All Outputs (2)

Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition (2016)
Journal Article
Kachel, H. S., Patel, R. N., Franzyk, H., & Mellor, I. R. (2016). Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition. Scientific Reports, 6, https://doi.org/10.1038/srep38116

Philanthotoxin-433 (PhTX-433) is an active component of the venom from the Egyptian digger wasp, Philanthus triangulum. PhTX-433 inhibits several excitatory ligand-gated ion channels, and to improve selectivity two synthetic analogues, PhTX-343 and P... Read More about Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition.

Insecticide resistance mediated 1 by an exon skipping event (2016)
Journal Article
Berger, M., Puinean, A. M., Randall, E., Zimmer, C. T., Silva, W. M., Bielza, P., …Bass, C. (2016). Insecticide resistance mediated 1 by an exon skipping event. Molecular Ecology, 25(22), https://doi.org/10.1111/mec.13882

Many genes increase coding capacity by alternate exon usage. The gene encoding the insect nicotinic acetylcholine receptor (nAChR) a6 subunit, target of the bio-insecticide spinosad, is one example of this and expands protein diversity via alternativ... Read More about Insecticide resistance mediated 1 by an exon skipping event.