All Outputs (3403)

Understanding the barriers and enablers of pharmacogenomic testing in primary care: a qualitative systematic review with meta-aggregation synthesis (2021)
Journal Article

Introduction: Pharmacogenomic testing can indicate which drugs may have limited therapeutic action or lead to adverse effects, hence guiding rational and safe prescribing. However, in the UK and other countries, there are still significant barriers t... Read More about Understanding the barriers and enablers of pharmacogenomic testing in primary care: a qualitative systematic review with meta-aggregation synthesis.

International data governance for neuroscience (2021)
Journal Article

As neuroscience projects increase in scale and cross international borders, different ethical principles, national and international laws, regulations, and policies for data sharing must be considered. These concerns are part of what is collectively... Read More about International data governance for neuroscience.

Kristin D. Hussey, Imperial Bodies in London: Empire, Mobility, and the Making of British Medicine, 1880–1914 (2021)
Journal Article

Self-Optimization of Continuous Flow Electrochemical Synthesis Using Fourier Transform Infrared Spectroscopy and Gas Chromatography (2021)
Journal Article

A continuous-flow electrochemical synthesis platform has been developed to enable self-optimization of reaction conditions of organic electrochemical reactions using attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR) and... Read More about Self-Optimization of Continuous Flow Electrochemical Synthesis Using Fourier Transform Infrared Spectroscopy and Gas Chromatography.

Neutron star scalarization with Gauss-Bonnet and Ricci scalar couplings (2021)
Journal Article

Spontaneous scalarization of neutron stars has been extensively studied in the Damour and Esposito-Farèse model, in which a scalar field couples to the Ricci scalar or, equivalently, to the trace of the energy-momentum tensor. However, scalarization... Read More about Neutron star scalarization with Gauss-Bonnet and Ricci scalar couplings.

Systematic Review with Meta-Analysis: Diagnostic Accuracy of Pro-C3 for Hepatic Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease (2021)
Journal Article

The prevalence and severity of non-alcoholic fatty liver disease (NAFLD) is increasing, yet adequately validated tests for care paths are limited and non-invasive markers of disease progression are urgently needed. The aim of this work was to summari... Read More about Systematic Review with Meta-Analysis: Diagnostic Accuracy of Pro-C3 for Hepatic Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease.

Optimising COVID-19 Vaccination Policy to Mitigate SARS-CoV-2 Transmission within Schools in Zimbabwe (2021)
Journal Article

The COVID-19 pandemic has disrupted the learning of millions of children across the world. Since March 2020 when the first cases of COVID-19 were reported in Zimbabwe, the country, like many others, has gone through periods of closing and re-opening... Read More about Optimising COVID-19 Vaccination Policy to Mitigate SARS-CoV-2 Transmission within Schools in Zimbabwe.

Apoferritin and Dps as drug delivery vehicles: Some selected examples in oncology (2021)
Journal Article

Background: The ideal nanoparticle should be able to encapsulate either pharmaceutical agents or imaging probes so that it could treat or image clinical tumours by targeting the cancer site efficiently. Further, it would be an added advantage if it d... Read More about Apoferritin and Dps as drug delivery vehicles: Some selected examples in oncology.

The impact of COVID-19 on the wellbeing of the UK nursing and midwifery workforce during the first pandemic wave: A longitudinal survey study (2021)
Journal Article

Background: The specific challenges experienced by the nursing and midwifery workforce in previous pandemics have exacerbated pre-existing professional and personal challenges, and triggered new issues. We aimed to determine the psychological impact... Read More about The impact of COVID-19 on the wellbeing of the UK nursing and midwifery workforce during the first pandemic wave: A longitudinal survey study.

This is Me: Evaluation of a boardgame to promote social engagement, wellbeing and agency in people with dementia through mindful life-storytelling (2021)
Journal Article

Receiving a dementia diagnosis is a difficult experience for most people and often affects their wellbeing negatively. To support people's wellbeing, in a therapeutic context, life-storytelling, reminiscence and mindfulness are used with people with... Read More about This is Me: Evaluation of a boardgame to promote social engagement, wellbeing and agency in people with dementia through mindful life-storytelling.

Infantographies (2021)
Journal Article

Maternal prenatal anxiety and depression and trajectories of cardiometabolic risk factors across childhood and adolescence: a prospective cohort study (2021)
Journal Article

Objectives: Quantifying long-term offspring cardiometabolic health risks associated with maternal prenatal anxiety and depression can guide cardiometabolic risk prevention. This study examines associations between maternal prenatal anxiety and depres... Read More about Maternal prenatal anxiety and depression and trajectories of cardiometabolic risk factors across childhood and adolescence: a prospective cohort study.

Saliva for COVID-19 testing: Simple but useless or an undervalued resource? (2021)
Journal Article

During the COVID-19 pandemic, countries with robust population-based asymptomatic testing were generally successful in controlling virus spread, hence reducing hospitalizations and deaths. This effectiveness inspired widespread asymptomatic surveilla... Read More about Saliva for COVID-19 testing: Simple but useless or an undervalued resource?.

Estimating divergence‐free flows via neural networks (2021)
Journal Article

We apply neural networks to the problem of estimating divergence-free velocity flows from given sparse observations. Following the modern trend of combining data and models in physics-informed neural networks, we reconstruct the velocity flow by trai... Read More about Estimating divergence‐free flows via neural networks.

Brain structural covariance network differences in adults with alcohol dependence and heavy-drinking adolescents (2021)
Journal Article

BACKGROUND AND AIMS: Graph theoretic analysis of structural covariance networks (SCN) provides an assessment of brain organization that has not yet been applied to alcohol dependence (AD). We estimated whether SCN differences are present in adults wi... Read More about Brain structural covariance network differences in adults with alcohol dependence and heavy-drinking adolescents.

Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress (2021)
Journal Article

N-methyl-D-aspartate receptor (NMDAR) overstimulation is known to mediate neurodegeneration, and hence represents a relevant therapeutic target for neurodegenerative disorders including glaucoma. This study examined the neuroprotective effects of phi... Read More about Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress.

A multi-scale integrated assessment model to support urban sustainability (2021)
Journal Article

Tools purposed towards supporting the transition to more sustainable urban futures typically focus on specific phenomena at the local level. Whilst such approaches remain valuable, there is a need to complement this micro approach with broader integr... Read More about A multi-scale integrated assessment model to support urban sustainability.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection (2021)
Journal Article

Although myocarditis and pericarditis were not observed as adverse events in coronavirus disease 2019 (COVID-19) vaccine trials, there have been numerous reports of suspected cases following vaccination in the general population. We undertook a self-... Read More about Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection.

Seismic response of piles in layered soils: Performance of pseudostatic Winkler models against centrifuge data (2021)
Journal Article

In this study, the suitability of the pseudostatic approach for the seismic analysis of pile foundations in layered soils is explored by means of experimental data from centrifuge tests performed at 60g. A free-head single pile and a capped (1 × 3) p... Read More about Seismic response of piles in layered soils: Performance of pseudostatic Winkler models against centrifuge data.

A review on second-life of Li-ion batteries: prospects, challenges, and issues (2021)
Journal Article

High energy density has made Li-ion battery become a reliable energy storage technology for transport-grid applications. Safely disposing batteries that below 80% of their nominal capacity is a matter of great concern to reduce overall carbon footpri... Read More about A review on second-life of Li-ion batteries: prospects, challenges, and issues.