All Outputs (214)

Commercial Law Intersections (2020)
Working Paper

Commercial law is not a single, monolithic entity. It has grown into a dense thicket of subject-specific branches that govern a broad range of transactions and corporate actions. When one of such dealings or activities falls concurrently within the p... Read More about Commercial Law Intersections.

Improving the Involvement of People with Dementia in Developing Technology–Based Interventions: a Narrative Synthesis Review and Best Practice Guidelines (Preprint) (2020)
Working Paper

Background: Technology can be helpful in supporting people with dementia in their daily lives. However, people with dementia are often not fully involved in the development process of new technology. This lack of involvement of people with dementia... Read More about Improving the Involvement of People with Dementia in Developing Technology–Based Interventions: a Narrative Synthesis Review and Best Practice Guidelines (Preprint).

The Iso2k Database: A global compilation of paleo-δ18O and δ2H records to aid understanding of Common Era climate (2020)
Working Paper

Reconstructions of global hydroclimate during the Common Era (CE; the past ~ 2000 years) are important for providing context for current and future global environmental change. Stable isotope ratios in water are quantitative indicators of hydroclimat... Read More about The Iso2k Database: A global compilation of paleo-δ18O and δ2H records to aid understanding of Common Era climate.

The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2020)
Working Paper

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterised by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.

Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention (2020)
Working Paper

Background: Sedentary behavior (SB) is associated with various adverse health outcomes. The prevalence of prolonged sitting at work among office workers makes a case for SB interventions to target this setting and population. Everyday mundane obje... Read More about Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention.

Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention (2020)
Working Paper

Background: Sedentary behavior (SB) is associated with various adverse health outcomes. The prevalence of prolonged sitting at work among office workers makes a case for SB interventions to target this setting and population. Everyday mundane obje... Read More about Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention.

Policy Effects of International Taxation on Firm Dynamics and Capital Structure (2020)
Working Paper

This paper develops a quantitative open economy framework with dynamics, firm heterogeneity and financial frictions to study the impact of corporate tax reforms targeted at multinationals. The model quantifies their impact on productivity, GDP and we... Read More about Policy Effects of International Taxation on Firm Dynamics and Capital Structure.

Genetic analysis of the Arabidopsis TIR1/AFB auxin receptors reveals both overlapping and specialized functions (2019)
Working Paper

The impact of algorithmic decision-making processes on young people’s well-being (Preprint) (2019)
Working Paper

Background: Algorithms rule the online environments and are essential for performing data processing, filtering, personalisation and other tasks. Research has shown that children and young people make up a significant proportion of Internet users, h... Read More about The impact of algorithmic decision-making processes on young people’s well-being (Preprint).

Development of bioactive electrospun scaffolds suitable to support skin fibroblasts and release Lucilia sericata maggot excretion/secretion (2019)
Working Paper

Larval therapy has been reported to exert beneficial actions upon chronic wound healing by promoting granulation tissue formation, antimicrobial activity and degrading necrotic tissue. However, the use of live maggots is problematic for patient accep... Read More about Development of bioactive electrospun scaffolds suitable to support skin fibroblasts and release Lucilia sericata maggot excretion/secretion.

Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes (2019)
Working Paper

The accessory genes of prokaryote and eukaryote pangenomes accumulate by horizontal gene transfer, differential gene loss, and the effects of selection and drift. We have developed Coinfinder, a software program that assesses whether sets of homologo... Read More about Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes.

A randomised controlled trial to assess the effectiveness and cost-effectiveness of tailored web- and text-based smoking cessation support in primary care: iQuit in Practice II trial protocol (2019)
Working Paper

An exploration of the experiences of professionals supporting patients approaching the end of life in medicines management at home. A qualitative study. An exploration of the experiences of professionals supporting patients approaching the end of life in medicines management at home. A qualitative study. (2019)
Working Paper

Background: The management of medicines towards the end of life can place increasing burdens and responsibilities on patients and families. This has received little attention yet it can be a source of great difficulty and distress patients and famili... Read More about An exploration of the experiences of professionals supporting patients approaching the end of life in medicines management at home. A qualitative study. An exploration of the experiences of professionals supporting patients approaching the end of life in medicines management at home. A qualitative study..

ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies (2019)
Working Paper

Arterial spin labeling (ASL) has undergone significant development since its inception, with a focus on improving standardization and reproducibility of its acquisition and quantification. In a community-wide effort towards robust and reproducible cl... Read More about ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies.

Thioredoxin system protein expression in carcinomas of the pancreas, bile duct and ampulla (2019)
Working Paper

Background: Pancreatic cancer (PC), including the ampulla and bile duct, is very aggressive, and thus difficult to treat with effective therapies. The current treatment options have failed to improve PC five-year survival rates over the last 30 to 40... Read More about Thioredoxin system protein expression in carcinomas of the pancreas, bile duct and ampulla.

Right to an Explanation Considered Harmful (2019)
Working Paper

Protocol for the development of an evidence-based ‘Best Practice Model’ for Teams Managing Crisis in Dementia (2019)
Working Paper

Background: Teams working in the community to manage crisis in dementia are available, but with widely varying models of practice it is difficult to determine the effectiveness of such teams. The aim of this study is to develop a model of best pra... Read More about Protocol for the development of an evidence-based ‘Best Practice Model’ for Teams Managing Crisis in Dementia.

Civil service management in Bangladesh: evidence from a survey of more than 1,000 civil servants (2019)
Working Paper

Agent-Based Simulation Modelling for Reflecting on Consequences of Digital Mental Health (2019)
Working Paper

The premise of this working paper is based around agent-based simulation models and how to go about creating them from given incomplete information. Agent-based simulations are stochastic simulations that revolve around groups of agents that each hav... Read More about Agent-Based Simulation Modelling for Reflecting on Consequences of Digital Mental Health.

Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche (2018)
Working Paper

Stem cells within epithelial tissues reside in anatomical structures known as crypts that are known to contribute to the mechanical and chemical milieu important for function. To date, epithelial stem cell therapies have largely ignored the niche and... Read More about Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche.