All Outputs (214)

Review of Networking and Tangible Security Techniques for Domestic IoT Devices and Initial Ideas (2020)
Working Paper

The number of connected devices including Internet of Things (IoTs) on the Internet is growing fast. According to recent Gartner research, the estimated number of IoT devices is 5.8 billion in 2020 (Gartner, 2019). The countries that are leading the... Read More about Review of Networking and Tangible Security Techniques for Domestic IoT Devices and Initial Ideas.

Assessing the impact of physicochemical parameters in the predictive capabilities of thermodynamics-based stoichiometric approaches under mesophilic and thermophilic conditions (2020)
Working Paper

Metabolic engineering in the post-genomic era is characterised by the development of new methods for metabolomics and fluxomics, supported by the integration of genetic engineering tools and mathematical modelling. Particularly, constraint-based stoi... Read More about Assessing the impact of physicochemical parameters in the predictive capabilities of thermodynamics-based stoichiometric approaches under mesophilic and thermophilic conditions.

Near Fibre Electromyography (2020)
Working Paper

Near fibre electromyography (NFEMG) is the use of specifically high-pass filtered motor unit potential (MUPs) (i.e. near fibre MUPs (NFMs)) extracted from needle-detected EMG signals for the examination of changes in motor unit (MU) morphology and el... Read More about Near Fibre Electromyography.

An Individual Cognitive Stimulation Therapy App for People With Dementia and Their Carers: Protocol for a Feasibility Randomized Controlled Trial (2020)
Working Paper

Background: There is a need for more resources to support the cognition and quality of life (QoL) of people with dementia. The individual Cognitive Stimulation Therapy application (iCST app) aims to provide cognitive stimulation and social interacti... Read More about An Individual Cognitive Stimulation Therapy App for People With Dementia and Their Carers: Protocol for a Feasibility Randomized Controlled Trial.

The role of school leaders in reform (2020)
Working Paper

School leaders sit at the fulcrum of educational reform initiatives. This is particularly the case in decentralised school systems in which schools have relatively high levels of autonomy, or decision-making rights, in relation to operational and ins... Read More about The role of school leaders in reform.

Developing a model of best practice for teams managing crisis in people with dementia: A consensus approach (2020)
Working Paper

Background: Teams delivering crisis resolution services for people with dementia and their carers provide short-term interventions to prevent admission to acute care settings. There is great variation in these services across the UK. This article rep... Read More about Developing a model of best practice for teams managing crisis in people with dementia: A consensus approach.

Arabidopsis thaliana zinc accumulation in leaf trichomes is correlated with zinc concentration in leaves (2020)
Working Paper

Zinc (Zn) is a key micronutrient. In humans, Zn deficiency is a common nutritional disorder, and most people acquire dietary Zn from eating plants. In plants, Zn deficiency can decrease plant growth and yield. Understanding Zn homeostasis in plants c... Read More about Arabidopsis thaliana zinc accumulation in leaf trichomes is correlated with zinc concentration in leaves.

WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry (2020)
Working Paper

Interprofessional learning (IPL) is essential to prepare healthcare trainees as the future public health workforce. WHIRL was an innovative IPL intervention that engaged multi-professional teams of volunteer healthcare trainees (n=20) to deliver heal... Read More about WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry.

Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study (2020)
Working Paper

Objective To characterise the clinical features of children and young people admitted to hospital with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the UK, and explore factors associated with admissio... Read More about Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study.

Inkjet based 3D Printing of bespoke medical devices that resist bacterial biofilm formation (2020)
Working Paper

We demonstrate the formulation of advanced functional 3D printing inks that prevent the formation of bacterial biofilms in vivo. Starting from polymer libraries, we show that a biofilm resistant object can be 3D printed with the potential for shape a... Read More about Inkjet based 3D Printing of bespoke medical devices that resist bacterial biofilm formation.

Health Care Cybersecurity Challenges and Solutions Under the Climate of COVID-19: Scoping Review (2020)
Working Paper

Background: Coronavirus disease (COVID-19) has been an unprecedented challenge to the global health care system. It has further challenged the resilience of the healthcare information system (HIS), which has affected the ability to achieve the glo... Read More about Health Care Cybersecurity Challenges and Solutions Under the Climate of COVID-19: Scoping Review.

Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report (2020)
Working Paper

Background Coronavirus disease 2019 (COVID-19) is associated with diffuse lung damage. Corticosteroids may modulate immune-mediated lung injury and reducing progression to respiratory failure and death. Methods The Randomised Evaluation of COVID-1... Read More about Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report.

Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors (2020)
Working Paper

Suberin is a hydrophobic biopolymer that can be deposited at the periphery of cells, forming protective barriers against biotic and abiotic stress. In roots, suberin forms lamellae at the periphery of endodermal cells where it plays crucial roles in... Read More about Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors.

Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time (2020)
Working Paper

Stochastic optical reconstruction microscopy (STORM) is one of the most commonly used super-resolution microscopy techniques. Popular implementations of STORM utilize aromatic fluorophores and consist of a number of intrinsic limitations such the fin... Read More about Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time.

Microrheology reveals microscale viscosity gradients in planktonic systems (2020)
Working Paper

Microbial activity in planktonic systems creates a dynamic and heterogeneous microscale seascape that harbours a diverse community of microorganisms and ecological interactions of global significance. In recent decades a great effort has been put int... Read More about Microrheology reveals microscale viscosity gradients in planktonic systems.

The spatial percept of tinnitus is associated with hearing asymmetry: subgroup comparisons (2020)
Working Paper

The spatial percept of tinnitus is hypothesized as an important variable for tinnitus subtyping. Hearing asymmetry often associates with tinnitus laterality, but not always. One of the methodological limitations for cross-study comparisons is how the... Read More about The spatial percept of tinnitus is associated with hearing asymmetry: subgroup comparisons.

Unpacking the Allee effect: determining individual-level mechanisms that drive global population dynamics (2020)
Working Paper

We present a solid theoretical foundation for interpreting the origin of Allee effects by providing the missing link in understanding how local individual-based mechanisms translate to global population dynamics. Allee effects were originally propose... Read More about Unpacking the Allee effect: determining individual-level mechanisms that drive global population dynamics.

Inhibition of neuroinflammatory nitric oxide signalling supresses protein glycation and recovers neuronal dysfunction in prion disease (2020)
Working Paper

Background: Several neurodegenerative diseases associated with protein misfolding (Alzheimer’s, Parkinson’s disease) exhibit oxidative and nitrergic stress following initiation of neuroinflammatory pathways. Associated nitric oxide (NO)-mediated post... Read More about Inhibition of neuroinflammatory nitric oxide signalling supresses protein glycation and recovers neuronal dysfunction in prion disease.

A randomised controlled trial to assess the effectiveness and cost-effectiveness of tailored web- and text-based smoking cessation support in primary care: iQuit in Practice II trial protocol (Preprint) (2020)
Working Paper

Background: The prevalence of smoking is in decline, however, it continues to be a major public health burden. In England, primary care is the health setting that provides smoking cessation support to the most smokers. However, this setting has one o... Read More about A randomised controlled trial to assess the effectiveness and cost-effectiveness of tailored web- and text-based smoking cessation support in primary care: iQuit in Practice II trial protocol (Preprint).

A novel allele of ASY3 promotes meiotic stability in autotetraploid Arabidopsis lyrata (2020)
Working Paper

In this study we performed a genotype-phenotype association analysis of meiotic stability in ten autotetraploid Arabidopsis lyrata and A. lyrata/A. arenosa hybrid populations collected from the Wachau region and East Austrian Forealps. The aim was to... Read More about A novel allele of ASY3 promotes meiotic stability in autotetraploid Arabidopsis lyrata.