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Peripheral INSL3 concentrations decline with age in a large population of Australian men (2006)
Journal Article
Anand-Ivell, R., Wohlgemuth, J., Haren, M. T., Hope, P. J., Hatzinikolas, G., Wittert, G., & Ivell, R. (2006). Peripheral INSL3 concentrations decline with age in a large population of Australian men. International Journal of Andrology, 29(6), 618-626. https://doi.org/10.1111/j.1365-2605.2006.00714.x

The novel peptide hormone insulin-like peptide 3 (INSL3) is a major secretory product of the Leydig cells of the testis, and in adult men is secreted into the blood, giving rise to circulating concentrations ranging from 0.5 to 2.5 ng/mL. We studied... Read More about Peripheral INSL3 concentrations decline with age in a large population of Australian men.

Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis (2006)
Journal Article
Anand-Ivell, R. J., Relan, V., Balvers, M., Coiffec-Dorval, I., Fritsch, M., Bathgate, R. A., & Ivell, R. (2006). Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis. Biology of Reproduction, 74(5), 945-953. https://doi.org/10.1095/biolreprod.105.048165

The new peptide hormone insulin-like peptide 3 (INSL3) is a member of the insulin-relaxin family, yet, unlike insulin, it signals through a new G-protein coupled receptor, LGR8, distantly related to the receptors for LH and FSH. INSL3 is produced in... Read More about Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis.