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Preventing childhood obesity during infancy in UK primary care: a mixed-methods study of HCPs' knowledge, beliefs and practice (2011)
Journal Article

Background There is a strong rationale for intervening in early childhood to prevent obesity. Over a quarter of infants gain weight more rapidly than desirable during the first six months of life putting them at greater risk of obesity in childhoo... Read More about Preventing childhood obesity during infancy in UK primary care: a mixed-methods study of HCPs' knowledge, beliefs and practice.

P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the Aurora-B Kinase Inhibitor barasertib-hQPA (2011)
Journal Article

Background Aurora kinases play an essential role in orchestrating chromosome alignment, segregation and cytokinesis during mitotic progression, with both aurora-A and B frequently over-expressed in a variety of human malignancies. Over-expression of... Read More about P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the Aurora-B Kinase Inhibitor barasertib-hQPA.

An investigation of the failure mechanisms in high temperature materials subjected to isothermal and anisothermal fatigue and creep conditions (2011)
Journal Article

Many engineering components are subjected to conditions which have a detrimental effect on the materials from which they are made. Such components are used, for example, within high temperature regions of aeroengines (e.g. turbine discs) and power pl... Read More about An investigation of the failure mechanisms in high temperature materials subjected to isothermal and anisothermal fatigue and creep conditions.

A review of recent developments in climate change science. Part II: The global-scale impacts of climate change (2011)
Journal Article

This article presents a review of recent developments in studies assessing the global-scale impacts of climate change published since the Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report (AR4). Literature covering six main im... Read More about A review of recent developments in climate change science. Part II: The global-scale impacts of climate change.

Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer (2011)
Journal Article

Background and purpose Deregulated redox systems provide cancer cells protection from increased oxidative stress, such as that induced by ionizing radiation. Expression of the thioredoxin system proteins (thioredoxin, thioredoxin reductase and thior... Read More about Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer.

A review of recent developments in climate change science. Part I: Understanding of future change in the large-scale climate system (2011)
Journal Article

This article reviews some of the major lines of recent scientific progress relevant to the choice of global climate policy targets, focusing on changes in understanding since publication of the Intergovernmental Panel on Climate Change Fourth Assessm... Read More about A review of recent developments in climate change science. Part I: Understanding of future change in the large-scale climate system.

Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes (2011)
Journal Article

Affymetrix GeneChip microarrays are a powerful tool to study global gene expression profiles and have been used on many species. However, no sheep-specific Affymetrix GeneChip is currently available and the bovine array is fairly limited in its cover... Read More about Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes.

The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects (2011)
Journal Article

There is good evidence that the medial prefrontal cortex (mPFC) is involved in different aspects of recognition memory. However, the mPFC is a heterogeneous structure, and the contribution of the prelimbic (PL) and infralimbic (IL) cortices to recogn... Read More about The effect of catecholaminergic depletion within the prelimbic and infralimbic medial prefrontal cortex on recognition memory for recency, location, and objects.

Possible roles for folic acid in the regulation of trophoblast invasion and placental development in normal early human pregnancy (2011)
Journal Article

In addition to its role in the prevention of neural tube defects, folic acid has many other physiological functions, including cell proliferation, DNA replication, and antioxidant protection. The aim of this study was to determine the role that folic... Read More about Possible roles for folic acid in the regulation of trophoblast invasion and placental development in normal early human pregnancy.