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In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents (2007)
Journal Article
Stepek, G., Lowe, A. E., Buttle, D. J., Duce, I. R., & Behnke, J. M. (2007). In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents. Journal of Helminthology, 81(4), https://doi.org/10.1017/S0022149X0786408X

Infections with gastrointestinal (GI) nematodes are amongst the most prevalent worldwide, especially in tropical climates. Control of these infections is primarily through treatment with anthelmintic drugs, but the rapid development of resistance to... Read More about In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents.

The anthelmintic efficacy of plant-derived cysteine proteinases against the rodent gastrointestinal nematode, Heligmosomoides polygyrus, in vivo (2007)
Journal Article
Stepek, G., Lowe, A., Buttle, D. J., Duce, I., & Behnke, J. M. (2007). The anthelmintic efficacy of plant-derived cysteine proteinases against the rodent gastrointestinal nematode, Heligmosomoides polygyrus, in vivo. Parasitology, 134(10), https://doi.org/10.1017/S0031182007002867

Gastrointestinal (GI) nematodes are important disease-causing organisms, controlled primarily through treatment with synthetic drugs, but the efficacy of these drugs has declined due to widespread resistance, and hence new drugs, with different modes... Read More about The anthelmintic efficacy of plant-derived cysteine proteinases against the rodent gastrointestinal nematode, Heligmosomoides polygyrus, in vivo.

Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo (2007)
Journal Article
Stepek, G., Lowe, A., Buttle, D. J., Duce, I., & Behnke, J. M. (2007). Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo. Parasitology, 134(1), https://doi.org/10.1017/S0031182006001302

Cysteine proteinases from the fruit and latex of plants, including papaya, pineapple and fig, were previously shown to have a rapid detrimental effect, in vitro, against the rodent gastrointestinal nematodes, Heligmosomoides polygyrus (which is found... Read More about Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo.

Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes (2007)
Journal Article
Stepek, G., Curtis, R., Kerry, B., Shewry, P., Clark, S., Lowe, A., …Behnke, J. (2007). Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes. Parasitology, 134(12), https://doi.org/10.1017/S0031182007003289

Cysteine proteinases from the fruit and latex of plants, such as papaya, pineapple and fig, have previously been shown to have substantial anthelmintic efficacy, in vitro and in vivo, against a range of animal parasitic nematodes. In this paper, we d... Read More about Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes.