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All Outputs (39)

Selective Photocatalytic Reduction of CO2 to CH4 over NU-1000 Metal-Organic Frameworks (2024)
Preprint / Working Paper
Korhonen, P., Thangamuthu, M., Castaldelli, E., Diego-Lopez, A., Weilhard, A., Clowes, R., O'Shea, J., Laybourn, A., & Lanterna, A. Selective Photocatalytic Reduction of CO2 to CH4 over NU-1000 Metal-Organic Frameworks

CO2 adsorption and its subsequent utilization represent a promising avenue for mitigating climate change. The conver-sion of CO2 into valuable and useful products like carbon monoxide, methane, and methanol offers significant economic benefits. Howev... Read More about Selective Photocatalytic Reduction of CO2 to CH4 over NU-1000 Metal-Organic Frameworks.

Anchor Carbon Dots Inside Nh2-Mil-88b Via Ship-in-A-Bottle Strategy for Dual Signal Enhancement in Colourimetric Fluorescent Sensors (2024)
Preprint / Working Paper
Lu, Y., Dong, X., Ji, G., Wang, X., Wang, T., Tang, C., Ola, O., Duan, H., Liu, Q., & Niu, Q. Anchor Carbon Dots Inside Nh2-Mil-88b Via Ship-in-A-Bottle Strategy for Dual Signal Enhancement in Colourimetric Fluorescent Sensors

The increase in oxytetracycline (OTC) pollution has become a significant risk to both ecological stability and human health because of excessive use. Therefore, developing a precise and reliable sensor for detecting trace amounts of OTC is critical.... Read More about Anchor Carbon Dots Inside Nh2-Mil-88b Via Ship-in-A-Bottle Strategy for Dual Signal Enhancement in Colourimetric Fluorescent Sensors.

Highly Sensitive and Selective Detection of Ppb-Level Acetone Sensor Using Wo3/Au/Sno2 Ternary Composite Gas Sensor (2024)
Preprint / Working Paper
Zhu, X., Ola, O., Li, C., Gao, W., Wang, Z., Dai, C., Jiang, Y., Sun, S., & Chang, X. Highly Sensitive and Selective Detection of Ppb-Level Acetone Sensor Using Wo3/Au/Sno2 Ternary Composite Gas Sensor

Developing acetone sensors with high sensitivity and selectivity at ppb level is critical for medical diagnostics and environmental monitoring while facing serious challenges. In this work, we presented a ppb-level acetone sensor based on a WO3/Au/Sn... Read More about Highly Sensitive and Selective Detection of Ppb-Level Acetone Sensor Using Wo3/Au/Sno2 Ternary Composite Gas Sensor.

Provisions, Experiential Opportunities And Perceived Value Of Undergraduate Physiotherapy Clinical Placements Within Care Home Settings (2024)
Preprint / Working Paper
Cheng, K. S., Booth, V., Cowley, A., Robinson, K., & Logan, P. A. Provisions, Experiential Opportunities And Perceived Value Of Undergraduate Physiotherapy Clinical Placements Within Care Home Settings

Introduction
There is a growing ageing population who will live longer, but with a greater burden of comorbidity requiring care home placement. Despite evidence indicating that rehabilitation in long term care improves function and quality of life,... Read More about Provisions, Experiential Opportunities And Perceived Value Of Undergraduate Physiotherapy Clinical Placements Within Care Home Settings.

Structure and thermal stability of phosphorus-iodonium ylids (2024)
Preprint / Working Paper
Greener, A., P. Argent, S., Clarke, C., & L. O'Duill, M. Structure and thermal stability of phosphorus-iodonium ylids

Hypervalent iodine(III) reagents have become indispensable tools in organic synthesis, but gaps remain in the functionalities they can transfer. In this study, a fundamental understanding of the thermal stability of phosphorus-iodonium ylids is obtai... Read More about Structure and thermal stability of phosphorus-iodonium ylids.

Nonlinear Viscoelasticity of Filamentous Fungal Biofilms of Neurospora Discreta (2024)
Preprint / Working Paper
Narayanan Raghavan, A., M. Aiswarya, N., Tabraiz, S., Taneja, H., & Ahmed, A. Nonlinear Viscoelasticity of Filamentous Fungal Biofilms of Neurospora Discreta

The picture of bacterial biofilms as a colloidal gel composed of rigid bacterial cells protected by extracellular crosslinked polymer matrix has been pivotal in understanding their ability to adapt their microstructure and viscoelasticity to environm... Read More about Nonlinear Viscoelasticity of Filamentous Fungal Biofilms of Neurospora Discreta.

Optimising experimental designs for model selection of ion channel drug binding mechanisms (2024)
Preprint / Working Paper
Patten-Elliott, F., Lei, C. L., Preston, S. P., Wilkinson, R. D., & Mirams, G. R. Optimising experimental designs for model selection of ion channel drug binding mechanisms

The rapid delayed rectifier current carried by the human Ether-à-go-go-Related Gene (hERG) channel is susceptible to drug-induced reduction which can lead to an increased risk of cardiac arrhythmia. Establishing the mechanism by which a specific drug... Read More about Optimising experimental designs for model selection of ion channel drug binding mechanisms.

A Low-Complexity Modulated Model Predictive Current Control Scheme for PMSM based Starter Generator Control System in More Electric Aircraft (2024)
Preprint / Working Paper
Wang, Q., Yu, H., Li, C., Yeoh, S. S., Lang, X., Yang, T., Rivera, M., Bozhko, S., & Wheeler, P. A Low-Complexity Modulated Model Predictive Current Control Scheme for PMSM based Starter Generator Control System in More Electric Aircraft

Modulated model predictive control (M2PC) has recently emerged as a possible solution for control in starter generator systems in the more electric aircraft (MEA), due to its advantages of fixed switching frequency, fast response and good performance... Read More about A Low-Complexity Modulated Model Predictive Current Control Scheme for PMSM based Starter Generator Control System in More Electric Aircraft.

Evaluating the predictive accuracy of ion channel models using data from multiple experimental designs (2024)
Preprint / Working Paper
Shuttleworth, J. G., Lei, C. L., Windley, M. J., Hill, A. P., Preston, S. P., & Mirams, G. R. Evaluating the predictive accuracy of ion channel models using data from multiple experimental designs

Mathematical models are increasingly being relied upon to provide quantitatively accurate predictions of cardiac electrophysiology. Many such models concern the behaviour of particular subcellular components (namely, ion channels) which, together, al... Read More about Evaluating the predictive accuracy of ion channel models using data from multiple experimental designs.

A range of voltage-clamp protocol designs for rapid capture of hERG kinetics (2024)
Preprint / Working Paper
Lei, C. L., Whittaker, D. G., Windley, M. J., Perry, M. D., Hill, A. P., & Mirams, G. R. A range of voltage-clamp protocol designs for rapid capture of hERG kinetics

We provide details of a series of short voltage-clamp protocols designed for gathering a large amount of information on hERG (Kv11.1) ion channel gating. The protocols have a limited number of steps and consist only of steps and ramps, making them ea... Read More about A range of voltage-clamp protocol designs for rapid capture of hERG kinetics.

ENTRUST-PE: An Integrated Framework for Trustworthy Pain Evidence (2024)
Preprint / Working Paper
O'Connell, N., Richards, G. C., Soliman, N., Ferraro, M. C., Segelcke, D., Eccleston, C., Stewart, G., Smart, K. M., Palermo, T. M., Rice, A. S., Vollert, J., Wainwright, E., Williams, A., Crombez, G., Wilkinson, J., Pogatzki-Zahn, E., Turk, D., Keefe, F., Pickering, G., Knaggs, R., …Norris, E. ENTRUST-PE: An Integrated Framework for Trustworthy Pain Evidence

The personal, social and economic burden of chronic pain is enormous. Yet patients with chronic pain, clinicians and the public are often poorly served by an evidence architecture that contains multiple structural weaknesses which reduce confidence i... Read More about ENTRUST-PE: An Integrated Framework for Trustworthy Pain Evidence.

Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping (2024)
Preprint / Working Paper
Kyratzi, P., Matika, O., Brassington, A. H., Connie, C. E., Xu, J., Barrett, D. A., Emes, R. D., Archibald, A. L., Paldi, A., Sinclair, K. D., Wattis, J., & Rauch, C. Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping

Identifying associations between phenotype and genotype is the fundamental basis of genetic analyses. Inspired by frequentist probability and the work of R.A. Fisher, genome-wide association studies (GWAS) extract information using averages and varia... Read More about Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping.

The cultural construction of “executive function” (2024)
Preprint / Working Paper
Kroupin, I., Davis, H. E., Burdett, E., Cuata, A. B., Hartley, V., & Henrich, J. The cultural construction of “executive function”

In theory, the term "executive function" (EF) refers to universal features of the mind. Yet, almost all results described as measuring "EF" may actually reflect culturally-specific cognitive capacities. After all, typical EF measures require forms of... Read More about The cultural construction of “executive function”.

Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordings (2024)
Preprint / Working Paper
Lei, C. L., Clark, A. P., Clerx, M., Wei, S., Bloothooft, M., de Boer, T. P., Christini, D. J., Krogh-Madsen, T., & Mirams, G. R. Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordings

Cellular electrophysiology is the foundation of many fields, from basic science in neurology, cardiology, oncology to safety critical applications for drug safety testing, clinical phenotyping, etc. Patch-clamp voltage clamp is the gold standard tech... Read More about Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordings.

Theoretical and computational aspects of Hilbert-Maass forms (2024)
Preprint / Working Paper
Singh, S., & Strömberg, F. Theoretical and computational aspects of Hilbert-Maass forms

We introuce algorithms for computing Hilbert - Maass forms and present results obtained by using these algorithms. We also give an overview of the explicit Hecke theory for Hilbert -Maaass forms in the case of narrow class number one.

Applying Critical Discourse Analysis to Cross-Cultural Mental Health Recovery Research: Positive Changes and No Value Judgement (2024)
Preprint / Working Paper
Kotera, Y., Daryanani, R., Skipper, O., Jonathan Simpson, A., Takhi, S., McPhilbin, M., …Vilar-Lluch, S. Applying Critical Discourse Analysis to Cross-Cultural Mental Health Recovery Research: Positive Changes and No Value Judgement

The purpose of this paper is to demonstrate how Critical Discourse Analysis (CDA) frameworks can be used in cross-cultural mental health recovery research. CDA is a qualitative approach that critically appraises how language contributes to produce an... Read More about Applying Critical Discourse Analysis to Cross-Cultural Mental Health Recovery Research: Positive Changes and No Value Judgement.

Vivaldi: An amplicon-based whole genome sequencing method for the four seasonal human coronaviruses 229E, NL63, OC43 & HKU1, alongside SARS-CoV-2 (2024)
Preprint / Working Paper
McClure, C. P., Tsoleridis, T., Holmes, N., Chappell, J. G., Byaruhanga, T., Duncan, J., Tofan, M., Khater, A., Berry, L., Clark, G., Irving, W. L., Tarr, A. W., Ball, J. K., Astbury, S., & Loose, M. Vivaldi: An amplicon-based whole genome sequencing method for the four seasonal human coronaviruses 229E, NL63, OC43 & HKU1, alongside SARS-CoV-2

Prior to the emergence of SARS-CoV-2 in 2019, Alphacoronaviruses 229E and NL63 and Betacoronaviruses OC43 and HKU1 were already established endemic ‘common cold’ viral infections. Despite their collective contribution towards global respiratory morbi... Read More about Vivaldi: An amplicon-based whole genome sequencing method for the four seasonal human coronaviruses 229E, NL63, OC43 & HKU1, alongside SARS-CoV-2.

Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences (2024)
Preprint / Working Paper
Deakin, B., Liddle, E., Rathnaiah, M., Gregory, C., Katshu, M., Wiliams, G., Conen, S., Smallman, R., Koelewijn, L. C., Anton, A., Kumar, J., Gasgoyne, L. E., Chen, C., Nikkheslat, N., Evans, J., Lanz, B., Walters, J., Talbot, P., Palaniyappan, L., Singh, K. D., …Liddle, P. F. Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences

It is widely thought that the onset of psychotic symptoms in schizophrenia may arise from an early neurotoxic phase, possibly related to oxidative stress or inflammation, and a late residual damage phase associated with persistent negative symptoms.... Read More about Defining the disturbance in cortical glutamate and GABA function in psychosis and its origins and consequences.