All Outputs (146)

Report on BCTCS 2005 (2005)
Journal Article

This report contains edited abstracts from BCTCS 2005, which was held on 22nd to 24th March 2005 in Nottingham, England.

Insulin-like factor 3: Where are we now? (2005)
Journal Article

Insulin-like factor 3 (INSL3), previously known as the relaxin-like factor (RLF), is a major peptide hormone secreted from the testicular Leydig cells of adult men and circulating in the blood at a concentration of approximately 1 ng/mL. Women also p... Read More about Insulin-like factor 3: Where are we now?.

A high fidelity tissue-based cardiac surgical simulator (2005)
Journal Article

Issues concerning the training and certification of surgical specialists have taken on great significance in the last decade. A realistic computer-assisted, tissue-based simulator developed for use in the training of cardiac surgical residents in the... Read More about A high fidelity tissue-based cardiac surgical simulator.

Discovery of antagonist peptides against bacterial helicase-primase interaction in B. stearothermophilus by reverse yeast three-hybrid (2005)
Journal Article

Developing small-molecule antagonists against protein-protein interactions will provide powerful tools for mechanistic/functional studies and the discovery of new antibacterials. We have developed a reverse yeast three-hybrid approach that allows hig... Read More about Discovery of antagonist peptides against bacterial helicase-primase interaction in B. stearothermophilus by reverse yeast three-hybrid.

Voices in the Silence: Narratives of disadvantage, social context, and school mathematics in post-apartheid South Africa (2005)
Thesis

"Voices in the Silence" is a critical exploration of the construction of disadvantage in school mathematics in social context. It provides a reflexive, narrative account of a pedagogic journey towards understanding the pedagogizing of difference in m... Read More about Voices in the Silence: Narratives of disadvantage, social context, and school mathematics in post-apartheid South Africa.

Voices in the Silence: Narratives of disadvantage, social context, and school mathematics in post-apartheid South Africa (PhD thesis) (2005)
Thesis

Spatially Distinct Cl– Influx and Efflux Pathways Interact to Maintain Lens Volume and Transparency (2005)
Journal Article

Modulation of pRb/E2F functions in the regulation of cell cycle and in cancer (2005)
Journal Article

Cell proliferation is regulated by the cell cycle, and in order to divide the cell must enter a mitotic state. Prior to mitosis the cell is required to pass through a number of checkpoints, including the critical G1/S restriction point governed by th... Read More about Modulation of pRb/E2F functions in the regulation of cell cycle and in cancer.

Mode locking in a periodically forced "ghostbursting" neuron model (2005)
Journal Article

We study a minimal integrate-and-fire based model of a " ghostbursting" neuron under periodic stimulation. These neurons are involved in sensory processing in weakly electric fish. There exist regions in parameter space in which the model neuron is m... Read More about Mode locking in a periodically forced "ghostbursting" neuron model.

Introducing the National Library for Health Skin Conditions Specialist Library (2005)
Journal Article

Background: This paper introduces the new National Library for Health Skin Conditions Specialist Library http://www.library.nhs.uk/skin. Description: The aims, scope and audience of the new NLH Skin Conditions Specialist Library, and the compositi... Read More about Introducing the National Library for Health Skin Conditions Specialist Library.

Bumps, breathers, and waves in a neural network with spike frequency adaptation (2005)
Journal Article

In this Letter we introduce a continuum model of neural tissue that include the effects of so-called spike frequency adaptation (SFA). The basic model is an integral equation for synaptic activity that depends upon the non-local network connectivity... Read More about Bumps, breathers, and waves in a neural network with spike frequency adaptation.

Proof Methods for Corecursive Programs (2005)
Journal Article

Recursion is a well-known and powerful programming technique, with a wide variety of applications. The dual technique of corecursion is less well-known, but is increasingly proving to be just as useful. This article is a tutorial on the four main m... Read More about Proof Methods for Corecursive Programs.

Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of haemophilus influenzae and its role in bacterial resistance to complement-mediated killing (2005)
Journal Article

The phase-variable locus lex2 is required for expression of a Haemophilus influenzae lipopolysaccharide (LPS) epitope of previously unknown structure. This epitope, which is reactive with monoclonal antibody (MAb) 5G8, has been associated with virule... Read More about Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of haemophilus influenzae and its role in bacterial resistance to complement-mediated killing.

Constraints on the metagalactic hydrogen ionization rate from the Lyman-alpha forest opacity (2005)
Journal Article

Waiting times for radiotherapy: Variation over time and between cancer networks in southeast England (2005)
Journal Article

The aim of this study was to investigate variations in the length of time that patients with cancer wait from diagnosis to treatment with radiotherapy. A total of 57426 men and 71018 women diagnosed with cancer between 1992 and 2001 and receiving rad... Read More about Waiting times for radiotherapy: Variation over time and between cancer networks in southeast England.

Identification of perennial ryegrass (Lolium perenne (L.)) and meadow fescue (Festuca pratensis (Huds.)) candidate orthologous sequences to the rice Hd1(Se1) and barley HvCO1 CONSTANS-like genes through comparative mapping and microsynteny (2005)
Journal Article

Microsynteny with rice and comparative genetic mapping were used to identify candidate orthologous sequences to the rice Hd1(Se1) gene in Lolium perenne and Festuca pratensis. A F. pratensis bacterial artificial chromosome (BAC) library was screened... Read More about Identification of perennial ryegrass (Lolium perenne (L.)) and meadow fescue (Festuca pratensis (Huds.)) candidate orthologous sequences to the rice Hd1(Se1) and barley HvCO1 CONSTANS-like genes through comparative mapping and microsynteny.

The Lyman-alpha forest opacity and the metagalactic hydrogen ionization rate at z~2-4 (2005)
Journal Article

Estimates of the metagalactic hydrogen ionization rate from the Lyman-alpha forest opacity in QSO absorption spectra depend on the complex density distribution of neutral hydrogen along the line-of-sight. We use a large suite of high resolution hydro... Read More about The Lyman-alpha forest opacity and the metagalactic hydrogen ionization rate at z~2-4.

A study to investigate the extent of delivery of an intervention in asthma, in a UK national community pharmacy chain, using mystery customers (2005)
Journal Article

Objective: The objective of this study was to implement a brief intervention in asthma within a UK national pharmacy chain, and through the use of mystery customers, measure the extent of delivery of the intervention over a 4-month period. Methods: M... Read More about A study to investigate the extent of delivery of an intervention in asthma, in a UK national community pharmacy chain, using mystery customers.

A spectrophotometric assay for fatty acid amide hydrolase suitable for high-throughput screening (2005)
Journal Article

Signalling via the endocannabinoids anandamide and 2-arachidonylglycerol appears to be terminated largely through the action of the enzyme fatty acid amide hydrolase (FAAH). In this report, we describe a simple spectrophotometric assay to detect FAAH... Read More about A spectrophotometric assay for fatty acid amide hydrolase suitable for high-throughput screening.

Expected, sensed, and desired: A framework for designing sensing-based interaction (2005)
Journal Article

Movements of interfaces can be analyzed in terms of whether they are expected, sensed, and desired. Expected movements are those that users naturally perform; sensed are those that can be measured by a computer; and desired movements are those that a... Read More about Expected, sensed, and desired: A framework for designing sensing-based interaction.