All Outputs (2)

An Immune-Inspired Technique to Identify Heavy Goods Vehicles Incident Hot Spots (2017)
Journal Article
Figueredo, G. P., Triguero, I., Mesgarpour, M., Maciel Guerra, A., Garibaldi, J. M., & John, R. (2017). An Immune-Inspired Technique to Identify Heavy Goods Vehicles Incident Hot Spots. IEEE Transactions on Emerging Topics in Computational Intelligence, 1(4), 248-258. https://doi.org/10.1109/TETCI.2017.2721960

We report on the adaptation of an immune-inspired instance selection technique to solve a real-world big data problem of determining vehicle incident hot spots. The technique, which is inspired by the Immune System self-regulation mechanism, was orig... Read More about An Immune-Inspired Technique to Identify Heavy Goods Vehicles Incident Hot Spots.

A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing (2017)
Journal Article
Figueredo, G., Todd, I., Negm, O. H., Reps, J., Radford, P., Figueredo, G. P., …Tighe, P. J. (2017). A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing. Pharmacological Research, 125, 188-200. https://doi.org/10.1016/j.phrs.2017.08.012

© 2017 Elsevier Ltd TNF receptor associated periodic syndrome (TRAPS) is an autoinflammatory disease caused by mutations in TNF Receptor 1 (TNFR1). Current therapies for TRAPS are limited and do not target the pro-inflammatory signalling pathways tha... Read More about A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing.