All Outputs (5)

Applying asymptotic methods to synthetic biology: modelling the reaction kinetics of the mevalonate pathway (2017)
Journal Article
Dalwadi, M. P., Garavaglia, M., Webb, J. P., King, J. R., & Minton, N. P. (2018). Applying asymptotic methods to synthetic biology: modelling the reaction kinetics of the mevalonate pathway. Journal of Theoretical Biology, 439, https://doi.org/10.1016/j.jtbi.2017.11.022

The mevalonate pathway is normally found in eukaryotes, and allows for the production of isoprenoids, a useful class of organic compounds. This pathway has been successfully introduced to Escherichia coli, enabling a biosynthetic production route for... Read More about Applying asymptotic methods to synthetic biology: modelling the reaction kinetics of the mevalonate pathway.

New type I ancient compact solutions of the Yamabe flow (2017)
Journal Article
Daskalopoulos, P., del Pino, M., King, J., & Sesum, N. (2017). New type I ancient compact solutions of the Yamabe flow. Mathematical Research Letters, 24(6), 1667-1691. https://doi.org/10.4310/MRL.2017.v24.n6.a5

We construct new ancient compact solutions to the Yamabe flow. Our solutions are rotationally symmetric and converge, as t???, to two self-similar complete non-compact solutions to the Yamabe flow moving in opposite directions. They are type I ancien... Read More about New type I ancient compact solutions of the Yamabe flow.

Multi-timescale analysis of a metabolic network in synthetic biology: a kinetic model for 3-hydroxypropionic acid production via beta-alanine (2017)
Journal Article
Dalwadi, M. P., King, J. R., & Minton, N. P. (2018). Multi-timescale analysis of a metabolic network in synthetic biology: a kinetic model for 3-hydroxypropionic acid production via beta-alanine. Journal of Mathematical Biology, 77(1), 165-199. https://doi.org/10.1007/s00285-017-1189-3

A biosustainable production route for 3-hydroxypropionic acid (3HP), an important platform chemical, would allow 3HP to be produced without using fossil fuels. We are interested in investigating a potential biochemical route to 3HP from pyruvate thro... Read More about Multi-timescale analysis of a metabolic network in synthetic biology: a kinetic model for 3-hydroxypropionic acid production via beta-alanine.

Stress-dependent local oxidation of silicon (2017)
Journal Article
Evans, J. D., & King, J. R. (2017). Stress-dependent local oxidation of silicon. SIAM Journal on Applied Mathematics, 77(6), 2012-2039. https://doi.org/10.1137/16M1060613

The two-dimensional isolation oxidation of silicon is considered for stress-dependent reaction and diffusion coefficients. The influence of such parameters is investigated numerically and asymptotically in the bird's beak problem and for curved geome... Read More about Stress-dependent local oxidation of silicon.

Root hydrotropism is controlled via a cortex-specific growth mechanism (2017)
Journal Article
Dietrich, D., Pang, L., Kobayashi, A., Fozard, J. A., Boudolf, V., Bhosale, R., …Bennett, M. J. (2017). Root hydrotropism is controlled via a cortex-specific growth mechanism. Nature Plants, 3(6), Article 17057. https://doi.org/10.1038/nplants.2017.57

Plants can acclimate by using tropisms to link the direction of growth to environmental conditions. Hydrotropism allows roots to forage for water, a process known to depend on abscisic acid (ABA) but whose molecular and cellular basis remains unclear... Read More about Root hydrotropism is controlled via a cortex-specific growth mechanism.