Association Between SGLT2 Inhibitor Treatment and Diabetic Ketoacidosis and Mortality in People With Type 2 Diabetes Admitted to Hospital With COVID-19

Khunti, Kamlesh; Ruan, Yue; Davies, Jim; Field, Benjamin C.T.; Harris, Sophie; Kosiborod, Mikhail; Nagi, Dinesh; Narendran, Parth; Patel, Dipesh; Ryder, Robert E.J.; Várnai, Kinga A.; Wild, Sarah H.; Wilmot, Emma G.; Rea, Rustam; Gandhi, Rajiv; Harris, Sophie; Nagi, Dinesh; Ryder, Robert; Davies, Jim; Harris, Steve; Freeman, Oliver; Maylor, Ben; Várnai, Kinga A.; Roadknight, Gail; Cull, Melissa; Ruan, Yue; Edwards, Amy; Gelding, Susan; Gunganah, Kirun; Aung, Pyei; Banerjee, Moulinath; Chakera, Ali; Rouse, Dominique; Ahmed, Syed Haris; Cheung, Ho Yee; Roberts, Hywel; Seal, Susan; Shah, Syed Saah; Hayat, Amir; Mohandas, Cynthia; Aung, Htet Htet; Chel, Su Khant; Lin, Nyan; Narula, Kavitia; Quadri, Furruq; Yin, Su Lei; Yin, Yin; Alkundi, Alamin; Musa, Abdelmajid; Birbeck, Emma; Bodmer, Charles; Bossman, Irene; Kumar, Sathis; Dashora, Umesh; Toubi, Elizabeth; Zafar, Mansoor; Patel, Vinod; Gopinath, Amitha; Allan, Belinda; Karim, Remat; Appuhamillage, Dharshana; Ayoub, Khubaib; Ilangaratne, Charmaine; Iqbal, Maliha; Maclean, Rory; Mustafa, Omar; Baxter, Susan; Adamus, Malgorzata; Baynes, Kevin; Sivappriyan, Siva; D’Costa, Ryan; Parfitt, Vernon; Islam, Mazharul; Nasir, Sadia; Várnai, Kinga; Vasan, Senthil; Devah, Vilashini Arul; Kavvoura, Foteini; Ficken, Lina; Gilham, James; Simpson, Vincent; Walker, Neil; Aziz, Umaira; Karra, Efthimia; Rosenthal, Miranda; Curran, Tracy; Paisley, Angela; De P, Parijat; Sarkar, Priscilla; Clark, James; Hogan, Vesna; Jackson, Lauren; Williamson, Jamie-Leigh; Younes, R.; Robin, Lucy; Grixti, Lydia; Tee, Suann; Sathya, Abilash; Patel, Mayank; Holmes, Catherine; Hanif, Wasim; Ghosh, Sandip; Ahmad, Ehtasham; Ahmed, Ejaz; Davies, Melanie; Hartshorn, Steven; Simons, Lee; Webb, David; Brahm, Anupam; Pramodh, Seshadri; Frew, Katy; Mackenzie, Alison; Wild, Abigail; Casey, Helen; Morrison, Deborah; McKeag, Conor; Sillars, Anne; Stirling, Angus; Smeeton, Fiona; Muhammad, Syed; Obuobie, Kofi; Yin, Win; Agarwal, Neera; Atkinson, Mike; Ambati, Sai; Khan, Rahim; Nalla, Preethi; Tabasum, Arshiya; Zouras, Stamatios; Mallipedhi, Akhila; Chudleigh, Richard; Williams, David

doi:10.2337/dc22-0357

All Outputs (2)

A nationwide study of adults admitted to hospital with diabetic ketoacidosis or hyperosmolar hyperglycaemic state and COVID‐19 (2023)
Journal Article
Field, B. C. T., Ruan, Y., Várnai, K. A., Davies, J., Ryder, R. E. J., Gandhi, R., …Williams, D. (2023). A nationwide study of adults admitted to hospital with diabetic ketoacidosis or hyperosmolar hyperglycaemic state and COVID‐19. Diabetes, Obesity and Metabolism, 25(7), 2012-2022. https://doi.org/10.1111/dom.15076

Aims To investigate characteristics of people hospitalized with coronavirus-disease-2019 (COVID-19) and diabetic ketoacidosis (DKA) or hyperosmolar hyperglycaemic state (HHS), and to identify risk factors for mortality and intensive care admission... Read More about A nationwide study of adults admitted to hospital with diabetic ketoacidosis or hyperosmolar hyperglycaemic state and COVID‐19.

Association Between SGLT2 Inhibitor Treatment and Diabetic Ketoacidosis and Mortality in People With Type 2 Diabetes Admitted to Hospital With COVID-19 (2022)
Journal Article
Khunti, K., Ruan, Y., Davies, J., Field, B. C., Harris, S., Kosiborod, M., …Williams, D. (2022). Association Between SGLT2 Inhibitor Treatment and Diabetic Ketoacidosis and Mortality in People With Type 2 Diabetes Admitted to Hospital With COVID-19. Diabetes Care, 45(12), 2838-2843. https://doi.org/10.2337/dc22-0357

OBJECTIVE To determine the association between prescription of SGLT2 inhibitors (SGLT2is) and diabetic ketoacidosis (DKA) incidence or mortality in people with type 2 diabetes (T2D) hospitalized with COVID-19. RESEARCH DESIGN AND METHODS This... Read More about Association Between SGLT2 Inhibitor Treatment and Diabetic Ketoacidosis and Mortality in People With Type 2 Diabetes Admitted to Hospital With COVID-19.