All Outputs (37973)

Real-world clinical effectiveness of ustekinumab in the treatment of Crohn’s disease in the East Midlands UK (2024)
Journal Article

Objectives: To evaluate the effectiveness of ustekinumab in treating Crohn’s disease (CD) in a UK real-world setting. Design: This was a multicentre, retrospective observational study of patients (aged ≥18 years) with CD or inflammatory bowel dise... Read More about Real-world clinical effectiveness of ustekinumab in the treatment of Crohn’s disease in the East Midlands UK.

Modeling reveals synergies among root traits for phosphorus acquisition in pearl millet (2024)
Journal Article

Pearl millet is a key food security grain crop in the world's drylands due to its tolerance to abiotic stresses. However, its yield remains low and is negatively impacted by climate change. Root phenes are potential targets to improve crop productivi... Read More about Modeling reveals synergies among root traits for phosphorus acquisition in pearl millet.

Enhancing the thermal cyclic reliability of salt-based shape-stabilized phase change materials by in-situ SiO2–C interconnectivity in rice husk carbon (2024)
Journal Article

Utilizing salt-based shape-stabilized phase change materials (ss-PCMs) for high-temperature thermal energy storage stands as a pivotal avenue in realizing carbon neutrality. However, the performance of ss-PCMs significantly deteriorates after thermal... Read More about Enhancing the thermal cyclic reliability of salt-based shape-stabilized phase change materials by in-situ SiO2–C interconnectivity in rice husk carbon.

Sub-optimal paternal diet at the time of mating disrupts maternal adaptations to pregnancy in the late gestation mouse (2024)
Journal Article

Pregnancy represents a stage during which maternal physiology and homeostatic regulation undergo dramatic change and adaptation. The fundamental purpose of these adaptations is to ensure the survival of her offspring through adequate nutrient provisi... Read More about Sub-optimal paternal diet at the time of mating disrupts maternal adaptations to pregnancy in the late gestation mouse.

Root-soil-microbiome management is key to the success of Regenerative Agriculture (2024)
Journal Article

Building soil health and manipulating the soil microbiome, alongside targeted plant breeding that prioritizes preferential root architectural development, hold the key to the future success of regenerative agriculture. Greater integration is needed b... Read More about Root-soil-microbiome management is key to the success of Regenerative Agriculture.

Future material demand and greenhouse gas emissions implications for electrification of the UK light-duty vehicle fleet (2024)
Journal Article

The UK zero-emissions vehicle (ZEV) mandate aims for battery electric vehicles (BEVs) to account for 100% of new sales by 2035. This study presents a fleet-scale life cycle assessment model of UK light duty vehicles through 2050, integrating a dynami... Read More about Future material demand and greenhouse gas emissions implications for electrification of the UK light-duty vehicle fleet.

'A huge political experiment' - exploring the political brand positioning of political parties in Jersey from an internal-external perspective (2024)
Journal Article

A political brand aims to project a differentiated and identifiable position in the minds of voters. However, there is limited understanding on the envisaged and realised positioning of political 'party' brands particularly in under-explored contexts... Read More about 'A huge political experiment' - exploring the political brand positioning of political parties in Jersey from an internal-external perspective.

Translating health promotion knowledge to self-care: healthy eating and weight management for nurses (2024)
Journal Article

Promoting health at work is a national public health priority. Nurses are educated in, and practice, health promotion but this knowledge does not always translate to self-care. There are high rates of overweight and obesity in nurses, with implicatio... Read More about Translating health promotion knowledge to self-care: healthy eating and weight management for nurses.

Area-metric gravity revisited (2024)
Journal Article

Area metrics are an intriguing generalization of length metrics which the generalization in several quantum-gravity approaches. We describe the space of diffeomorphism-invariant area-metric actions quadratic in fluctuations and derivatives. A general... Read More about Area-metric gravity revisited.

State-of-the-art in microwave processing of metals, metal powders and alloys (2024)
Journal Article

Discovery of the capacity of microwave energy to heat materials was a major milestone in the history of technology and scientific research. This discovery led to the development of many devices and processes that have replaced conventional heating me... Read More about State-of-the-art in microwave processing of metals, metal powders and alloys.

Addressing Equity, Diversity and Inclusion in JBI Qualitative Systematic Reviews: A Methodological Scoping Review (2024)
Journal Article

Objective: To investigate ways in which qualitative review teams are addressing equity, diversity and inclusion (EDI) in the process of conducting and reporting qualitative systematic reviews which utilize JBI guidelines. Introduction: In order to... Read More about Addressing Equity, Diversity and Inclusion in JBI Qualitative Systematic Reviews: A Methodological Scoping Review.

Challenges in Enhanced Recovery After Surgery (ERAS) Research (2024)
Journal Article

Molecular dynamics simulation of bulk nano-oxygen-bubble fuel under high-pressure transport and sudden pressure drop process (2024)
Journal Article

Aiming at the injection process of bubbly flow fuel, the molecular dynamics simulation was performed to study the change of bulk nano-oxygen-bubble (BNB) fuel during high-pressure transport and sudden pressure drop process. The static processes of BN... Read More about Molecular dynamics simulation of bulk nano-oxygen-bubble fuel under high-pressure transport and sudden pressure drop process.

High heteroplasmy is associated with low mitochondrial copy number and selection against non-synonymous mutations in the snail Cepaea nemoralis (2024)
Journal Article

Molluscan mitochondrial genomes are unusual because they show wide variation in size, radical genome rearrangements and frequently show high variation (>10%) within species. As progress in understanding this variation has been limited, we used whole... Read More about High heteroplasmy is associated with low mitochondrial copy number and selection against non-synonymous mutations in the snail Cepaea nemoralis.

Value-added Services and E-commerce Platform Competitiveness: A Game Theoretic Approach (2024)
Journal Article

Purpose-In response to the intense competition in the platform economy, e-commerce platforms are actively introducing value-added services to maintain their competitiveness. However, how effective these value-added services are in fulfilling this pur... Read More about Value-added Services and E-commerce Platform Competitiveness: A Game Theoretic Approach.

The acceptability of group B streptococcal bacteria (GBS) testing to women, including self-swabbing procedures: A qualitative study (2024)
Journal Article

Background: Group B streptococcus (GBS) is a bacterium carried by 20–25 % of pregnant women in the UK, which can be transmitted from pregnant women to their babies at the time of birth. Women can be tested for GBS in pregnancy using a vaginal-rectal... Read More about The acceptability of group B streptococcal bacteria (GBS) testing to women, including self-swabbing procedures: A qualitative study.

Searching for soil: Elucidating public interest in soil and soil conservation from 20 years of internet search trends (2024)
Journal Article

Over the last two decades, soil science research has undergone rapid expansion. Understanding public interest in soil science is vital for evaluating dissemination efforts and situating it in the broader environmental discourse. Analyzing Google Tren... Read More about Searching for soil: Elucidating public interest in soil and soil conservation from 20 years of internet search trends.

Cytomegalovirus, Epstein-Barr Virus, Herpes Simplex Virus, and Varicella Zoster Virus Infection Dynamics in People with Multiple Sclerosis from Northern Italy (2024)
Journal Article

Previous exposure to Epstein–Barr virus (EBV) is strongly associated with the development of multiple sclerosis (MS). By contrast, past cytomegalovirus (CMV) infection may have no association, or be negatively associated with MS. This study aimed to... Read More about Cytomegalovirus, Epstein-Barr Virus, Herpes Simplex Virus, and Varicella Zoster Virus Infection Dynamics in People with Multiple Sclerosis from Northern Italy.

Design, Synthesis, and Evaluation of a New Chemotype Fluorescent Ligand for the P2Y2 Receptor (2024)
Journal Article

The P2Y2 receptor (P2Y2R) is a target for diseases including cancer, idiopathic pulmonary fibrosis, and atherosclerosis. However, there are insufficient P2Y2R antagonists available for validating P2Y2R function and future drug development. Evaluation... Read More about Design, Synthesis, and Evaluation of a New Chemotype Fluorescent Ligand for the P2Y2 Receptor.

Comparative transcriptome reprogramming in oak galls containing asexual or sexual generations of gall wasps (2024)
Journal Article

Oak gall wasps have evolved strategies to manipulate the developmental pathways of their host to induce gall formation. This provides shelter and nutrients for the developing larva. Galls are entirely host tissue; however, the initiation, development... Read More about Comparative transcriptome reprogramming in oak galls containing asexual or sexual generations of gall wasps.