All Outputs (37872)

Caregiver strain in spouses of stroke patients (2003)
Journal Article

Objective: To test the ability of a previously generated logistic regression model to predict caregiver strain from carer mood, negative affectivity and perceived patient functional ability. Design: Postal prospective survey. Setting: Spouses o... Read More about Caregiver strain in spouses of stroke patients.

Transcriptional repression in eukaryotes: repressors and repression mechanisms (2003)
Journal Article

For many, if not most genes, the initiation of transcription is the principle point at which their expression is regulated. Transcription factors, some of which bind to specific DNA sequences, generally either activate or repress promoter activity an... Read More about Transcriptional repression in eukaryotes: repressors and repression mechanisms.

The Truro cordwainers' play: a "new" 18th century Christmas play (2003)
Journal Article

The Christmas play hitherto attributed to Mylor has been re-ascribed to Truro in the late 1780s, using biographical information concerning the actors, and physical characteristics of the manuscript. It becomes the oldest Saint George play to feature... Read More about The Truro cordwainers' play: a "new" 18th century Christmas play.

Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis (2003)
Journal Article

Calcitonin gene-related protein (CGRP) inhibits food intake and stimulates the hypothalamo-pituitary-adrenal (HPA) axis after intracerebroventricular injection in rats. However, the hypothalamic site and mechanism of action are unknown. We investigat... Read More about Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis.

Geographical inequalities in lung cancer management and survival in South East England: Evidence of variation in access to oncology services? (2003)
Journal Article

This study aimed to determine whether the management and survival of patients with lung cancer varied among 26 health authorities in South East England. The Thames Cancer Registry identified patients diagnosed with lung cancer (ICD-10 codes C33-C34)... Read More about Geographical inequalities in lung cancer management and survival in South East England: Evidence of variation in access to oncology services?.

Resistance to spontaneous apoptosis in acute myeloid leukaemia blasts is associated with p-glycoprotein expression and function, but not with the presence of FLT3 internal tandem duplications (2003)
Journal Article

The ability of acute myeloid leukaemia (AML) blasts to survive in culture has been associated with poor patient response to chemotherapy. Other biological factors predicting an adverse outcome include p-glycoprotein (pgp) expression, which is associa... Read More about Resistance to spontaneous apoptosis in acute myeloid leukaemia blasts is associated with p-glycoprotein expression and function, but not with the presence of FLT3 internal tandem duplications.

Liposome entrapment and immunogenic studies of a synthetic lipophilic multiple antigenic peptide bearing VP1 and VP3 domains of the hepatitis A virus: A robust method for vaccine design (2003)
Journal Article

Multiple antigen peptides (MAP) have been demonstrated to be efficient immunological reagents for the induction of immune responses to a variety of infectious agents. Several peptide domains of the hepatitis A virus (HAV) capsid proteins, mainly VP1... Read More about Liposome entrapment and immunogenic studies of a synthetic lipophilic multiple antigenic peptide bearing VP1 and VP3 domains of the hepatitis A virus: A robust method for vaccine design.

Flow cytometric measurement of phosphorylated STAT5 in AML: Lack of specific association with FLT3 internal tandem duplications (2003)
Journal Article

STAT5 phosphorylation has been noted in 69–95% of AML cases by Western blotting. We used flow cytometry to measure phosphorylated STAT5 on a semi-quantitative scale. The method was validated on K562 cells, which constitutively express phosphorylated... Read More about Flow cytometric measurement of phosphorylated STAT5 in AML: Lack of specific association with FLT3 internal tandem duplications.

Landau-Gutzwiller quasi-particles (2003)
Journal Article

We de?ne Landau quasiparticles within the Gutzwiller variational theory and derive their dispersion relation for general multiband Hubbard models in the limit of large spatial dimensions D. Thereby we reproduce our previous calculations which were ba... Read More about Landau-Gutzwiller quasi-particles.

An extensible event-based infrastructure for networked virtual worlds (2003)
Journal Article

Agouti-related protein has an inhibitory paracrine role in the rat adrenal gland (2003)
Journal Article

α-Melanocyte-stimulating-hormone (α-MSH) is an agonist at the melanocortin 3 receptor (MC3-R) and melanocortin 4 receptor (MC4-R). α-MSH stimulates corticosterone release from rat adrenal glomerulosa cells in vitro. Agouti-related protein (AgRP) an e... Read More about Agouti-related protein has an inhibitory paracrine role in the rat adrenal gland.

'On the Application of Hierarchical Coevolutionary Genetic Algorithms: Recombination and Evaluation Partners' (2003)
Journal Article

This paper examines the use of a hierarchical coevolutionary genetic algorithm under different partnering strategies. Cascading clusters of sub-populations are built from the bottom up, with higher-level sub-populations optimising larger parts of the... Read More about 'On the Application of Hierarchical Coevolutionary Genetic Algorithms: Recombination and Evaluation Partners'.

Adaptation of the MacNew quality of life questionnaire after myocardial infarction in an Iranian population (2003)
Journal Article

BACKGROUND: Health-related quality of life (HRQL) assessment is an important measure of the impact of a wide range of disease process on an individual. To date, no HRQL tool has been evaluated in an Iranian population with cardiovascular disorders, s... Read More about Adaptation of the MacNew quality of life questionnaire after myocardial infarction in an Iranian population.

Is quality of life measurement likely to be a proxy for health needs assessment in patients with coronary artery disease? (2003)
Journal Article

BACKGROUND: The identification of patients' health needs is pivotal in optimising the quality of health care, increasing patient satisfaction and directing resource allocation. Health needs are complex and not so easily evaluated as health-related qu... Read More about Is quality of life measurement likely to be a proxy for health needs assessment in patients with coronary artery disease?.

Need for redefining needs (2003)
Journal Article

Defining needs is difficult due to the inherent complexity of the concept of 'need', so it is not surprising that numerous definitions have been proposed. 'Health' consists of a wide range of characteristics so 'health needs' ought to include persona... Read More about Need for redefining needs.

Patients' satisfaction and quality of life in coronary artery disease (2003)
Journal Article

OBJECTIVES: To assess satisfaction of survivors of coronary artery diseases (CAD) with healthcare services and to determine whether specific components of standard health-related quality of life (HRQL) assessment tools might identify areas of satisfa... Read More about Patients' satisfaction and quality of life in coronary artery disease.

Unmet health needs in patients with coronary heart disease: implications and potential for improvement in caring services (2003)
Journal Article

BACKGROUND: Improving the quality of health care services requires tailoring facilities to fulfil patients' needs. Satisfying patients' healthcare needs, listening to patients' opinions and building a closer provider-user partnership are central to t... Read More about Unmet health needs in patients with coronary heart disease: implications and potential for improvement in caring services.

Local variation in helminth burdens of Egyptian spiny mice (Acomys cahirinus dimidiatus) from ecologically similar sites: relationships with hormone concentrations and social behaviour (2003)
Journal Article

Populations of Egyptian spiny mice (Acomys cahirinus dimidiatus) in a fragmented montane wadi system in the Sinai showed significant differences in the abundance of gut helminths. Differences in parasite load between populations were positively assoc... Read More about Local variation in helminth burdens of Egyptian spiny mice (Acomys cahirinus dimidiatus) from ecologically similar sites: relationships with hormone concentrations and social behaviour.

The test of compulsion in mental health law: capacity, therapeutic benefit, and dangerousness as criteria for compulsion (2003)
Journal Article

This paper considers three possible justifications for psychiatric compulsion - dangerousness, capacity and therapeutic benefit.

Paracrine effects of oocyte secreted factors and stem cell factor on porcine granulosa and theca cells in vitro (2003)
Journal Article

Oocyte control of granulosa and theca cell function may be mediated by several growth factors via a local feedback loop(s) between these cell types. This study examined both the role of oocyte-secreted factors on granulosa and thecal cells, cultured... Read More about Paracrine effects of oocyte secreted factors and stem cell factor on porcine granulosa and theca cells in vitro.