0145-x

In a world of fully integrated software applications, which can seem daunting to develop and to maintain, it is sometimes useful to recall that a system of loosely-linked software components can provide surprisingly powerful and flexible methods for... Read More about Reconstituting typeset Marriage Registers using simple software tools.

Double checking the administration of medicines: what is the evidence? A systematic review (2012)
Journal Article
Alsulami, Z., Conroy, S., & Choonara, I. (2012). Double checking the administration of medicines: what is the evidence? A systematic review. Archives of Disease in Childhood, 97(9), https://doi.org/10.1136/archdischild-2011-301093

Objective To evaluate the evidence for double checking the administration of medicines. Design A systematic search of six electronic databases—Embase, Medline, British Nursing Index and Archive, CINAHL, National electronic library for Medicines (N... Read More about Double checking the administration of medicines: what is the evidence? A systematic review.

Localization of Hemodynamic Responses to Simple Visual Stimulation: An fNIRS Study (2012)
Journal Article
Wijeakumar, S., Shahani, U., Simpson, W. A., & McCulloch, D. L. (2012). Localization of Hemodynamic Responses to Simple Visual Stimulation: An fNIRS Study. Investigative Ophthalmology & Visual Science, 53(4), 2266-2273. https://doi.org/10.1167/iovs.11-8680

Purpose.: The purpose of the study was to use functional near-infrared spectroscopy (fNIRS) to explore the extent of activation in occipito-parietal cortices to high-contrast checkerboard stimuli. The distributions of oxyhemoglobin (HbO), deoxyhemogl... Read More about Localization of Hemodynamic Responses to Simple Visual Stimulation: An fNIRS Study.

The proline rich homeodomain protein PRH/Hhex forms stable oligomers that are highly resistant to denaturation (2012)
Journal Article
Shukla, A., Burton, N. M., Jayaraman, P., & Gaston, K. (2012). The proline rich homeodomain protein PRH/Hhex forms stable oligomers that are highly resistant to denaturation. PLoS ONE, 7(4), Article e35984. https://doi.org/10.1371/journal.pone.0035984

Background: Many transcription factors control gene expression by binding to specific DNA sequences at or near the genes that they regulate. However, some transcription factors play more global roles in the control of gene expression by altering the... Read More about The proline rich homeodomain protein PRH/Hhex forms stable oligomers that are highly resistant to denaturation.