All Outputs (28)
By the light of the moon.... (2020)
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By the light of the moon is the first in a series of short works for toy piano, piano and electronics that draw upon the poetry of Edward Lear. In this work, I start with the third verse of Lear’s famed poem, The Owl and the Pussy-cat, in which the c... Read More about By the light of the moon.....
Tumor Spheroids And Organoids Encyclopedia (2020)
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Understanding and investigating tumors is carried out by researchers using a number of different methods. One exciting and promising area is 3D tumor models including spheriod and organoid models. They act in similar ways to tumors which means we can... Read More about Tumor Spheroids And Organoids Encyclopedia.
Objectives To develop and validate a pragmatic risk score to predict mortality for patients admitted to hospital with covid-19. Design Prospective observational cohort study: ISARIC WHO CCP-UK study (ISARIC Coronavirus Clinical Characterisation Conso... Read More about Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.
This submission addresses the three questions formulated in the Joint Select Committee’s call with a particular focus on both the digital rights implications of the Government’s measures against COVID-19 and the wider human rights implications of the... Read More about Response to Call for Evidence – Joint Select Committee on Human Rights: The Government’s response to COVID-19: human rights implications.
Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles (2020)
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Protein orientation in nanoparticle-protein conjugates plays a crucial role in binding to cell receptors and ultimately, defines their targeting efficiency. Therefore, understanding fundamental aspects of the role of protein orientation upon adsorpti... Read More about Modulating the Biological Function of Protein by Tailoring the Adsorption Orientation on Nanoparticles.
The Modern Slavery (Victim Support) Bill: a cost-benefit analysis (2020)
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This report provides an analysis of the costs and benefits of extending support to adult conclusive victims of human trafficking in England and Wales for 12 months after exiting the National Referral Mechanism (NRM), the UK’s identification and suppo... Read More about The Modern Slavery (Victim Support) Bill: a cost-benefit analysis.
Background Patients with cystic fibrosis (CF) are characterised by abnormalities of the intestinal tract relating to gut motility and physiological issues, with daily symptoms of disease including abdominal pain, flatulence, bloating, and constipatio... Read More about Persistent intestinal abnormalities and symptoms in cystic fibrosis: The underpinning mechanisms impacting gut health and motility. Protocol for a systematic review..
Uclacyanin proteins are required for lignified nanodomain formation within Casparian strips (2020)
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Casparian strips (CS) are cell wall modifications of vascular plants restricting extracellular free diffusion into and out the vascular system. This barrier plays a critical role in controlling the acquisition of nutrients and water necessary for nor... Read More about Uclacyanin proteins are required for lignified nanodomain formation within Casparian strips.
Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol (2020)
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Objective: To characterize the clinical features of patients with severe COVID-19 in the UK. Design: Prospective observational cohort study with rapid data gathering and near real-time analysis, using a pre-approved questionnaire adopted by the WHO.... Read More about Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol.
Mitochondrial survivin reduces oxidative phosphorylation in cancer cells by inhibiting mitophagy. (2020)
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Survivin is a cancer-associated protein that is pivotal for cellular life and death: it is an essential mitotic protein and an inhibitor of apoptosis. In cancer cells, a small pool of survivin localises to the mitochondria, the function of which rema... Read More about Mitochondrial survivin reduces oxidative phosphorylation in cancer cells by inhibiting mitophagy..
Cyanobacteria are simple, efficient, genetically-tractable photosynthetic microorganisms representing ideal biocatalysts for CO2 capture and conversion, in principle. In practice, genetic instability and low productivity are key, linked problems in e... Read More about Combinatorial metabolic engineering platform enabling stable overproduction of lycopene from carbon dioxide by cyanobacteria.
Atomic Legacies (2020)
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This full-length album features two substantial semi-improvised original compositions for the magnetic resonator piano (MRP), "Glowing Radioactive Elements" for solo MRP (2018) and "Atomic Legacies" for MRP and string quartet (2019). The Magnetic... Read More about Atomic Legacies.
Coordinated prefrontal state transition leads extinction of reward-seeking behaviors (2020)
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Extinction learning suppresses conditioned reward responses and is thus fundamental to adapt to changing environmental demands and to control excessive reward seeking. The medial prefrontal cortex (mPFC) monitors and controls conditioned reward respo... Read More about Coordinated prefrontal state transition leads extinction of reward-seeking behaviors.