All Outputs (228)

P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors (2007)
Journal Article

Objective P-glycoprotein (pgp) is a membrane transporter encoded by the multidrug resistance (MDR1, ABCB1) gene. Pgp is a poor prognostic factor in elderly patients with acute myeloid leukemia (AML). In addition to its role in drug efflux, pgp has b... Read More about P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors.

SNPping away at the pathogenesis of Crohn's disease (2007)
Journal Article

Characterization of theBMPR25?-Untranslated Region and a Novel Mutation in Pulmonary Hypertension (2007)
Journal Article

Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus (2007)
Journal Article

One way to dissect the antibody response to an invading microorganism is to clone the antibody repertoire from immune donors and subsequently characterize the specific antibodies. Recently, methodological advances have allowed investigations of neutr... Read More about Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus.

Asynchronous cooperative local search for the office-space-allocation problem (2007)
Journal Article

We investigate cooperative local search to improve upon known results of the office-space-allocation problem in universities and other organizations. A number of entities (e.g., research students, staff, etc.) must be allocated into a set of rooms so... Read More about Asynchronous cooperative local search for the office-space-allocation problem.

Flexural Behavior of Brittle RC Members Rehabilitated with Concrete Jacketing (2007)
Journal Article

The composite flexural action of prismatic reinforced concrete (RC) members repaired/strengthened by RC jacketing was modeled with a dual-section approach. The model considers the relative slip at the interface between the existing member and the jac... Read More about Flexural Behavior of Brittle RC Members Rehabilitated with Concrete Jacketing.

O! She doth teach the torches to burn bright: How JULIET can help authors and repository advocates. (2007)
Journal Article

JULIET is a service provided by SHERPA. Its mission is to provide a brief summary of each funding agency’s policy on self-archiving of the published research they have funded. Each entry covers the requirements and details: -Whether archiving is man... Read More about O! She doth teach the torches to burn bright: How JULIET can help authors and repository advocates..

Turkey, the EU and social policy (2007)
Journal Article

DRIVER: Building the Network for Accessing Digital Repositories across Europe (2007)
Journal Article

Relationships between tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mRNAs and toxicity in the developing male Wistar(Han) rat (2007)
Journal Article

We compared the effects of a single acute dose, or chronic fetal exposure, to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the male reproductive system of the Wistar(Han) rat. Tissue samples were taken from dams on GD16 and GD21, and from offspring... Read More about Relationships between tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mRNAs and toxicity in the developing male Wistar(Han) rat.

Should data monitoring committees assess efficacy when considering safety in trails in acute stroke? (2007)
Journal Article

The primary role of a trials Data Monitoring Committee (DMC) is to ensure the safety of enrolled patients. In stroke trials, safety is monitored typically by comparing death and stroke specific events between treatment groups. DMCs may also have the... Read More about Should data monitoring committees assess efficacy when considering safety in trails in acute stroke?.

Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep (2007)
Journal Article

The liver is an important metabolic and endocrine organ in the fetus but the extent to which its hormone receptor (R) sensitivity is developmentally regulated in early life is not fully established. We, therefore, examined developmental changes in mR... Read More about Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep.

Previewing distracters reduces their effective contrast (2007)
Journal Article

In a visual search task, when half the distracters are presented earlier than the remainder (‘previewed’), observers find the target item more efficiently than when all the items are presented together—the preview benefit. We measured psychometric fu... Read More about Previewing distracters reduces their effective contrast.

Multiple sclerosis findings in the spinal cord (2007)
Journal Article

Modelling and Animation of Brittle Fracture in Three Dimensions (2007)
Thesis

This thesis describes a system for simulating fracture in brittle objects. The system combines rigid body simulation methods with a constraint-based model to animate fracturing of arbitrary polyhedral shaped objects under impact. The objects are repr... Read More about Modelling and Animation of Brittle Fracture in Three Dimensions.

Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST) (2007)
Journal Article

Introduction: Female sex is predictive of poor functional outcome in stroke, even after correction for prognostic factors. Poor quality of life (QoL) is observed in stroke survivors, with lower scores seen in the most disabled patients. We used data... Read More about Sex differences in quality of life in stroke survivors. Data from the Tinzaparin in Acute Ischaemic Stroke Trial (TAIST).

Extraction and characterization of oil bodies from soy beans: A natural source of pre-emulsified soybean oil (2007)
Journal Article

Soybeans contain oil bodies that are coated by a layer of oleosin proteins. In nature, this protein coating protects the oil bodies from environmental stresses and may be utilized by food manufacturers for the same purpose. In this study, oil bodies... Read More about Extraction and characterization of oil bodies from soy beans: A natural source of pre-emulsified soybean oil.

Values of L-functions at integers outside the critical strip (2007)
Journal Article

International Factors and the 1964 Election (2007)
Journal Article

International issues are not usually seen as having been significant to the 1964 general election result. Harold Wilson made only limited references to foreign policy and defence during the campaign, while opinion polls showed that voters saw domesti... Read More about International Factors and the 1964 Election.

Understanding Retail Productivity by Simulating Management Practices (2007)
Conference Proceeding

Intelligent agents offer a new and exciting way of understanding the world of work. In this paper we apply agent-based modeling and simulation to investigate a set of problems in a retail context. Specifically, we are working to understand the relati... Read More about Understanding Retail Productivity by Simulating Management Practices.