All Outputs (408)

Colliding branes and big crunches (2011)
Journal Article
Omotani, J., Saffin, P. M., & Louko, J. (2011). Colliding branes and big crunches. Physical Review D, 84(6), Article 063526. https://doi.org/10.1103/PhysRevD.84.063526

We examine the global structure of colliding domain walls in AdS spacetime and come to the conclusion that singularities forming from such collisions are of the big-crunch type rather than that of a black brane.

Situating the subject: gender and entrepreneurship in international contexts (2011)
Journal Article

Purpose The purpose of this paper is to offer a perspective to further the understanding of gender entrepreneurship. This paper considers the situatedness of the gendered entrepreneur within diverse international contexts marked by different constit... Read More about Situating the subject: gender and entrepreneurship in international contexts.

Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites (2011)
Journal Article
Collier, C., Machon, C., Briggs, G. S., Smits, W. K., & Soultanas, P. (2011). Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites. Nucleic Acids Research, 40(2), https://doi.org/10.1093/nar/gkr785

Bacterial nucleoid associated proteins play a variety of roles in genome maintenance and dynamics. Their involvement in genome packaging, DNA replication and transcription are well documented but it is still unclear whether they play any specific rol... Read More about Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites.

The boundary volume of a lattice polytope (2011)
Journal Article
Hegedüs, G., & Kasprzyk, A. M. (2011). The boundary volume of a lattice polytope. Bulletin of the Australian Mathematical Society, 85(1), https://doi.org/10.1017/S0004972711002577

For a d-dimensional convex lattice polytope P, a formula for the boundary volume vol(δP) is derived in terms of the number of boundary lattice points on the first [d/2] dilations of P. As an application we give a necessary and sufficient condition fo... Read More about The boundary volume of a lattice polytope.

Who applies and who gets admitted to UK graduate entry medicine?: an analysis of UK admission statistics (2011)
Journal Article
Garrud, P. (2011). Who applies and who gets admitted to UK graduate entry medicine?: an analysis of UK admission statistics. BMC Medical Education, 11(Septem), Article 4. https://doi.org/10.1186/1472-6920-11-71

Background Graduate-entry medicine is a recent development in the UK, intended to expand and broaden access to medical training. After eight years, it is time to evaluate its success in recruitment. Objectives This study aimed to compare th... Read More about Who applies and who gets admitted to UK graduate entry medicine?: an analysis of UK admission statistics.

Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers (2011)
Journal Article

Gastric absorption of feruloylquinic acid and di-O-caffeoylquinic acid analogs has never been investigated despite their potential contribution to the proposed beneficial health effects leading to reduced risk of type 2 diabetes. Using a cultured gas... Read More about Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers.

Cell death pathology: Cross-talk with autophagy and its clinical implications (2011)
Journal Article

Autophagy is a self-digesting mechanism that cells adopt to respond to stressful stimuli. Morphologically, cells dying by autophagy show multiple cytoplasmic double-membraned vacuoles, and, if prolonged, autophagy can lead to cell death, “autophagic... Read More about Cell death pathology: Cross-talk with autophagy and its clinical implications.

Electrophysiological measures of conflict detection and resolution in the Stroop task (2011)
Journal Article
Coderre, E. L., Conklin, K., & van Heuven, W. J. (2011). Electrophysiological measures of conflict detection and resolution in the Stroop task. Brain Research, 1413, https://doi.org/10.1016/j.brainres.2011.07.017

Conflict detection and resolution is crucial in a cognitive task like the Stroop task. Previous studies have identified an early negativity component (Ninc) as a prominent marker of Stroop conflict in event-related potentials (ERPs). However, to what... Read More about Electrophysiological measures of conflict detection and resolution in the Stroop task.

Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials (2011)
Journal Article

We assess the evidence for health benefits of three commonly consumed plant food supplements (PFS), green tea, isoflavone and aloe vera, based on published systematic reviews of randomised controlled trials (RCTs). Whilst the potential benefits of gr... Read More about Review of the efficacy of green tea, isoflavones and aloe vera supplements based on randomised controlled trials.

The Effect of Standard and Transepithelial Ultraviolet Collagen Cross-Linking on Human Corneal Nerves: An Ex Vivo Study (2011)
Journal Article

Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation (2011)
Journal Article

Gap junction (GJ) mediates intercellular communication through linked hemichannels from each of two adjacent cells. Using human and mouse models, we show that connexin 43 (Cx43), the main GJ protein in the immune system, was recruited to the immunolo... Read More about Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation.

Knockdown of embryonic myosin heavy chain reveals an essential role in the morphology and function of the developing heart (2011)
Journal Article
Rutland, C. S., Polo-Parada, L., Ehler, E., Alibhai, A., Thorpe, A., Suren, S., …Loughna, S. (2011). Knockdown of embryonic myosin heavy chain reveals an essential role in the morphology and function of the developing heart. Development, 138(18), https://doi.org/10.1242/dev.059063

The expression and function of embryonic myosin heavy chain (eMYH) has not been investigated within the early developing heart. This is despite the knowledge that other structural proteins, such as alpha and beta myosin heavy chains and cardiac alpha... Read More about Knockdown of embryonic myosin heavy chain reveals an essential role in the morphology and function of the developing heart.

Fractionation of lead in soil by isotopic dilution and sequential extraction (2011)
Journal Article

Environmental contextThe chemical reactivity of lead in soil is difficult to assess and depends on both soil conditions and the origins of the lead. This paper tests the combined application of lead isotopic techniques and chemical extraction against... Read More about Fractionation of lead in soil by isotopic dilution and sequential extraction.

The pattern of learned visual improvements in adult amblyopia (2011)
Journal Article
Astle, A. T., Webb, B. S., & McGraw, P. V. (2011). The pattern of learned visual improvements in adult amblyopia. Investigative Ophthalmology & Visual Science, 52(10), https://doi.org/10.1167/iovs.11-7584

Purpose. Although amblyopia is diagnosed in terms of a monocular letter acuity loss, individuals typically present with deficits on a wide range of spatial tasks. Many of these deficits can be collapsed along two basic visual dimensions (visual acuit... Read More about The pattern of learned visual improvements in adult amblyopia.

Measurement and error of hoof horn growth rate in sheep (2011)
Journal Article

Determining the rate of hoof horn growth in sheep is important for understanding the physiology and pathology of the foot and the impact of the environment and the treatment of diseased feet on foot health. It could lead to improved understanding of... Read More about Measurement and error of hoof horn growth rate in sheep.

Organization of the Regenerated Nerves in Human Corneal Grafts (2011)
Journal Article

The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors (2011)
Journal Article

It is now acknowledged that G protein-coupled receptors, the largest class of drug targets, adopt multiple active states that can be preferentially stabilized by orthosteric ligands or allosteric modulators, thus giving rise to the phenomenon of path... Read More about The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors.

Regional variation in angiotensin converting enzyme activity in the human placenta (2011)
Journal Article

Sensitivity of chorionic plate arteries to angiotensin II (AngII) is greatest at the placental periphery. Angiotensin converting enzyme (ACE) is central to the synthesis of AngII and is present in the placental vasculature. We measured vascular ACE a... Read More about Regional variation in angiotensin converting enzyme activity in the human placenta.

The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth (2011)
Journal Article
Chang, C.-Y., Hobley, L., Till, R., Capeness, M., Kanna, M., Burtt, W., …Sockett, R. E. (2011). The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth. Microbiology, 157(11), https://doi.org/10.1099/mic.0.052449-0

Bdellovibrio bacteriovorus grows in one of two ways: either (i) predatorily [in a host-dependent (HD) manner], when it invades the periplasm of another Gram-negative bacterium, exporting into the prey co-ordinated waves of soluble enzymes using the p... Read More about The Bdellovibrio bacteriovorus twin-arginine transport system has roles in predatory and prey-independent growth.

Towards an understanding of neuroscience for science educators (2011)
Journal Article
Oliver, M. (2011). Towards an understanding of neuroscience for science educators. Studies in Science Education, 47(2), https://doi.org/10.1080/03057267.2011.604478

Advances in neuroscience have brought new insights to the development of cognitive functions. These data are of considerable interest to educators concerned with how students learn. This review documents some of the recent findings in neuroscience, w... Read More about Towards an understanding of neuroscience for science educators.