All Outputs (1154)

Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan (2013)
Journal Article
Kuo, C., Grainge, M. J., See, L., Yu, K., Luo, S., Valdes, A. M., …Doherty, M. (2015). Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan. Annals of the Rheumatic Diseases, 74(2), 369-374. https://doi.org/10.1136/annrheumdis-2013-204067

© 2015, BMJ Publishing Group. All rights reserved. Objective: To examine familial aggregation of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population. Methods: Using data from the Nati... Read More about Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan.

Urinary excretion of ginkgolide terpene lactones following acute consumption ofGinkgo bilobaextract: Dose-Dependent Urinary Excretion of Ginkgolides (2013)
Journal Article
Dew, T. P., Wang, G., & Williamson, G. (2014). Urinary excretion of ginkgolide terpene lactones following acute consumption ofGinkgo bilobaextract: Dose-Dependent Urinary Excretion of Ginkgolides. BioFactors, 40(2), 268-274. https://doi.org/10.1002/biof.1151

Urinary biomarkers of plant food supplement (PFS) exposure/intake represent an accurate, objective tool for determining PFS consumption in humans with applications ranging from epidemiology to subject compliance in clinical trials. Ginkgo biloba rema... Read More about Urinary excretion of ginkgolide terpene lactones following acute consumption ofGinkgo bilobaextract: Dose-Dependent Urinary Excretion of Ginkgolides.

The practice and poetics of fieldwork: Hugh Cott and the study of camouflage (2013)
Journal Article
Forsyth, I. (2014). The practice and poetics of fieldwork: Hugh Cott and the study of camouflage. Journal of Historical Geography, 43, 128-137. https://doi.org/10.1016/j.jhg.2013.10.002

This paper examines the practice and poetics of the British zoologist Hugh Cott's fieldwork in order to explore the hybrid nature of developments in biological and military camouflage. Specifically focusing on two fieldtrips conducted to the Amazon a... Read More about The practice and poetics of fieldwork: Hugh Cott and the study of camouflage.

Finite element investigation of the effect of spina bifida on loading of the vertebral isthmus (2013)
Journal Article
Quah, C., Yeoman, M. S., Cizinauskas, A., Cooper, K., McNally, D., & Boszczyk, B. (2014). Finite element investigation of the effect of spina bifida on loading of the vertebral isthmus. Spine Journal, 14(4), https://doi.org/10.1016/j.spinee.2013.08.040

Background: Spondylolysis (SL) of the lower lumbar spine is frequently associated with spina bifida occulta (SBO). There has not been any study that has demonstrated biomechanical or genetic predispositions to explain the coexistence of these two pat... Read More about Finite element investigation of the effect of spina bifida on loading of the vertebral isthmus.

Insulin-like factor 3 as a monitor of endocrine disruption (2013)
Journal Article
Anand-Ivell, R., & Ivell, R. (2014). Insulin-like factor 3 as a monitor of endocrine disruption. Reproduction, 147, Article R87-R95. https://doi.org/10.1530/REP-13-0486

Insulin-like factor 3 (INSL3) is generated and secreted by differentiated interstitial Leydig cells of the testes in both fetal and adult males of all mammalian species so far analyzed. All evidence to date suggests that it is produced constitutively... Read More about Insulin-like factor 3 as a monitor of endocrine disruption.

Effects of dehydroepiandrosterone on in vivo ovine follicular development (2013)
Journal Article
Narkwichean, A., Jayaprakasan, K., Maalouf, W. E., Hernandez-Medrano, J., Pincott-Allen, C., & Campbell, B. K. (2014). Effects of dehydroepiandrosterone on in vivo ovine follicular development. Human Reproduction, 29(1), https://doi.org/10.1093/humrep/det408

STUDY QUESTION: What are the effects of exposure of ovarian tissue to dehydroepiandrosterone (DHEA) supplementation in vivo? SUMMARY ANSWER:DHEA exposure stimulates initiation of primordial follicles and development of gonadotrophin-responsive prean... Read More about Effects of dehydroepiandrosterone on in vivo ovine follicular development.

Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10 (2013)
Journal Article
Franks, H. A., Wang, Q., Lax, S. J., Colllins, M. K., Escors, D., Patel, P. M., & Jackson, A. M. (2014). Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10. International Journal of Cancer, 134(3), 575-586. https://doi.org/10.1002/ijc.28398

There is growing interest in myeloid (my) dendritic cells (DC) as an alternative to monocyte-derived DC (moDC) for immunotherapy. However, in contrast to moDC, little is known regarding the effect of malignancy on the function, abundance or use of in... Read More about Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10.

A female-emitted pheromone component is associated with reduced male courtship in the parasitoid wasp Spalangia endius (2013)
Journal Article
Mowles, S. L., King, B. H., Linforth, R. S., & Hardy, I. C. (2013). A female-emitted pheromone component is associated with reduced male courtship in the parasitoid wasp Spalangia endius. PLoS ONE, 8(11), Article e82010. https://doi.org/10.1371/journal.pone.0082010

During courtship interactions, the courted individual may not always be prepared to mate. For example, mating or courtship may be detrimental to its fitness and resistance is expected under these circumstances. As such, various resistance strategies... Read More about A female-emitted pheromone component is associated with reduced male courtship in the parasitoid wasp Spalangia endius.

The one-dimensional Lyα forest power spectrum from BOSS (2013)
Journal Article
Palanque-Delabrouille, N., Yèche, C., Borde, A., Le Goff, J.-M., Rossi, G., Viel, M., …Weinberg, D. H. (2013). The one-dimensional Lyα forest power spectrum from BOSS. Astronomy and Astrophysics, 559, Article A85. https://doi.org/10.1051/0004-6361/201322130

We have developed two independent methods for measuring the one-dimensional power spectrum of the transmitted flux in the Lyman-α forest. The first method is based on a Fourier transform and the second on a maximum-likelihood estimator. The two metho... Read More about The one-dimensional Lyα forest power spectrum from BOSS.

Three unobtrusive domestic occupancy measurement technologies under qualitative review (2013)
Journal Article
Naghiyev, E., Gillott, M., & WILSON, R. (2014). Three unobtrusive domestic occupancy measurement technologies under qualitative review. Energy and Buildings, 69, 507-514. https://doi.org/10.1016/j.enbuild.2013.11.033

Almost one third of the UK's total energy is consumed by the domestic sector. Occupancy measurement could have the potential to save significant amounts of that energy, either instantly via a home automation system or retrospectively via post-occupan... Read More about Three unobtrusive domestic occupancy measurement technologies under qualitative review.

Dynamic capital structure and political patronage: the case of Malaysia (2013)
Journal Article
Ebrahim, M. S., Girma, S., Shah, M. E., & Williams, J. (2014). Dynamic capital structure and political patronage: the case of Malaysia. International Review of Financial Analysis, 31, https://doi.org/10.1016/j.irfa.2013.11.004

This paper investigates the effect of political patronage on firms' capital structure. The evidence is from Malaysia, a country characterised by relationship-capitalism, and covers 1988 to 2009. Using a system GMM estimator we find firms set leverage... Read More about Dynamic capital structure and political patronage: the case of Malaysia.

Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment (2013)
Journal Article
Hutchings, C. J., Cseke, G., Osborne, G., Woolard, J., Zhukov, A., Koglin, M., …Marshall, F. H. (2014). Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment. mAbs, 6(1), 246-261. https://doi.org/10.4161/mabs.27226

Thermostabilized G protein-coupled receptors used as antigens for in vivo immunization have resulted in the generation of functional agonistic anti-β1-adrenergic (β1AR) receptor monoclonal antibodies (mAbs). The focus of this study was to examine the... Read More about Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment.

PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin (2013)
Journal Article
Kershaw, R. M., Siddiqui, Y. H., Roberts, D., Jayaraman, P.-S., & Gaston, K. (2014). PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin. Oncogene, 33, 5592-5600. https://doi.org/10.1038/onc.2013.496

PRH/HHex (proline-rich homeodomain protein) is a transcription factor that controls cell proliferation and cell differentiation in a variety of tissues. Aberrant subcellular localisation of PRH is associated with breast cancer and thyroid cancer. Fur... Read More about PRH/HHex inhibits the migration of breast and prostate epithelial cells through direct transcriptional regulation of Endoglin.

Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels (2013)
Journal Article
Portelli, M., Siedlinski, M., Stewart, C. E., Postma, D. S., Nieuwenhuis, M. A., Vonk, J. M., …Sayers, I. (2013). Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB Journal, 28(2), https://doi.org/10.1096/fj.13-240879

The soluble cleaved urokinase plasminogen activator receptor (scuPAR) is a circulating protein detected in multiple diseases, including various cancers, cardiovascular disease, and kidney disease, where elevated levels of scuPAR have been associated... Read More about Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels.

Use of contrast-enhanced ultrasonography in chronic pathologic canine testes (2013)
Journal Article
Volta, A., Manfredi, S., Vignoli, M., Russo, M., England, G., Rossi, F., …Gnudi, G. (2014). Use of contrast-enhanced ultrasonography in chronic pathologic canine testes. Reproduction in Domestic Animals, 49(2), https://doi.org/10.1111/rda.12250

Contrast-enhanced ultrasound with sulphur hexafluoride microbubbles was performed in seven healthy dogs without a history of reproductive pathology and with histologically confirmed normal testes and in 42 dogs with chronic scrotal anomalies. All dog... Read More about Use of contrast-enhanced ultrasonography in chronic pathologic canine testes.

Visual motion integration is mediated by directional ambiguities in local motion signals (2013)
Journal Article
Rocchi, F., Ledgeway, T., & Webb, B. S. (2013). Visual motion integration is mediated by directional ambiguities in local motion signals. Frontiers in Computational Neuroscience, 7, Article 167. https://doi.org/10.3389/fncom.2013.00167

The output of primary visual cortex (V1) is a piecemeal representation of the visual scene and the response of any one cell cannot unambiguously guide sensorimotor behavior. It remains unsolved how subsequent stages of cortical processing combine (“p... Read More about Visual motion integration is mediated by directional ambiguities in local motion signals.

Understanding the acceleration in the ring-opening of lactones delivered by microwave heating (2013)
Journal Article
Nguyen, N. T., Greenhalgh, E., Kamaruddin, M. J., El harfi, J., Carmichael, K., Dimitrakis, G., …Irvine, D. J. (2014). Understanding the acceleration in the ring-opening of lactones delivered by microwave heating. Tetrahedron, 70(4), 996-1003. https://doi.org/10.1016/j.tet.2013.11.031

Mapping and validation of quantitative trait loci associated with concentrations of 16 elements in unmilled rice grain (2013)
Journal Article
Zhang, M., Pinson, S. R., Tarpley, L., Huang, X., Lahner, B., Yakubova, E., …Salt, D. E. (2014). Mapping and validation of quantitative trait loci associated with concentrations of 16 elements in unmilled rice grain. TAG Theoretical and Applied Genetics, 127(1), 137-165. https://doi.org/10.1007/s00122-013-2207-5

Key Message: QTLs controlling the concentrations elements in rice grain were identified in two mapping populations. The QTLs were clustered such that most genomic regions were associated with more than one element. In this study, quantitative tra... Read More about Mapping and validation of quantitative trait loci associated with concentrations of 16 elements in unmilled rice grain.

The relationship between MEG and fMRI (2013)
Journal Article
Hall, E. L., Robson, S., Morris, P., & Brookes, M. J. (2014). The relationship between MEG and fMRI. NeuroImage, 102(1), https://doi.org/10.1016/j.neuroimage.2013.11.005

In recent years functional neuroimaging techniques such as fMRI, MEG, EEG and PET have provided researchers with a wealth of information on human brain function. However none of these modalities can measure directly either the neuro-electrical or ne... Read More about The relationship between MEG and fMRI.

Searching for large-scale structures around high-redshift radio galaxies with Herschel (2013)
Journal Article
Rigby, E., Hatch, N. A., Rottgering, H., Sibthorpe, B., Chiang, Y., Overzier, R., …Venemans, B. (2014). Searching for large-scale structures around high-redshift radio galaxies with Herschel. Monthly Notices of the Royal Astronomical Society, 437(2), https://doi.org/10.1093/mnras/stt2019

This paper presents the first results of a far-infrared search for protocluster-associated galaxy overdensities using the Spectral and Photometric Imaging REciever (SPIRE) instrument on-board the Herschel Space Observatory. Large (∼400 arcmin2) field... Read More about Searching for large-scale structures around high-redshift radio galaxies with Herschel.