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The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors (2011)
Journal Article
Valant, C., Lane, J. R., Sexton, P. M., & Christopoulos, A. (2012). The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors. Annual Review of Pharmacology and Toxicology, 52, 153-178. https://doi.org/10.1146/annurev-pharmtox-010611-134514

It is now acknowledged that G protein-coupled receptors, the largest class of drug targets, adopt multiple active states that can be preferentially stabilized by orthosteric ligands or allosteric modulators, thus giving rise to the phenomenon of path... Read More about The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors.

The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth (2011)
Journal Article
Chang, C.-Y., Hobley, L., Till, R., Capeness, M., Kanna, M., Burtt, W., …Sockett, R. E. (2011). The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth. Microbiology, 157(11), https://doi.org/10.1099/mic.0.052449-0

Bdellovibrio bacteriovorus grows in one of two ways: either (i) predatorily [in a host-dependent (HD) manner], when it invades the periplasm of another Gram-negative bacterium, exporting into the prey co-ordinated waves of soluble enzymes using the p... Read More about The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth.

Towards an understanding of neuroscience for science educators (2011)
Journal Article
Oliver, M. (2011). Towards an understanding of neuroscience for science educators. Studies in Science Education, 47(2), https://doi.org/10.1080/03057267.2011.604478

Advances in neuroscience have brought new insights to the development of cognitive functions. These data are of considerable interest to educators concerned with how students learn. This review documents some of the recent findings in neuroscience, w... Read More about Towards an understanding of neuroscience for science educators.

Rapid analysis of formic acid, acetic acid, and furfural in pretreated wheat straw hydrolysates and ethanol in a bioethanol fermentation using atmospheric pressure chemical ionisation mass spectrometry (2011)
Journal Article

Atmospheric pressure chemical ionisation mass spectrometry (APCI-MS) offers advantages as a rapid analytical technique for the quantification of three biomass degradation products (acetic acid, formic acid and furfural) within pretreated wheat straw... Read More about Rapid analysis of formic acid, acetic acid, and furfural in pretreated wheat straw hydrolysates and ethanol in a bioethanol fermentation using atmospheric pressure chemical ionisation mass spectrometry.

A clozapine-like effect of cyproheptadine on progressive ratio schedule performance (2011)
Journal Article
Olarte-Sánchez, C., Valencia Torres, L., Cassaday, H. J., Body, S., Bradshaw, C., Szabadi, E., & Goudie, A. (2012). A clozapine-like effect of cyproheptadine on progressive ratio schedule performance. Journal of Psychopharmacology, 26(6), 857-870. https://doi.org/10.1177/0269881111408961

The atypical antipsychotic drug clozapine has multiple pharmacological actions, some of which, including 5-hydroxytryptamine (5-HT2) and histamine (H1) receptor antagonist effects, are shared by the non-selective 5-HT receptor antagonist cyproheptadi... Read More about A clozapine-like effect of cyproheptadine on progressive ratio schedule performance.

‘Do as I say, but not as I do’: are next generation nurses role models for health? (2011)
Journal Article
Blake, H., Malik, S., Mo, P. K. H., & Pisano, C. (2011). ‘Do as I say, but not as I do’: are next generation nurses role models for health?. Perspectives in Public Health, 131(5), 231-239. https://doi.org/10.1177/1757913911402547

Aim: Promoting healthy lifestyles plays a key role in professional nursing yet nurses do not always practice what they preach. Efforts are currently being made to improve the health of NHS staff, yet little is known about the health and lifestyle beh... Read More about ‘Do as I say, but not as I do’: are next generation nurses role models for health?.

Reflowable documents composed from pre-rendered atomic components (2011)
Presentation / Conference Contribution
Pinkney, A. J., Bagley, S. R., & Brailsford, D. F. (2011). Reflowable documents composed from pre-rendered atomic components.

Mobile eBook readers are now commonplace in today’s society, but their document layout algorithms remain basic, largely due to constraints imposed by short battery life. At present, with any eBook file format not based on PDF, the layout of the docum... Read More about Reflowable documents composed from pre-rendered atomic components.

Automated conversion of Web-based marriage register data into a printed format with predefined layout (2011)
Presentation / Conference Contribution
Brailsford, D. F. (2011). Automated conversion of Web-based marriage register data into a printed format with predefined layout.

The Phillimore Marriage Registers for England were published in the period 1896 to 1922 and have defined a standard layout format for the typesetting of marriage data. However, not all English parish churches had their marriage registers analysed and... Read More about Automated conversion of Web-based marriage register data into a printed format with predefined layout.

Functional network construction in Arabidopsis using rule-based machine learning on large-scale data sets (2011)
Journal Article
Bassel, G. W., Glaab, E., Marquez, J., Holdsworth, M. J., & Barcardit, J. (2011). Functional network construction in Arabidopsis using rule-based machine learning on large-scale data sets. Plant Cell, 23(9), https://doi.org/10.1105/tpc.111.088153

The meta-analysis of large-scale postgenomics data sets within public databases promises to provide important novel biological knowledge. Statistical approaches including correlation analyses in coexpression studies of gene expression have emerged as... Read More about Functional network construction in Arabidopsis using rule-based machine learning on large-scale data sets.

Sun safety measures among construction workers in Britain (2011)
Journal Article
Madgwick, P., Houdmont, J., & Randall, R. (2011). Sun safety measures among construction workers in Britain. Occupational Medicine, 61(6), https://doi.org/10.1093/occmed/kqr054

Background: Relative to other occupational groups in Britain, construction workers have a high incidence of skin cancer attributable to sun exposure. The importance of sun safety measures to minimize the risk of skin cancer is recognized in the liter... Read More about Sun safety measures among construction workers in Britain.

Delayed publications of clinical trials in cystic fibrosis (2011)
Journal Article
Hurley, M., Prayle, A., & Smyth, A. R. (2011). Delayed publications of clinical trials in cystic fibrosis. Journal of Cystic Fibrosis, 11(1), https://doi.org/10.1016/j.jcf.2011.08.004

Background: When the publication of important trial data is delayed, or data are never published, this will prevent the proper practice of evidence based medicine through robust systematic reviews. Clinical trial registries allow researchers to... Read More about Delayed publications of clinical trials in cystic fibrosis.

Quiet in class: classification, noise and the dendritic cell algorithm (2011)
Journal Article
Gu, F., Feyereisl, J., Oates, R., Reps, J., Greensmith, J., & Aickelin, U. (2011). Quiet in class: classification, noise and the dendritic cell algorithm. Lecture Notes in Artificial Intelligence, 6825, https://doi.org/10.1007/978-3-642-22371-6_17

Theoretical analyses of the Dendritic Cell Algorithm (DCA) have yielded several criticisms about its underlying structure and operation. As a result, several alterations and fixes have been suggested in the literature to correct for these findings. A... Read More about Quiet in class: classification, noise and the dendritic cell algorithm.