All Outputs (8)

Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome (2017)
Journal Article
Syed, B. M., Morgan, D., Setty, T., Green, A. R., Paish, E. C., Ellis, I. O., & Cheung, K. (2017). Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome. PLoS ONE, 12(12), Article e0188528. https://doi.org/10.1371/journal.pone.0188528

Background Older women are at the greatest risk of breast cancer development and a considerable number present with comorbidities. Although the majority of breast cancers in this age group express oestrogen receptor (ER), which makes endocrine the... Read More about Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome.

4th symposium on primary breast cancer in older women. Theme: putting personalized care into practice (held: 3 March 2017) (2017)
Journal Article
Cheung, K., Morgan, D., Brain, E., Poortmans, P., Parks, R., Korc-Grodzicki, B., …Wijayatunga, R. (in press). 4th symposium on primary breast cancer in older women. Theme: putting personalized care into practice (held: 3 March 2017). Breast Cancer Management, https://doi.org/10.2217/bmt-2017-0016

Following the inception in 2010, the University of Nottingham hosted the 4th Symposium on Primary Breast Cancer in Older Women, under the auspices of the International Society of Geriatric Oncology, in March 2017, at East Midlands Conference Centre.... Read More about 4th symposium on primary breast cancer in older women. Theme: putting personalized care into practice (held: 3 March 2017).

A continuing mission to optimize the care of older women with breast cancer (2017)
Journal Article
Cheung, K. (2017). A continuing mission to optimize the care of older women with breast cancer. Geriatrics, 2(4), Article 37. https://doi.org/10.3390/geriatrics2040037

The majority of cases of breast cancer occur in the older population who are often un-represented in clinical trials. Given the growing ageing population globally, it becomes urgent and important to identify an optimal approach so that older women wi... Read More about A continuing mission to optimize the care of older women with breast cancer.

Tumour boards in geriatric oncology (2017)
Journal Article
Wildes, T. M., O'Donovan, A., Colloca, G. F., & Cheung, K. (2018). Tumour boards in geriatric oncology. Age and Ageing, 47(2), 168-170. https://doi.org/10.1093/ageing/afx171

Multidisciplinary tumour board (MDT) is an integral part of cancer treatment planning. Although no definite survival benefits have yet been shown by mostly observational studies, other benefits of MDT have been identified. Traditionally the MDT invol... Read More about Tumour boards in geriatric oncology.

Controversial issues in the management of older adults with early breast cancer (2017)
Journal Article
Mislang, A. R., Cheung, K., Hamaker, M. E., Kunkler, I., Markopoulos, C., Orecchia, R., …Biganzoli, L. (in press). Controversial issues in the management of older adults with early breast cancer. Journal of Geriatric Oncology, https://doi.org/10.1016/j.jgo.2017.05.004

It is well recognized that the incidence of breast cancer increases significantly with age. Despite this, older people remain under-represented in many clinical trials and their management relies on extrapolation of data from younger patients. Provid... Read More about Controversial issues in the management of older adults with early breast cancer.

Axillary reverse mapping in N0 patients requiring sentinel lymph node biopsy: a systematic review of the literature and necessity of a randomised study (2017)
Journal Article
Parks, R., & Cheung, K. (2017). Axillary reverse mapping in N0 patients requiring sentinel lymph node biopsy: a systematic review of the literature and necessity of a randomised study. Breast, 33, https://doi.org/10.1016/j.breast.2017.02.019

Objectives: Axillary reverse mapping (ARM) is a technique to map and preserve arm lymphatics which may be damaged during surgery, resulting in lymphoedema. This work systematically reviews the incidence of lymphoedema following sentinel lymph node bi... Read More about Axillary reverse mapping in N0 patients requiring sentinel lymph node biopsy: a systematic review of the literature and necessity of a randomised study.

What influences healthcare professionals' treatment preferences for older women with operable breast cancer?: an application of the discrete choice experiment (2017)
Journal Article
Morgan, J., Walters, S., Collins, K., Robinson, T., Cheung, K., Audisio, R., …Wyld, L. (2017). What influences healthcare professionals' treatment preferences for older women with operable breast cancer?: an application of the discrete choice experiment. EJSO - European Journal of Surgical Oncology, 43(7), https://doi.org/10.1016/j.ejso.2017.01.012

Introduction Primary endocrine therapy (PET) is used variably in the UK as an alternative to surgery for older women with operable breast cancer. Guidelines state that only patients with “significant comorbidity” or “reduced life expectancy” shoul... Read More about What influences healthcare professionals' treatment preferences for older women with operable breast cancer?: an application of the discrete choice experiment.

Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer (2017)
Journal Article
Alexander, A., Karakas, C., Chen, X., Carey, J. P., Yi, M., Bondy, M., …Keyomarsi, K. (2017). Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer. Oncotarget, 8, 14897-14911. https://doi.org/10.18632/oncotarget.14689

Inflammatory breast cancer (IBC) is a virulent form of breast cancer, and novel treatment strategies are urgently needed. Immunohistochemical analysis of tumors from women with a clinical diagnosis of IBC (n = 147) and those with non-IBC breast cance... Read More about Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer.