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All Outputs (41)

Arabidopsis thaliana zinc accumulation in leaf trichomes is correlated with zinc concentration in leaves (2020)
Working Paper

Zinc (Zn) is a key micronutrient. In humans, Zn deficiency is a common nutritional disorder, and most people acquire dietary Zn from eating plants. In plants, Zn deficiency can decrease plant growth and yield. Understanding Zn homeostasis in plants c... Read More about Arabidopsis thaliana zinc accumulation in leaf trichomes is correlated with zinc concentration in leaves.

Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study (2020)
Working Paper

Objective To characterise the clinical features of children and young people admitted to hospital with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the UK, and explore factors associated with admissio... Read More about Clinical characteristics of children and young people hospitalised with covid-19 in the United Kingdom: prospective multicentre observational cohort study.

Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors (2020)
Working Paper

Suberin is a hydrophobic biopolymer that can be deposited at the periphery of cells, forming protective barriers against biotic and abiotic stress. In roots, suberin forms lamellae at the periphery of endodermal cells where it plays crucial roles in... Read More about Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors.

Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time (2020)
Working Paper

Stochastic optical reconstruction microscopy (STORM) is one of the most commonly used super-resolution microscopy techniques. Popular implementations of STORM utilize aromatic fluorophores and consist of a number of intrinsic limitations such the fin... Read More about Self-activated photoblinking of nitrogen vacancy centers in nanodiamonds (sandSTORM): A method for rapid single molecule localization microscopy with unlimited observation time.

Unpacking the Allee effect: determining individual-level mechanisms that drive global population dynamics (2020)
Working Paper

We present a solid theoretical foundation for interpreting the origin of Allee effects by providing the missing link in understanding how local individual-based mechanisms translate to global population dynamics. Allee effects were originally propose... Read More about Unpacking the Allee effect: determining individual-level mechanisms that drive global population dynamics.

Inhibition of neuroinflammatory nitric oxide signalling supresses protein glycation and recovers neuronal dysfunction in prion disease (2020)
Working Paper

Background: Several neurodegenerative diseases associated with protein misfolding (Alzheimer’s, Parkinson’s disease) exhibit oxidative and nitrergic stress following initiation of neuroinflammatory pathways. Associated nitric oxide (NO)-mediated post... Read More about Inhibition of neuroinflammatory nitric oxide signalling supresses protein glycation and recovers neuronal dysfunction in prion disease.

Improving the Involvement of People with Dementia in Developing Technology–Based Interventions: a Narrative Synthesis Review and Best Practice Guidelines (Preprint) (2020)
Working Paper

Background: Technology can be helpful in supporting people with dementia in their daily lives. However, people with dementia are often not fully involved in the development process of new technology. This lack of involvement of people with dementia... Read More about Improving the Involvement of People with Dementia in Developing Technology–Based Interventions: a Narrative Synthesis Review and Best Practice Guidelines (Preprint).

The Iso2k Database: A global compilation of paleo-δ18O and δ2H records to aid understanding of Common Era climate (2020)
Working Paper

Reconstructions of global hydroclimate during the Common Era (CE; the past ~ 2000 years) are important for providing context for current and future global environmental change. Stable isotope ratios in water are quantitative indicators of hydroclimat... Read More about The Iso2k Database: A global compilation of paleo-δ18O and δ2H records to aid understanding of Common Era climate.

The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome (2020)
Working Paper

Tourette syndrome (TS) is a neurological disorder of childhood onset that is characterised by the occurrence of motor and vocal tics. TS is associated with cortical-striatal-thalamic-cortical circuit [CSTC] dysfunction and hyper-excitability of corti... Read More about The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome.

Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention (2020)
Working Paper

Background: Sedentary behavior (SB) is associated with various adverse health outcomes. The prevalence of prolonged sitting at work among office workers makes a case for SB interventions to target this setting and population. Everyday mundane obje... Read More about Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention.

Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention (2020)
Working Paper

Background: Sedentary behavior (SB) is associated with various adverse health outcomes. The prevalence of prolonged sitting at work among office workers makes a case for SB interventions to target this setting and population. Everyday mundane obje... Read More about Using digitally augmented objects to reduce sedentary behavior in office workers: design and development of the WorkMyWay intervention.