All Outputs (3403)

A dual material removal mechanism for clearing of obstructed holes via electrical discharge machining (2021)
Journal Article

Cooling hole blockages in gas turbine blades can occur during operation, detrimentally reducing performance and resulting in premature removal from service. Here, electrical discharge machining (EDM) is used to unblock fine holes, which have been obs... Read More about A dual material removal mechanism for clearing of obstructed holes via electrical discharge machining.

The DEVA trial: protocol for a randomised controlled trial of dequalinium chloride versus usual care antibiotics for the treatment of bacterial vaginosis (2021)
Journal Article

Background: Bacterial vaginosis (BV) is the most common cause of vaginal discharge in women of reproductive age, and it is estimated that up to a third of women will experience it at some point in their lives. BV produces an offensive vaginal odour a... Read More about The DEVA trial: protocol for a randomised controlled trial of dequalinium chloride versus usual care antibiotics for the treatment of bacterial vaginosis.

Vortex evolution in a rotating tank with an off-axis drain (2021)
Journal Article

Fluid entering the periphery of a steadily rotating cylindrical tank exits through an off-axis drain hole, located in the tank's base at the half-radius. Experiments show that, though a concentrated vortex forms over the drain, it soon advects around... Read More about Vortex evolution in a rotating tank with an off-axis drain.

FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer (2021)
Journal Article

Low-affinity immunoglobulin gamma Fc region receptor III-A (FcγRIIIa) is a cell surface protein that belongs to a family of Fc receptors that facilitate the protective function of the immune system against pathogens. However, the role of FcγRIIIa in... Read More about FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer.

SELCIE: a tool for investigating the chameleon field of arbitrary sources (2021)
Journal Article

The chameleon model is a modified gravity theory that introduces an additional scalar field that couples to matter through a conformal coupling. This `chameleon field' possesses a screening mechanism through a nonlinear self-interaction term which al... Read More about SELCIE: a tool for investigating the chameleon field of arbitrary sources.

Engineering bacteria to control electron transport altering the synthesis of non-native polymer (2021)
Journal Article

The use of bacteria as catalysts for radical polymerisations of synthetic monomers has recently been established. However, the role of trans Plasma Membrane Electron Transport (tPMET) in modulating these processes is not well understood. We sort to s... Read More about Engineering bacteria to control electron transport altering the synthesis of non-native polymer.

Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease (2021)
Journal Article

Background & Aims: Obesity-associated inflammation is a key player in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the role of macrophage scavenger receptor 1 (MSR1, CD204) remains incompletely understood. Methods: 170... Read More about Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease.

Topographic Control of Order in Quasi-2D Granular Phase Transitions (2021)
Journal Article

We experimentally investigate the nature of 2D phase transitions in a quasi-2D granular fluid. Using a surface decorated with periodically spaced dimples we observe interfacial tension between coexisting granular liquid and crystal phases. Measuremen... Read More about Topographic Control of Order in Quasi-2D Granular Phase Transitions.

RADIOHEAD: Radiogenomic analysis incorporating tumor heterogeneity in imaging through densities (2021)
Journal Article

Recent technological advancements have enabled detailed investigation of associations between the molecular architecture and tumor heterogeneity through multisource integration of radiological imaging and genomic (radiogenomic) data. In this paper we... Read More about RADIOHEAD: Radiogenomic analysis incorporating tumor heterogeneity in imaging through densities.

政府研发补贴与企业创新投入：数量激励抑或质量导向？ (2021)
Journal Article

如何有效发挥政府“有形之手”对企业创新的激励作用，优化公共资源配置效率，是实施创新驱动战略和推动经济高质量发展的关键一环。本文使用研发投资衡量创新投入数量，使用专利产出衡量创新投入转化质量，基于2001-2017年中国非金融类A股上市公司面板数据，从理论上分析政... Read More about 政府研发补贴与企业创新投入：数量激励抑或质量导向？.

Corrupted temporalities, ‘cultures of speed’, and the possibility of collegiality (2021)
Journal Article

This paper describes a neglected aspect of the critique of academic ‘cultures of speed’ offered by Maggie Berg and Barbara Seeler in The Slow Professor. I argue internalisation of the values and imperatives of cultures of speed can encourage the eros... Read More about Corrupted temporalities, ‘cultures of speed’, and the possibility of collegiality.

Optically Gated Terahertz-Field-Driven Switching of Antiferromagnetic CuMnAs (2021)
Journal Article

We show scalable and complete suppression of the recently reported terahertz-pulse-induced switching between different resistance states of antiferromagnetic CuMnAs thin films by ultrafast gating. The gating functionality is achieved by an optically... Read More about Optically Gated Terahertz-Field-Driven Switching of Antiferromagnetic CuMnAs.

Depressive symptoms, social support, and health-related quality of life: A community-based study in Shanghai, China (2021)
Journal Article

Background Depressive symptoms erode both physical and mental aspects of health-related quality of life (HRQoL). Social support (SS) may improve HRQoL through its direct effects or buffering effects. The association among depressive symptoms, SS, an... Read More about Depressive symptoms, social support, and health-related quality of life: A community-based study in Shanghai, China.

Activity and substrate specificity of lytic polysaccharide monooxygenases: An ATR FTIR-based sensitive assay tested on a novel species from Pseudomonas putida (2021)
Journal Article

Pseudomonas putida W619 is a soil Gram-negative bacterium commonly used in environmental studies thanks to its ability in degrading many aromatic compounds. Its genome contains several putative carbohydrate-active enzymes such as glycoside hydrolases... Read More about Activity and substrate specificity of lytic polysaccharide monooxygenases: An ATR FTIR-based sensitive assay tested on a novel species from Pseudomonas putida.

Reduced neutralisation of SARS-CoV-2 omicron B.1.1.529 variant by post-immunisation serum (2021)
Journal Article

Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial (2021)
Journal Article

Importance: In adults undergoing hip fracture surgery, regional anesthesia may reduce postoperative delirium, but there is uncertainty about its effectiveness. Objective: To investigate, in older adults undergoing surgical repair for hip fracture, th... Read More about Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial.

“I don’t want to take buprenorphine for the rest of my life”: Acceptance and Commitment Therapy for a Client Struggling to Reduce Low-Dose Buprenorphine (a Hermeneutic Single-Case Efficacy Design) (2021)
Journal Article

The misuse of substances is often maintained by both physical and psychological factors. Opioid-substitution medications manage physical aspects of addiction; however, difficulties with emotional regulation and avoidance perpetuate continued substanc... Read More about “I don’t want to take buprenorphine for the rest of my life”: Acceptance and Commitment Therapy for a Client Struggling to Reduce Low-Dose Buprenorphine (a Hermeneutic Single-Case Efficacy Design).

Measurement of the single crystal elasticity matrix of polycrystalline materials (2021)
Journal Article

Many engineering metals are polycrystalline, as such the elasticity, crystalline orientation and grain distribution are cardinal factors in determining the physical properties of the material. The grain distribution can be measured using a number of... Read More about Measurement of the single crystal elasticity matrix of polycrystalline materials.

Mutation and selection explain why many eukaryotic centromeric DNA sequences are often A+T rich (2021)
Journal Article

We have used chromosome engineering to replace native centromeric DNA with different test sequences at native centromeres in two different strains of the fission yeast Schizosaccharomyces pombe and have discovered that A + T rich DNA, whether synthet... Read More about Mutation and selection explain why many eukaryotic centromeric DNA sequences are often A+T rich.

TIME to Change: Rethinking Humanitarian Energy Access (2021)
Journal Article

Achieving Sustainable Development Goal 7-universal access to affordable, reliable and modern energy services by 2030-represents a considerable challenge. Currently, 40% of the global population do not have access to sustainable energy sources, and in... Read More about TIME to Change: Rethinking Humanitarian Energy Access.